Ask HN: Save two different desktop layouts on OSX for different environments?

I'm basically in two different modes when I work on my macbook. In one mode, I have a few apps running in desktop 1, another in desktop 2, a few in desktop 3 etc. Then when I switch from work to school mode, I want to run an entirely different layout at the click of a button instead of closing applications, retiling them, making new workspaces, and re-organizing everything.

Anyone know how to accomplish this? Maybe two different user accounts and just log in and out of both? But then it won't 100% preserve the state of everything, like when you close the lid and re-login..