The concerns raised in this article do not speak to the efficacy of candidate vaccines using Ad5 vectors. Rather, they discuss the potential impact Antibody-dependent enhancement might have on at risk groups, and, as a consequence, for the design of clinical trials using those vectors.
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[ 2.7 ms ] story [ 18.6 ms ] threadhttps://www.sciencemag.org/news/2020/10/could-certain-covid-...
The concerns raised in this article do not speak to the efficacy of candidate vaccines using Ad5 vectors. Rather, they discuss the potential impact Antibody-dependent enhancement might have on at risk groups, and, as a consequence, for the design of clinical trials using those vectors.