Villi are tiny “fingers” of tissue that line your intestines, increasing it’s surface area and allow absorption of nutrients and water. It makes the lining of the intestines resemble wet velvet.
Yes, but he is more pointing out that fructose is processed in the liver only (as far as we currently know (glut5)), as such it constitutes an extra stress on the liver.
Fatty liver disease is more prevalent nowadays, and it has largely been decoupled from alcohol (ab)use and more related to fructose , hence it's been called non-alcoholic fatty liver disease.
Has someone read the paper? I wonder if the effect disappears over time. This is, if the villi go back to having the length they had if they stop feeding the mice fructose.
Yeah overfeeding mouse with a single isolated nutrient tells you exactly and only that overfeeding a mouse with that single nutrient is bad.
Giving people actual fruit and telling them to only eat fruit and as much as they want, and 99% of people will lose weight. Not that fruit only diet is good. Just giving an example on how most of this studies are not applicable to humans in real worlds.
You're probably right, but this study has profound implications for consumption of fruit juice, especially highly processed ones like orange juice, soda with high fructose corn syrup and table sugar (50% fructose).
Maybe, but I thought it has been relatively known for a decent while now that fruit juices weren't great for you due to the rate you ingest sugar from it. Maybe we'll learn they are more bad, but it's not like we didn't already know you should limit your sugary drinks.
Big maybe. And still, it is a fake condition with another animal, in an overfeeding condition.
Very large chunk of problems in humans related to nutrition go away if you are not overeating calories.
And I guess nobody would argue that if you would imprison a human being in a horrendous conditions (like mice) and overfeed them extracted HCFS syrup, that they would be a paragon of health.
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Fatty liver disease is more prevalent nowadays, and it has largely been decoupled from alcohol (ab)use and more related to fructose , hence it's been called non-alcoholic fatty liver disease.
Giving people actual fruit and telling them to only eat fruit and as much as they want, and 99% of people will lose weight. Not that fruit only diet is good. Just giving an example on how most of this studies are not applicable to humans in real worlds.
IANAS, but I would expect this mechanism to be present in humans too.
Very large chunk of problems in humans related to nutrition go away if you are not overeating calories.
And I guess nobody would argue that if you would imprison a human being in a horrendous conditions (like mice) and overfeed them extracted HCFS syrup, that they would be a paragon of health.
Why are we paying all these scientists to extend the lives and study the well-being of MICE!
Stupid mice, all they ever do is steal the dog food in winter.
Come-on science! Get with the program.