A long time ago, while I am not a scientist nor a MD, I implemented the kind of PSSM* peptide vaccine in PHP and I put the code on Github, then a few years later I removed it. Indeed for the reasons explained in this excellent article it is considerably obsolete now.
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[ 0.45 ms ] story [ 8.4 ms ] threadThe implementation is still online:
https://padiracinnovation.org/en/peptide_PoC/
* position-specific scoring matrix
PSSM itself is fascinating, it has some similarity to Transformers. In another timeline and with much evolution it could have lead to LLMs.