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Pretty cool.

I've never been a fan of these full-JS layouts though, they chug so hard if the browser isn't Chrome!

Personally if I was gonna go for this kind-of JS framework thing I'd use EXT JS... http://extjs.com/products/extjs/

Sometimes I feel there are more frameworks than any useful implementations of them
didn't get a chance to look at it too hard but it doesn't seem to support back button, which is a pain in the ass
Wouldn't it be nice to use this framework for business web apps! Quick and responsive interface, easy to construct layouts around complicated business logic...

Not, actually.

A surprisingly large part of my enterprise prospects/clients have javascript switched off completely, and a a large part of them still use IE6!

It is tempting to ignore a dinosaur client who is still on IE6, but when the dinosaur happens to be a top manager at a large bank -- that makes you think.

As a result I am minimizing/eliminating JavaScript and sticking to simple html forms. Hell, I even have replaced all PNGs with GIFs after a IE6 user complained he couldn't see the charts.

It is a pity, of course, but business users' environment is a bit different from consumers' one.

I'm using javascriptMVC ( www.javascriptmvc.com ). Please check this framework out to build the community of users! Thanks :)