Ask HN: Are There “Antibiograms for Antihistamines”?“?

1 points by BrandoElFollito ↗ HN
I have a "highly annoying" case of fever hay (allergy to pollen). I use the wording "highly annoying" because I am in the middle of the scale between "a sneeze here and there" and "debilitating". It makes me physically suffer, though - especially during the night.

I consulted several allergists and had skin tests done on several occasions. They all point to allergy to some herbs and trees. The doctors told me I cannot go though desensitization and prescribed several kind of antihistamines across the years.

The problem is that I can hardly quantify whether they work. I usually have in a week 4 or 5 "bad days", and the "badness" is not equal across the day. I could not directly link a pill intake to improvement (or not). I also have the impression that effect fade out after some time of taking a given pill (this is just an impression - due to the above I cannot run any quantitative analysis).

My question: are there equivalents of antibiograms for such treatments?

With an antibiogram you take a sample of your bacterial infection, run several antibiotics and get within 48 hours a list of molecules that may work, and other that will not (because of resistance).

I was hoping there could be an equivalent for antihistamine molecules - showing which are more likely to work. Is this a thing?

Note 1: I am not looking for medical advice, rather for enlightenment on the existence or not of such an approach (and probably learning several things in the process)

Note 2: I am in France, if this matters.

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