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Sounds great. I'll buy one. Where's the kickstarter?
A company called AVACore has the rights, and they charge a hand and a leg for it (~$2000, and apparently only sell to select groups). I looked into making one myself based on the published papers. It doesn't seem too hard but probably just a bit outside of my proficiencies.

Edit: I just discovered a DIY link to it, so looks like others had the same idea. Now that the trail has been blazed maybe I'll look into it again. http://www.instructables.com/id/CoreControl-DIY/

I'm thinking of all the exercise we participate in that has us wrapping our hands around something and holding on, which essentially limits our palms ability to release the heat. If these handles were cooled, would we see the same effect?
My understanding is that they key components are the vacuum and the extreme cold. The vacuum allows a lot more heat to be transferred than there would be in anything held onto.
You're making the assumption that a vacuum can't be wrapped in your hand. Though I'm thinking a simple perforated tube which sucks the air out would act as a vacuum.