There is always a good time for some shameless auto-promotion, so I'll mention Triggr, a package which allows one to convert R process into a fast, event-based XML-, JSON- or even more freestyle RPC server: https://github.com/mbq/Triggr
R has exceptional libraries for doing statistical analysis. This kind of setup could be a great platform for building a statistical software suite as a service. Sort of like SAS or STATA or SPSS in the cloud.
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