For the usual case of DEFLATE-based formats (PNG, ZIP) and JPEG, ECT [1] is the best available tool; to my best knowledge it dominates the entire Pareto frontier in this area, beating Zopfli and ADVPNG/OUT for most cases. If this software is still being maintained, it would be a good choice to switch to ECT now.
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[ 2.8 ms ] story [ 34.6 ms ] thread[1] https://github.com/fhanau/Efficient-Compression-Tool
That's no longer lossless.
I guess I’ll have to include it in my own benchmarking suite I’m developing.