Regulatory capture kills people, but unfortunately the legislative equivalent means there's not much will to fix it. In this case though not only was there regulatory capture, but J&J and their talc supplier conspired to deceive the FDA. I have little hope the lawsuits will extract more from them than their added profits.
Scandals such as this one are fueling anti-vax movements. I remember learning about physician who found that a drug was causing a massive increase in heart attacks, informed manufacturer, and was ignored. They went on a smear campaign and he was worried he would have issues finding employment as large hospital networks have connections with pharmaceutical companies.
I had an issue with a flouroquinolone antibiotic, many warnings were added by the FDA, but the issue is still underreported and 1 out of 100 doctors would NOT even consider saying those drugs cause issues. Even when it is backed by research. It appears many individuals who suffer from CFS/Fibro/Chronic Pain/Tendonitis/Nerve pain developed it after a treatment. A major problem is that currently there is no test to show flouroquinolones caused the damage and patients may feel normal then get a tendon rupture 8 months later. Look up FQAD if you are curious.
I even spoke to a writer of a book about FQs, his wife was suffering from psychosis after levaquin. This happened in 1986. Many flouroquinolone drugs were taken off the market and replaced by new ones. New research suspects some individuals may have genes causing issues removing those drugs from the body and allowing toxic amounts to accumulate. There is some research looking at possible mitochondrial adducts and dysfunction.
I think Mayo clinic is also doing some studies to figure out what is causing these side effects which can last for years and then disappear completely.
On the other hand, a fluoroquinolone like Cipro might be the only way to treat an MDR bacteria such as P. aeruginosa.
All the black box warnings in the world don't matter if Cipro is the only available drug. Use it or (probably) die. We really need a lot more research into new antibiotics.
I'm all for CIPRO being used in such situations. I would take my chances and use it myself even though I had an awful reaction. I do have a problem with it being used for "suspected" UTI or as a first line medication. Also, the bigger problem is the lack of care after adverse reaction occurs.
Wait, it’s shocking news that an industry council, made up of companies who have a vested interest in data that says their products are safe, shaped a report that does just that?
I’m thinking the FDA is playing fuck-fuck games here. Any time I’ve talked to them they dismiss reports like this right away and look for independent research.
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[ 74.9 ms ] story [ 976 ms ] threadI had an issue with a flouroquinolone antibiotic, many warnings were added by the FDA, but the issue is still underreported and 1 out of 100 doctors would NOT even consider saying those drugs cause issues. Even when it is backed by research. It appears many individuals who suffer from CFS/Fibro/Chronic Pain/Tendonitis/Nerve pain developed it after a treatment. A major problem is that currently there is no test to show flouroquinolones caused the damage and patients may feel normal then get a tendon rupture 8 months later. Look up FQAD if you are curious.
I even spoke to a writer of a book about FQs, his wife was suffering from psychosis after levaquin. This happened in 1986. Many flouroquinolone drugs were taken off the market and replaced by new ones. New research suspects some individuals may have genes causing issues removing those drugs from the body and allowing toxic amounts to accumulate. There is some research looking at possible mitochondrial adducts and dysfunction.
I think Mayo clinic is also doing some studies to figure out what is causing these side effects which can last for years and then disappear completely.
All the black box warnings in the world don't matter if Cipro is the only available drug. Use it or (probably) die. We really need a lot more research into new antibiotics.
I’m thinking the FDA is playing fuck-fuck games here. Any time I’ve talked to them they dismiss reports like this right away and look for independent research.
Pass the buck I guess?