How long does it take to 'pick up' a language and framework?

I think I could be prepared for pretty much anything within 1 week of intense programming, at least enough for a job.

I have 10 years of experience, unless its something really obscure, I cant imagine it being anything I wouldnt be able to work on.

I would like to make it clear, I would not obviously know the workings like some Java programmer of 10 years.

But would you agree that it takes 1-2 weeks to be ready for anything?