another important point to notice is affinity. While 8 uM looks impressive, it is not that hard to develop such potency since compounds are likely to aim ATP binding pocket. It is big, deep and offers many hydrogen bond…
another important point to notice is affinity. While 8 uM looks impressive, it is not that hard to develop such potency since compounds are likely to aim ATP binding pocket. It is big, deep and offers many hydrogen bond…