I'm about to quit my job,take some time off, then maybe move to SF. Any Advice?

Flesh out some ideas to work on before you quit. That way you can tap your early enthusiasm and freedom to create the product as soon as you quit.

When looking for ideas, consider what you'd enjoy using or a tool you wish existed. Have a specific idea of something to learn with each project.

If you are looking to learn Python, Learn Python the Hard Way is excellent: http://learnpythonthehardway.org/index

Depending on how lucky you are, you may only have an opportunity to do this once, maybe twice. +1 to the crowd urging you to wait until you have something you really feel passionate about.

Also, I'm not sure where you reside, but physically uprooting one's entire life is usually a pretty intensive process. Doing that WHILE trying to go out on your own for the first time financially might find you lacking the focus necessary to settle down and get back to work once you do find your passion.

Not sure by moving to San Francisco will relax your brain but if you are to take break than you should be going away from city life for sometime. Than, sit down and think what makes you happy or you want to do further in life. I took 2 months vacation back home India (Punjab) and I must say by brain is as fresh as clean water (hypothetically speaking).

I highly recommend you figure out what you want to do before quitting. Is there a specific company or industry that you're dying to work in? If so, work your ass off to get an interview. If you have passion for starting your own project, do it on the side while you continue to collect a paycheck.

The worst thing you can do is quit and rush into another job that you aren't passionate about (fyi, SF is expensive).

I may do the exact same thing! I've already started: my exit interview is this Thursday.

Statistically, the chances of PG accepting me into this latest YC class are slim to none, so I'll be spending quite a bit of time loading up on leisure and knowledge before making the final decision to bootstrap my startup: training in BJJ/MMA, surfing, and filling in some holes in my CS knowledge. I never received a formal functional programming education, so I'm powering through "The Structure and Interpretation of Computer Programs" on my nook, using Clojure instead of Scheme. I would like to learn more about message queues and NoSQL, maybe some Python like yourself, and clean up some projects I've recently open-sourced. And ruby-serialport, which I maintain, could use another release, perhaps a little website too. Heck, I could use a nicer website...

I have some travel plans as well. Staying with friends in the east coast, and visiting family in South America. Depending on what happens, I may travel more. As a Third Culture Kid, I miss the foreign and new very much. Coincidently, I'm exploring the wild idea of traveling and collaborating with other developers on OSS, a la Paul Erdos, except without the academic papers, or the amphetamines.

My only clearcut advice is not to forget about health insurance. The last thing we need is a broken arm to wipe out our savings.

I wish you the best of luck!