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I read the article but don't see a comment on whether the holes will self-repair with stress reduction.
At the end of the article there is a discussion of the impact on patients after getting treatment and learning how to deal with stress, then having brain function return to normal.
I read about brain plasticity. So maybe, before the holes are repaired, brain might be able to rewire itself thus avoid the holes altogether.

Just a guess.

Warning: This site gave me a malware warning in Chrome.
this article is making me stressed.
This site looks identical to New York Times in styling and layout. I wonder if they're owned by the same parent company.