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highly dependent on chemical properties of the drug and physical properties of the delivery.

could be overtly toxic, cause deleterious effects, reduced efficacy, inhibited or rephased uptake.

dont risk it unless you have professional expertise

Common things like ibuprofen, cough medicine, allergy meds- seem fine after 5 years at least. Probably degraded if you leave them in a steel shed in the sun.
Liquid Tylenol is not effective after expiration from my experience. It did not reduce pain or fever. New bottle worked as expected.
Did not read the article, but my lay perspective is that the chemicals will degrade over time into different molecules due to particle radiation from neutrinos and the like. Just given enough time, the original product no longer has any potent chemical effect.
Right. But I don't think we're concerned about whether an archaeologist from 50,000 years from now can take them. A 3-10 year window is too short for such radiation to have an effect.