2012 predictions for entrepreneurs?

Hello everyone.

Looking at the 2012-2015 time-frame, what in your opinion would be the biggest opportunities for entrepreneurs?

Popular opinion blogs express that Gamification will see a rise, so will Personal Marketing with the help of Mobile platforms. Social VS Traditional forms of business will evolve to a more combined form of working. Lead Generation for sales/marketing is another unexplored area for automated solutions.

What is your take on these or some other untapped avenues where starters can look for traction and impact?

PS: I'm currently bootstrapping. It would be wonderful to have some perspective from such a mature community.