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It looks like people on a Paleo diet have double the amount of TMAO produced in their gut when compared to the general population.

TMAO is a marker that is linked to heart disease and colorectal cancer. It's a marker meaning that it might not be the cause, instead, it could be just a side product.

What is funny is that if you feed meat to people who haven't eaten it in a long time, they don't produce TMAO. This is because their gut no longer has the meat-eating bacteria that produce TMAO.

It's gut bacteria that produce this substance by consuming the meat, and not our body.