“The conception before was that, when it came to nucleosomes, genes were either turned on or off, but we’re finding it’s more like a volume dial,”

this is not a new paradigm. this was apparent in the late 80s.

modulation of DNA / nucleosomal binding affinity, is a known epigenetic mechanism for the last 35 years.

DNA expressivity is not digital, its result of many affinity based interactions over time contributing to a summary result in the form of conformational change or rate of reaction.

So you're telling me that cells use an attention system for DNA?

After reading that amazing title, I skimmed the whole article several times looking for the part about DNA existing outside the cells.