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0cf8612b2e1e 

  The researchers found that male athletes with an exercise volume of >3,000 MET-minutes/week showed higher mean coronary artery calcification (CAC) scores than nonathlete males (mean difference = 31.62). No difference in CAC was found for male athletes with 1,500 to 3,000 MET-minutes/week or female athletes with an exercise volume of 1,500 MET-minutes/week or greater.
Not sure what a MET minute is, but 3000 minutes per week is 7 hours per day, seven days a week. So, this sounds like a problem for approximately zero percent of the population.
BryanBigs
Tennis is a 5MET activity, jogging/running can be 10+
adamgordonbell
Chatgpt says it would be on the order of 8 hours of running a week. So similar to many marathon training routines.
PaulHoule
My cardiologist told me I was doing too much cardio and I shouldn’t do more than an hour a day.
drewbitt
For the vast majority of the population, more exercise is better. But there is an upper limit to the cardiovascular benefits of exercise.
Nappes
Pace of 9 minute per mile is ~12 Mets/M

So maybe doing 30miles a week at that pace = 30Miles * 9 Min * 12 Mets/Min = 3000 Met/Mins/Wk

0cf8612b2e1e
Ok, so say a four miles/day routine. High, but actually attainable for mortals.