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TL;DR: same as reputation on Stack Exchange/Overflow, but a whole lot more complicated for no reason.
The first difficult part of a Stack Overflow clone is to get an initial community of experts. Joel and Jeff had both a well known blogs where they can got people to form the initial community. (HN was created from the readers of the pg blog^H^H^H^H essays.)

The second problem is moderation, that is not an easy task.

My guess is that they can keep the homeopathy folks away, but I'm worry that it will be difficult to filter other stuff like the EmDrive.

And using a crytocoin instead of worthless internet points will solve none of these problems.

Seems more like a convenient way to bury your rivals in downvotes. As if scientists aren't petty enough already?

> 1.8M papers are published each year and most of them are never read

I can confirm from my time writing them that papers are never read.

> 50% of experiments are unable to be reproduced

Please. Nobody ever tries to reproduce experiments.