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  1. 1 points 0
  2. Creators of Tailwind laid off 75% of their engineering team (github.com)
    1457 points 244
  3. SimpleFold: Folding proteins is simpler than you think (github.com)

    https://arxiv.org/abs/2509.18480

    471 points 37
  4. Why HNSW is not the answer and disk-based alternatives might be more practical (blog.pgvecto.rs)
    138 points 64
  5. The New Drones the SFPD Will Be Using (and Is Already Using) (sfist.com)
    1 points 0
  6. Over 1M websites are at risk of sensitive information leakage (salt.security)
    6 points 0
  7. Cheap $63 macOS Sonoma Hackintosh with Dedicated GPU [video] (youtube.com)
    3 points 0
  8. Deepgram Aura, Conversational Text-to-Speech for Voice AI Agents (deepgram.com)
    1 points 0
  9. Cellulose film could help cool cars and homes without electricity (techspot.com)
    1 points 0
  10. A self-generating story that gets longer the more stars it gets (github.com)
    42 points 8
  11. AI model finds potential drug molecules 1000x faster (news.mit.edu)
    2 points 0
  12. The Qubit Game – Build a quantum computer, one qubit at a time (quantumai.google)
    1 points 0
  13. Wordle Oracle – Predict tomorrow's word (codepen.io)
    1 points 0
  14. The brief history of San Francisco's most dangerous (and absurd) secret society (sfgate.com)
    3 points 0
  15. High-Quality Free Image and Video API (pexels.com)
    1 points 0
  16. Crispr Is Dead (josiahzayner.com)
    2 points 0
  17. Contact-free Haptics (ultraleap.com)
    2 points 0
  18. Show HN: Spry – Build Ecommerce with Google Sheets

    Hi HN, Jay (memset) and Len here. We've built Spry (https://spry.store), a tool that allows you to create an ecommerce site just using Google Sheets and Stripe. We think it's easier to use than the alternatives and…

    10 points 8
  19. GitHub’s Plan to Freeze Your Code for Thousands of Years (thenewstack.io)
    3 points 0
  20. Quantum Supremacy Could Happen This Year (scientificamerican.com)
    1 points 0
  21. Autoped – Electric Scooter from 1915 (en.wikipedia.org)
    1 points 0
  22. Show HN: Browsertron – Run all your Selenium tests in parallel (browsertron.com)
    50 points 11
  23. Better than a hologram: BYU study produces 3D images that float in 'thin air' (news.byu.edu)
    2 points 1
  24. How We Built a Tool to Export React Prototypes from Sketch (medium.com)
    1 points 0
  25. State Governments Are Already Gaming the Republican Tax Overhaul (bloomberg.com)
    2 points 0