Ask HN: How has a near doubling of atmospheric CO2 not affected our respiration?

1 points by ralusek ↗ HN
CO2 is basically poison within the context of our respiration. How has there been no serious biological/performance implications from such a drastic change in atmospheric composition? Obviously as a percentage of atmospheric makeup, CO2 is extremely low, but I would assume that the relative figures are what matters here.

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Atmospheric CO2 concentration is ~0.04%. When you exhale, your breath contains a CO2 concentration of ~3.8%.

Acidosis occurs in humans at atmospheric CO2 concentrations of ~5%.

Looking at statistics of indoor CO2 concentrations, it seems that offices, classrooms and under ventilated spaces often have CO2 concentrations reaching 2%.

I'd posit that there is probably an order of magnitude of leeway in regard to increasing atmospheric CO2 concentration affecting human respiration.

Also of note - we don't have an extensive history of human resting pulse & respiration over generational time (primarily because modern medicine isn't old enough)