> There are researchers that claim this makes it an even more virile cancer causing agent. This is exceedingly vague, but also seems to fall into "extraordinary claims" territory. We know the proteins SV40 expresses…
Not the GP poster, but some answers: > Does SV40 cause cancer? Yes, in a range of animal models at least. SV40 can 'immortalise' cells, turning off regulatory functions which prevent uncontrolled division, which is an…
Setting aside my bias about whether my large glass of wine last night was one drink or two, I find the claims in this post odd. None of the issues noted seem inherently problematic, and indeed several are as I would…
Most radiobiological effects for acute exposures are actually quadratic in dose - this applies to things like mutations, chromosome aberrations, and lethal events. The quadratic term relates (loosely) to interactions…
The article is a bit unclear, but we have both a very wide range of X-ray vs charged particle studies, and increasingly of conventional vs FLASH studies with a range of modalities (e.g. the seminal FLASH paper was FLASH…
That phrasing isn't perfectly clear, as there's two things at play. If you're delivering a large dose D all at once, FLASH spares normal tissue compared to conventional rate irradiations, with maintained anti-tumour…
It's probably worth noting that there's a lot of discussion about challenges reproducing the workflow of this paper, and that as-described it seems to suffer from data leakage, so much so that you can replace sections…
This is generally good advice, but isn't it inappropriate in this specific instance? The lady's claim was (allegedly) that she has a perfect ability to distinguish between the tea-milk orders, so in that case even a…
> There are researchers that claim this makes it an even more virile cancer causing agent. This is exceedingly vague, but also seems to fall into "extraordinary claims" territory. We know the proteins SV40 expresses…
Not the GP poster, but some answers: > Does SV40 cause cancer? Yes, in a range of animal models at least. SV40 can 'immortalise' cells, turning off regulatory functions which prevent uncontrolled division, which is an…
Setting aside my bias about whether my large glass of wine last night was one drink or two, I find the claims in this post odd. None of the issues noted seem inherently problematic, and indeed several are as I would…
Most radiobiological effects for acute exposures are actually quadratic in dose - this applies to things like mutations, chromosome aberrations, and lethal events. The quadratic term relates (loosely) to interactions…
The article is a bit unclear, but we have both a very wide range of X-ray vs charged particle studies, and increasingly of conventional vs FLASH studies with a range of modalities (e.g. the seminal FLASH paper was FLASH…
That phrasing isn't perfectly clear, as there's two things at play. If you're delivering a large dose D all at once, FLASH spares normal tissue compared to conventional rate irradiations, with maintained anti-tumour…
It's probably worth noting that there's a lot of discussion about challenges reproducing the workflow of this paper, and that as-described it seems to suffer from data leakage, so much so that you can replace sections…
This is generally good advice, but isn't it inappropriate in this specific instance? The lady's claim was (allegedly) that she has a perfect ability to distinguish between the tea-milk orders, so in that case even a…