Ask HN: What charities do you donate to?

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kiva.org -- small loans (usually around $1,000 total, crowd-sourced in $25 increments) made to people for new business ventures, farm improvements, etc. Definitely worth a look!
Also a big fan of Kiva. Been involved with it for years.
I'd love to donate to an organization who's charter was ending the drug war, but I'm not sure I know of one specifically like that. I suppose NORML might be an obvious choice, but I don't feel like picking a specific drug for promotion is where my heart is. I don't really know much about organizations in this field. Anyone?
Amnesty and Naturskyddsföreningen
Almost all of my donations goes to local non-profits that my wife or I are on the board of or where I intimately know the organization's board, staff, and mission. I also usually support money raising efforts of friends for small amounts (like a walkathon).

The vast majority of the money is going to organizations that provide services to low-income people.

If you are looking for non-profit ideas that help the kind of giving I do, check out Razoo. Another thing those organizations could use is a way to lower operational costs, potentially by pooling with others.

90% to whatever GiveWell -- http://givewell.org -- currently thinks is best (GiveDirectly, Against Malaria Foundation), 10% to charities I have a soft spot for that I suspect are less efficient (e.g. EFF, Wikimedia, public radio).
There are too many good causes, so I decided to follow my mothers approach: Pick two/three and give them all the donations that I can make. From that point on I ignore every other charity in the world.

The only charity I support that I suspect anybody will have heard of would be the RNLI (Royal National Lifeboat Institution; the folks that go out and rescue people at sea http://en.wikipedia.org/wiki/Royal_National_Lifeboat_Institu... )

Usually I donate once a year to my chosen three charities, bot sometimes there will be a small bonus at random times.