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http://www.pnas.org/content/early/2018/01/25/1718185115

E-cig has been promoted as noncarcinogenic and a safer substitute for tobacco. In fact, recent studies show that E-cig smokers, similar to individuals on nicotine replacement therapy, have 97% less 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), an isoform form of NNK, a tobacco nitrosamine and lung carcinogen, in their body fluid than tobacco smokers.