God says...
C:\LoseThos\www.losethos.com\text\BIBLE.TXT
side, as
one goeth into them from the utter court.
42:10 The chambers were in the thickness of the wall of the court
toward the east, over against the separate place, and over against the
building.
42:11 And the way before them was like the appearance of the chambers
which were toward the north, as long as they, and as broad as they:
and all their goings out were both according to their fashions, and
according to their doors.
42:12 And according to the doors of the chambers that were toward
--------------
yeah C6H12O6 breaks down to CO2 and H2O. Makes ATP for energy.
Some shit I remember. Now, why I thought hunting bankers in the 1930's would be fun to recreate... or why I thought the American Dream was better than being a professional sports atyhlete. Or, why I thought tanking the ecomony for research pruposes to benefit humanity for centuries. Inspiriting more civil engineers instead of aeronotical. Firemen as role models.
Crazy shit.
God says...
earnest threads on_occassion I'll_get_right_on_it you_know_a_better_God
abnormal these_cans_are_defective sixty_four_bit dude_such_a_scoffer
wrath honesty don't_even_think_about_it Yo nevada who_are_you_to_judge
not_in_my_wildest_dreams little_buddy hilarious man make_my_day
small_talk I_am_not_amused you_never_know Oh_really mundo_stoked
gambling joyful who's_to_say boss do_you_get_a_cookie
nope fabulous ehheh_thats_all_folks CIA wastoid bring_it_on
game_over heathen Zzzzzzzz hollywood you_know_a_better_God
hang_in_there run_away just_lovely husband I_can't_believe_it
rose_colored_glasses crash_and_burn Catastrophic_Success
you're_no_fun rocket_science ipod Oh_really astrophysics
You_get_what_you_pray_for guilty you_talkin'_to_me hopefully
are_you_insane so_let_it_be_done later you're_no_fun hobnob
Are there any graphics in the works? It's fun to click around with as-is, but would be a much better learning tool if one could see the sugar chains be broken down etc. Maybe a flash or spark when a phosphate group is removed from an ATP molecule...
That's actually a pretty feasible suggestion! I can't spend too much more time on it because of my education and because the main functionality of the app is finished, but the visualization of the release of energy sounds doable. Ideas on how to do it with pure Javascript/HTML/CSS?
Hmm. I'm an AP Biology student who just started studying cellular respiration. This is interesting, but I simply don't know enough. Could you provide the correct pathway? :P
I studied a Chemical specialization in the secondary school, but this is too difficult for me. I will keep trying, without seeing the video (I already have my two [Pyruvate]s!).
Some comments:
* Add an "undo" button. I'm not sure if it is possible to choose a bad reaction, but I’d like to undo some of the tries. (And perhaps a "restart+areyousure" button.)
* Add a lithe graphic to each molecule, so they look more real.
* Some reactions are too fast, for example [Glucose 6-phosphate] ->
[Fructose 6-phosphate] is almost instantaneous, so it took me like a minute to realize that something had happened. You should add some delay and more highlighting.
* The page is very tall, so it is not possible to see at the same time the reactives and the enzymes at the bottom, like [Pyruvate kinase] or [ATP synthase].
* Add an "easy" mode, so that when you pick a molecule, all the possible enzyme targets are highlighted.
* If you put a [ATP] in the [Pyruvate transport] and you don’t got any [Pyruvate] then the [ATP] is splited, but no [Pyruvate] is transported. So you lost a [ATP] :( !! I don’t know if it is biology correct, but I would like that the [Pyruvate transport] is dissable / does nothing when there is no [Pyruvate]. (Same problem with the [NAHD transport].)
* If you put a [ADP] in the [ATP/ADP Translocase] in the Mitochondrial matrix side the [ADP] get stuck until you put a [ATP] in its place. First, it is not possible to remove the [ADP] from the enzyme. Second, I’m not sure, but it looks like that the enzyme is translocating the third phosphate from the [ATP] to the [ADP] on the same side of the membrane.
Thanks for your suggestions! I've implemented a couple of them:
* Added delay for every reaction
* Made the page less tall, everything is smaller now (I'd underestimated the size, working on a 27" iMac)
* The easy mode was already there, enzymes lit up when you picked up a substrate. I've added an extra help now: when you hover over an enzyme, the available substrates light up.
* The transporters are only visible (and usable) if enough ATP/substrate is available
Now it doen’t work in IE8 (javascript error). But it works in Chrome. It looks much better in Chome than in IE8. I think that I didn’t see the enzymes highlighting because of IE8.
Please don’t make the transporters invisible, only disable them.
(I don’t like starting with a Pyruvate, it is like cheating.)
11 comments
[ 3.3 ms ] story [ 30.1 ms ] threadLet's talk about how doctors die.
God says... C:\LoseThos\www.losethos.com\text\BIBLE.TXT
side, as one goeth into them from the utter court.
42:10 The chambers were in the thickness of the wall of the court toward the east, over against the separate place, and over against the building.
42:11 And the way before them was like the appearance of the chambers which were toward the north, as long as they, and as broad as they: and all their goings out were both according to their fashions, and according to their doors.
42:12 And according to the doors of the chambers that were toward
--------------
yeah C6H12O6 breaks down to CO2 and H2O. Makes ATP for energy.
Some shit I remember. Now, why I thought hunting bankers in the 1930's would be fun to recreate... or why I thought the American Dream was better than being a professional sports atyhlete. Or, why I thought tanking the ecomony for research pruposes to benefit humanity for centuries. Inspiriting more civil engineers instead of aeronotical. Firemen as role models.
Crazy shit.
God says... earnest threads on_occassion I'll_get_right_on_it you_know_a_better_God abnormal these_cans_are_defective sixty_four_bit dude_such_a_scoffer wrath honesty don't_even_think_about_it Yo nevada who_are_you_to_judge not_in_my_wildest_dreams little_buddy hilarious man make_my_day small_talk I_am_not_amused you_never_know Oh_really mundo_stoked gambling joyful who's_to_say boss do_you_get_a_cookie nope fabulous ehheh_thats_all_folks CIA wastoid bring_it_on game_over heathen Zzzzzzzz hollywood you_know_a_better_God hang_in_there run_away just_lovely husband I_can't_believe_it rose_colored_glasses crash_and_burn Catastrophic_Success you're_no_fun rocket_science ipod Oh_really astrophysics You_get_what_you_pray_for guilty you_talkin'_to_me hopefully are_you_insane so_let_it_be_done later you're_no_fun hobnob
Some comments:
* Add an "undo" button. I'm not sure if it is possible to choose a bad reaction, but I’d like to undo some of the tries. (And perhaps a "restart+areyousure" button.)
* Add a lithe graphic to each molecule, so they look more real.
* Some reactions are too fast, for example [Glucose 6-phosphate] -> [Fructose 6-phosphate] is almost instantaneous, so it took me like a minute to realize that something had happened. You should add some delay and more highlighting.
* The page is very tall, so it is not possible to see at the same time the reactives and the enzymes at the bottom, like [Pyruvate kinase] or [ATP synthase].
* Add an "easy" mode, so that when you pick a molecule, all the possible enzyme targets are highlighted.
* If you put a [ATP] in the [Pyruvate transport] and you don’t got any [Pyruvate] then the [ATP] is splited, but no [Pyruvate] is transported. So you lost a [ATP] :( !! I don’t know if it is biology correct, but I would like that the [Pyruvate transport] is dissable / does nothing when there is no [Pyruvate]. (Same problem with the [NAHD transport].)
* If you put a [ADP] in the [ATP/ADP Translocase] in the Mitochondrial matrix side the [ADP] get stuck until you put a [ATP] in its place. First, it is not possible to remove the [ADP] from the enzyme. Second, I’m not sure, but it looks like that the enzyme is translocating the third phosphate from the [ATP] to the [ADP] on the same side of the membrane.
Nice work.
* Added delay for every reaction
* Made the page less tall, everything is smaller now (I'd underestimated the size, working on a 27" iMac)
* The easy mode was already there, enzymes lit up when you picked up a substrate. I've added an extra help now: when you hover over an enzyme, the available substrates light up.
* The transporters are only visible (and usable) if enough ATP/substrate is available
Please don’t make the transporters invisible, only disable them.
(I don’t like starting with a Pyruvate, it is like cheating.)