Ask HN: Would you use a cord bank?
We are expecting our first child in August and have seen a lot of adverts for cord blood banking - the idea is that the blood in your baby's umbilical cord contains stem cells that might be useful for curing diseases later in life and so you should bank the blood as a form of insurance. The ads and marketing literature are very compelling, but of course that's what they're designed for! We've done a little basic research, and it looks like not everyone agrees that banking cord blood is desirable (e.g. see http://en.wikipedia.org/wiki/Cord_blood_bank). However, as my wife pointed out, while the organizations in that wikipedia article who
recommend against banking are the kinds of people who should know what's best for mothers and babies, they don't necessarily seem like the best people to judge the potential effectiveness of stem cell therapies.
I'm posting this in the hope that there are some biotech folks reading Hacker News who can cut through the marketing spin and give us a straight answer - would you do this yourself, for your own children?
36 comments
[ 3.8 ms ] story [ 77.6 ms ] threadCongrats by the way! This is a very exciting time. My daughter is an absolute joy and I'm sure your child will be for you too. Good luck!
http://www.cbsnews.com/stories/2009/03/09/politics/100days/d...
Its an old post, but the point is you use your cells for this. I guess I was a misinformed in the reasons for the Obama bill. Nevertheless I don't see why there is no big push to show that you don't need to kill babies to get stem cells!
"What would you recommend for a family member" gets a noticeable change of demeanor/gravity.
Before I tried this approach, I would get "you might want to consider having your tonsils removed. Have a nice day" over and over again for about 8 years.
After I tried this approach it was, "Go see an ENT and have them removed immediately!". From the same doctor who was otherwise afraid of insurance related referral paperwork.
Here's my blog post on it: http://athomedad.justinchen.net/storing-cord-blood
http://www.marrow.org/HELP/Donate_Cord_Blood_Share_Life/How_...
I'm not planning on having kids any time soon, if you couldn't tell. ;-)
I tend to open a few HN topics at once in different tabs, and in the time it was taking me to work through the chafe I was thinking about the arbitrage between downtown real-estate and the ULTIMATE FLEXIBILITY OF ANY CORD AT ANY TIME!!!11OMG
I paid 20 years of storage for both of them also. I believe in the future their stem cells will be beneficial to them in at least one area of their lives, and I hope never to need the cord bloods for health reasons.
But there is one crucial point you should be aware of, make sure they are not sharing personal information or genetic profile with international third parties make sure the service agreement between you and the bank covers this explicitly, banks that I stored my children's bloods had no such clear points in their agreements and i made them add my own no third parties article for me.
We ended up choosing CBR because if the collection doesn't meet a certain threshold you have the option to get a refund or store it anyway. They also guarantee a successful transplant or your money back plus $50000. It cost us just under $2000. We hope it's money thrown away, but if we ever need it it's a small price to pay.
Some banks can also store cord tissue. The way it was explained to me is that the tissue can be used for all the things the blood can be used for, but there's a much better chance it will be a match for the father. Apparently, the chances of the stem cells from the blood being a match for the father are quite low.
That said, I'm having some second thoughts based on some of the things I'm reading here. We have a few more weeks before delivery.
Here's a table of banks and estimated costs: http://parentsguidecordblood.org/content/usa/banklists/summa...
At this point in time you can't know whether or not it will be used later on. But if you don't save it now, if the event happens you won't have it to use. There is also the perspective that if your child never needs it, there might be other kids that it could help years down the road.
You are looking at long term storage of cells, so make sure whoever you go with is legitimate and has a long established history.
For more info, Google: benefits of delayed cord cutting
I think the most honest answer is that even those of us in this field don't yet know if storage of cord blood will prove to offer something that iPS can't. Perhaps there is someone even closer to the intersection of those topics than I on HN who can weigh in.
I'm not really sure why doctors started doing that, but it reminds me of our society's pressure towards having everything natural seem perfect and sort of sterile, like when our grocery stores reject all but the most flawless produce. We wouldn't want our babies to be handed to us with all sorts of icky, biological stuff like still-intact umbilical cords attached.
I'm not sure why the risk of infection would increase with the cord intact versus it being cut (where germs could potentially get in anyway). The baby's and mother's blood don't mix, so even if there were a "wound" on the placenta where it came unattached, that would be on the mother's side.
The thing that became clear during this whole thing is there were going to be MANY times in the coming years when spending "only $3K just in case" was going to be offered and this seemed like a bad precedent to set. The vast majority of children will never benefit from private banking, so go public!
A lot of people want more from medicine than it is ever going to deliver. Just say no to another expensive procedure that has no demonstrable value.
In my case, for my children, I would certainly make sure the blood is saved. The only question is whether to do private cord blood banking or to donate the blood to the public blood bank. I would find out how rare is my child's human leukocyte antigen (HLA) tissue type as part of making the decision. If it's rare then it becomes much, much more important to bank known compatible blood.
One confounding factor: if your child turns out to have a blood disease later in life, it's not clear to me whether there is a risk in using your child's own stem cells. For example we know little about the causes of leukemia, it could be that even the cord blood cells are potentially cancerous. I'd suggest reading up on this and reaching out to researchers in the area on this front, since it's unlikely your OB/GYN would know the most recent results.