I kinda understand wanting to have people not rush to testing the drug, though if both are administered by infusion the risk of self-medication is reduced.
I want people to rush to testing all sorts of drugs, this one included.
How quickly should testing of a drug expand? That depends on a balance of risks. The faster you go, the more danger there is of the drug having bad side-effects while you're figuring out how safe and effective it is. The slower you go, the more you delay the possible benefits if the drug ends up working. Right now the potential benefits of such a drug are enormous -- or, put another way, each day of delay is a minor catastrophe. That should tilt the scales a lot.
Sometimes the careful, cautious thing to do is to go fast!
Clarification, I don't want them to self-test, and I agree with you.
I think there's too much hate on that Hydroxycloroquine study and its shortcomings, the risks of testing that are small (though not insignificant and especially not for those with light symptoms) compared to the potential benefits.
Camostat plus E-64d was proposed in a paper in Cell around March 5 as a potential superior prophylaxis under investigation because it blockades the virus from using either ACE2 or TMPRSS2, completely denying SARS-CoV-2 from entering human cells.
It's not a vaccine but it seems possible to prevent infection and possibly halt illness. That is, if it doesn't have any yet unknown, horrible side-effects.
They say that they'll publish the results "in the next days". Anyway it seems to work - maybe that's one of the reasons for the low death count (in relation to infected) in Austria so far.
76 doctors of the state hospital are still in quarantine because of a CoV case in their ranks. Meanwhile, the dermatology building has been converted for the new department, which will help the sick and fight the virus. It now houses the so-called "Covid House". On Friday alone, around 50 patients were examined here on an outpatient basis and 16 were admitted as inpatients, three are in intensive care.
"Data not published, but coming soon"
The Salzburg Primarius Richard Greil, also head of the crisis team, now reports "cautiously good news". There are two new drugs: "One drug can slow down the so-called inflammation storm. The corresponding data have not yet been published. However, they will be published soon. They show that it can achieve a 90 percent reduction in the severity of the disease."
Both are administered by infusion
Greil refers to a substance that is used in the Salzburg department and the Research Centre against Cancer that he heads.
The second drug is said to have a direct effect against the virus. Following hospitals in China, the two preparations are now being used in a test programme at the Salzburg state hospitals. They must be cooled. Already in the next few days they are to be used in Salzburg for severe cases. According to Greil, the test involves infusions that are administered once to the affected patients.
New strategies are also urgently needed, because the number of patients is expected to increase considerably, says Michael Müller, a nurse in Salzburg: "Most of the patients on the ward are in good condition. But I believe that in the future we will get more older patients and patients with multiple illnesses.
That's why it is important to build up more reserves of skilled workers - also for the planned Covid outstation in the exhibition centre, as doctor Patrick Morre from the regional hospitals describes: "We will certainly need more people bit by bit. It would be important and good if even more doctors would get in touch."
Urgently doctors wanted
22 additional physicians have so far come forward, 70 would be needed at Covid House in the state hospital alone. Nursing staff are also urgently sought. They are also facing special challenges, says nurse Teresa Datzmann: "There is great uncertainty about what is still to come.
Pauline Hollaus is also a nurse at Covid House: "You never know how many patients come a day."
Currently, the company is in the process of preparing new employees for their tasks, says nursing service manager Helga Dworschak-Köchel: "There are very specific hygiene guidelines. We also have to qualify employees of the different disciplines". There are 67 beds in the new Covid house, 130 more are planned. The second part of the building is currently being adapted for this purpose.
Advice of the country for infected persons
Those who have few or no symptoms should be cured at home in quarantine. For those who cannot do so, a total of 440 places are now available in separate quarantine quarters throughout the country. Moderately severe cases are to be treated in the military hospital in the Salzburg Exhibition Centre. It will soon have room for up to 800 patients.
Similar facilities are also planned in St. Veit (Pongau) and - if necessary - in Mittersill (Pinzgau). For the seriously ill there is the new Covid Clinic in the Salzburg State Hospital, says Governor Wilfried Haslauer (ÖVP).
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[ 3.4 ms ] story [ 78.3 ms ] threadNot something to get excited about.
Better wait for the article.
How quickly should testing of a drug expand? That depends on a balance of risks. The faster you go, the more danger there is of the drug having bad side-effects while you're figuring out how safe and effective it is. The slower you go, the more you delay the possible benefits if the drug ends up working. Right now the potential benefits of such a drug are enormous -- or, put another way, each day of delay is a minor catastrophe. That should tilt the scales a lot.
Sometimes the careful, cautious thing to do is to go fast!
I think there's too much hate on that Hydroxycloroquine study and its shortcomings, the risks of testing that are small (though not insignificant and especially not for those with light symptoms) compared to the potential benefits.
It's not a vaccine but it seems possible to prevent infection and possibly halt illness. That is, if it doesn't have any yet unknown, horrible side-effects.
Unless I misunderstand the article a lot, this comes from the head of an established hospital, not some Alex Jones equivalent!
Sure, it can still turn out to not work. And "90%" may well not be reproducible. But I'd bet a minor sum on this having a real effect.
76 doctors of the state hospital are still in quarantine because of a CoV case in their ranks. Meanwhile, the dermatology building has been converted for the new department, which will help the sick and fight the virus. It now houses the so-called "Covid House". On Friday alone, around 50 patients were examined here on an outpatient basis and 16 were admitted as inpatients, three are in intensive care.
"Data not published, but coming soon"
The Salzburg Primarius Richard Greil, also head of the crisis team, now reports "cautiously good news". There are two new drugs: "One drug can slow down the so-called inflammation storm. The corresponding data have not yet been published. However, they will be published soon. They show that it can achieve a 90 percent reduction in the severity of the disease."
Both are administered by infusion
Greil refers to a substance that is used in the Salzburg department and the Research Centre against Cancer that he heads.
The second drug is said to have a direct effect against the virus. Following hospitals in China, the two preparations are now being used in a test programme at the Salzburg state hospitals. They must be cooled. Already in the next few days they are to be used in Salzburg for severe cases. According to Greil, the test involves infusions that are administered once to the affected patients.
New strategies are also urgently needed, because the number of patients is expected to increase considerably, says Michael Müller, a nurse in Salzburg: "Most of the patients on the ward are in good condition. But I believe that in the future we will get more older patients and patients with multiple illnesses.
That's why it is important to build up more reserves of skilled workers - also for the planned Covid outstation in the exhibition centre, as doctor Patrick Morre from the regional hospitals describes: "We will certainly need more people bit by bit. It would be important and good if even more doctors would get in touch."
Urgently doctors wanted
22 additional physicians have so far come forward, 70 would be needed at Covid House in the state hospital alone. Nursing staff are also urgently sought. They are also facing special challenges, says nurse Teresa Datzmann: "There is great uncertainty about what is still to come. Pauline Hollaus is also a nurse at Covid House: "You never know how many patients come a day."
Currently, the company is in the process of preparing new employees for their tasks, says nursing service manager Helga Dworschak-Köchel: "There are very specific hygiene guidelines. We also have to qualify employees of the different disciplines". There are 67 beds in the new Covid house, 130 more are planned. The second part of the building is currently being adapted for this purpose.
Advice of the country for infected persons
Those who have few or no symptoms should be cured at home in quarantine. For those who cannot do so, a total of 440 places are now available in separate quarantine quarters throughout the country. Moderately severe cases are to be treated in the military hospital in the Salzburg Exhibition Centre. It will soon have room for up to 800 patients.
Similar facilities are also planned in St. Veit (Pongau) and - if necessary - in Mittersill (Pinzgau). For the seriously ill there is the new Covid Clinic in the Salzburg State Hospital, says Governor Wilfried Haslauer (ÖVP).
https://translate.google.com/translate?hl=en&sl=auto&tl=en&u...
Apparently one drug is an intravenous chemo drug administered only one time.
https://www.evaluate.com/vantage/articles/news/corporate-str...