- of the three compounds currently in clinical trials, they’re all relatively similar to known drug compounds, but unnumbered by patents (and hopefully more effective)
- the grand challenge in drug design involves a different objective function than most are currently solving — the real challenge is to identify which protein to target, but most drug discovery assumes a known target and optimizes drug compounds for that target
Protein targets are being slowly elucidated by the exposure of the mechanisms of various biochemical pathways. As we get a more complete picture, the emergent effects should start to become more clear
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[ 2.2 ms ] story [ 15.4 ms ] thread- of the three compounds currently in clinical trials, they’re all relatively similar to known drug compounds, but unnumbered by patents (and hopefully more effective)
- the grand challenge in drug design involves a different objective function than most are currently solving — the real challenge is to identify which protein to target, but most drug discovery assumes a known target and optimizes drug compounds for that target