Modeling Human Drug Trials — Without the Human (wired.com)

And so Eddy hit on the idea of a soup-to-nuts model that would capture everything known by modern medicine, from the evolution of disease in different people — as shaped by factors like race, genetic risk, and number of hours spent doing yoga — to specific physiological details, such as the amount of heart muscle that dies in the hours after a heart attack and the degree to which medications like aspirin can limit that damage.