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Case study, by nurses, n=2, both middle aged women

However large effect size, using relatively safe otc meds

Very vulnerable to placebo effects, random chance, or comorbid with other issues

Wow, that's disappointing. It probably warrants further investigation, but I don't see how something with only 2 datapoints can be meaningfully published.
It can be meaningfully published as "someone should look into this". That's not nothing.
It can be meaningfully published as a case study, that’s what those are. One or a very small number of cases and what happened. It happens in medicine all the time.
Don't know if it would help, but Curcumin (tumeric extract with a pepper extract to potentiate it) is a near magic anti-inflammatory.

It's totally over the counter and without side effects afaik.

I have dozens of stories about it, just one is guy I worked with was taking Voltaren 2-3 times a day for his shoulder, hadn't played golf for two years. I gave him some and he played golf the next day.

He then went for holidays to UK where his sister and her husband are both doctors and they were taking it prophylactically against early onset Alzheimer's.

It has to have the pepper extract with it to be effective, if you have a sprain or similar it acts in 1-3 hours.

Could be helpful for long covid, chances of harm very low.