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this provides a good prompt for appreciation of cellular events at intermolecular scale.

generally, the physics, and physical chemistry of colloids, and colloidal systems are basic to such pursuit.

Alan Kay speaks about this in his 1997 OOPSLA keynote at about this point https://www.youtube.com/watch?v=aYT2se94eU0&t=1960s
sophomore level biology was the first official mention of how misrepresentative most depictions are. decried as cartoons, and void biased suggestions of a particular aspect of function.

it was really expressed best as statistical examination of contacts and degrees of freedom.