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Figured I'd drop this link here. This is a neat pathway, that scientists in different camps have focused on over the years but haven't necessarily tied to aging biology.

What I find fascinating is that it appears viruses have evolved to exploit our own immune systems against us, and this very exploit underlies heart disease, dementia, and even some cancers.

Is there such a thing as a human zero day?

Thanks and interesting article. I think we're slowly starting to see that more and more processes (not just diseases) are related to different complex interaction between our immune system and pathogens and or even our own body. I think you may be interested in the concept of trained immunity (the innate immune system is smarter than we currently credit it). https://www.ru.nl/english/research/prizes-achievements/spino... Mihai Netea and his department are doing some interesting research :)
I think this may be implying a value judgement that, as always, evolution doesn't make.