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Someone eating durian in a Thai place comes to mind. Always smells like a dumpster in the middle of summer to me, bad enough to start my gag reflex.
I knew at least one comment about the smell of durians would pop up. :-)

Note: I'm a durian lover and would inhale the smell.

Something like that would be very subjective.
thiol chemistry is pretty potent stuff
To me it must be the smell of certain people begging for money, on sleeping in the trains and subways of Berlin. I can't even start to describe what it smells like.
As a chemist, I got to smell a lot of compounds including some terrible ones.

Pure compounds might stink, but it’s usually a very specific smell, so I never found them that bad.

What was the worst was when reactions went bad and created a black tar of decomposition products. Say all your solvent boiled off and the reaction mixture got too hot and burned.

I had done some selenium chemistry at one point and had this happen. Selenium is one row down from sulfur so it had similar odor properties, but more similar to garlic for me. When one of those reactions went bad, it was worse than a sewer.

And the best part was if you got a good whiff, you’d smell it for days since it stuck to your clothes, hair and inside of your nose.

One of the most obnoxious smells was a chemical used to protect nitrogens on a molecule (Cbz). It doesn’t smell that bad, but it reacts with the nitrogen in your nose and it takes 2-3 days to go away. You learn to hate the smell pretty quickly.

Liquid Ass should be in the list. Orginally invented as a novelty prank item, it smells so bad that it is used to train surgeons and combat medics on abdominal wounds and procedures that risk puncturing the intestine.
Don't know about smell but the worst taste is a Nintendo switch cartridge. Well done Nintendo!
Just speculating here, but it sounds like they could add this on purpose to avoid kids from putting cartridges in their mouths and reduce the choking risk.
That is apparently true [1]. Article from 2017.

>Nintendo sent us a statement confirming that the taste is by design:

>> To avoid the possibility of accidental ingestion, keep the game card away from young children. A bittering agent (Denatonium Benzoate) has also been applied to the game card. This bittering agent is non-toxic.

[1] https://www.theverge.com/2017/3/1/14778316/nintendo-switch-c...

Kombucha, which I know is a flavor rather than a smell, but every time I've tried it, I have the sensation of smelling a rotting public waste bin on the side of the road on a hot day--and it's in my mouth.