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  1. Twilio is laying off 17% of workforce (twilio.com)
    452 points by akmittal 375
  2. We work a 4-day week and just raised $4.75m (ryanleecarson.tumblr.com)
    452 points by ryancarson 179
  3. Million requests per second with Python (medium.com)
    452 points by d_theorist 169
  4. Ask HN: How would you turn Twitter around?

    If you were the CEO of Twitter, what would you do in 2017 to make Twitter great again?

    452 points by bsvalley 601
  5. PostgreSQL 14 Internals Book (postgrespro.com)
    452 points by kelvich 34
  6. Chemical clears Alzheimer's protein and restores memory in mice (nature.com)
    452 points by coris47 138
  7. The most cited deep learning papers (github.com)
    452 points by sdomino 47
  8. Where are the robotic bricklayers? (constructionphysics.substack.com)
    452 points by bookofjoe 543
  9. Quickemu: Quickly run optimised Windows, macOS and Linux virtual machines (github.com)
    452 points by overbytecode 133
  10. Rotoscoped Animation of Filmed Parkour (moral.net.au)
    452 points by ropable 49
  11. Let's remove Quaternions from every 3D Engine (marctenbosch.com)
    452 points by Glench 175
  12. Travis CI acquired by Idera (blog.travis-ci.com)
    452 points by involans 131
  13. Johns Hopkins Launches Center for Psychedelic Research (hub.jhu.edu)
    452 points by infodocket 94
  14. You probably don't need a JavaScript framework (slack-files.com)
    452 points by Svenskunganka 347
  15. Photographs of 19th Century Japan (cosmographia.substack.com)
    452 points by merothwell 132
  16. TSA: Fail (gmancasefile.blogspot.in)
    452 points by vamsee 116
  17. How it feels to learn JavaScript in 2016 (medium.com)
    452 points by jjperezaguinaga 189
  18. The Daily Mail Stole My Visualization Twice (flowingdata.com)
    452 points by thehoff 138
  19. Kickstarter switches to Stripe (kickstarter.com)
    452 points by pc 177
  20. hiccupFX.js (hiccupfx.telnet.asia)
    452 points by rvieira 78
  21. How to Be an Expert in a Changing World (paulgraham.com)
    452 points by jayzalowitz 117
  22. GitLab reinstates list of servers that have malware (about.gitlab.com)
    452 points by dwaxe 93
  23. Show HN: BandMatch – “Tinder” but for finding musicians to create bands/collab (bandmatch.app)
    452 points by pg5 222
  24. The myth of NASA's expensive space pens (kottke.org)
    452 points by jwdunne 133
  25. Skillsoft Buys Codecademy for $525M (skillsoft.com)
    452 points by boeingUH60 120