Setup Python and Django on Mac OS X Lion (hackercodex.com)

After all, not everybody can afford a linux box for their dev :p

Pythonbrew is another good option for dealing with Python and multiple versions of Python.

https://github.com/utahta/pythonbrew

Great step-by-step instructions and set of "best practices" for getting Python, Django and more installed on OS X version 10.7.x (Lion).