Ask HN: Wordpress nested multisites - or any alternative?

After checking the requirements for one of our partner sites we would like to consolidate, Wordpress almost fits them, especially with the Network/Multisite feature. There is only one catch: we would like to use nested multisites, like the following different sites:

domain.com/ [#0: admin site] domain.com/en/ [#1: English info pages] domain.com/fr/ [#2: French info pages] domain.com/en/blog1 [#3: English blog with long articles] domain.com/en/blog2 [#4: English blog with short news snippets]

The examples above are of course simplified, but I hope you get it: different parts might have different management, different content and update cycle, sometimes (eg. through language change) different theme. e.g. domain.com/en/about-us shall be served by #1, /en/blog1/some-post shall be served by #3.

Do you have any experience with such setups? What is the catch? Is there any alternative?

Thanks!