This article is partly accurate and partly pseudoscience woo. VO2 Max is inversely correlated with all-cause mortality risk. However, there are no reliable biomarkers for aging.
Relying on telomere length as a measurement of ageing is pseudoscience. We don't have any reliable evidence that this has a causative effect on mortality risk.
I am not familiar with Dr. Attia's claims about obesity. Could you clarify which specific claims you think are pseudoscience?
This article is about telomere length and their relation to the maximum rate of oxygen consumption measured during exercise of increasing intensity.
Yet not all cells divide, for example some neurons and skeletal muscle cells do not divide. These cells will die after some decades and the functionality is permanently lost (and we die).
A roughly similar feat happens for cardiomyocytes (heart cells): They do not divide but transform through endoreduplication or die, this cause one of the main cause of death: Heart failure.
Another thing is that for cells that divide (those for which telomere length matters) there is a replenishing mechanism with progenitor cells (as long as their supply last).
So IMO opinion telomere length is a part but not the whole story about ageing.
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[ 2.7 ms ] story [ 31.7 ms ] threadhttps://peterattiamd.com/ama35/
What part of the article do you believe is pseudoscience?
I am not familiar with Dr. Attia's claims about obesity. Could you clarify which specific claims you think are pseudoscience?
Yet not all cells divide, for example some neurons and skeletal muscle cells do not divide. These cells will die after some decades and the functionality is permanently lost (and we die).
A roughly similar feat happens for cardiomyocytes (heart cells): They do not divide but transform through endoreduplication or die, this cause one of the main cause of death: Heart failure.
Another thing is that for cells that divide (those for which telomere length matters) there is a replenishing mechanism with progenitor cells (as long as their supply last).
So IMO opinion telomere length is a part but not the whole story about ageing.