Ask HN: Python Programming for Large-Scale Astronomical Data Mining

What are some of the foundational Python programming styles and libraries relative to software used in large-scale astronomical data mining? An example program would be the SETI@home project that utilizes BOINC and the resource pool of distributed computing power of globally accessed personal computers and servers to hunt for radio signals that exhibit specific characteristics outside natural occurrences. To the Python programmers out there, what software packages have you seen of late that best serve as an example that answers this question?