totalperspectiv

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  1. ish is a CLI tool for searching records using alignment methods. It’s record-type aware and supports lines, FASTA, and FASTQ. I was really pleased with the dev experience using Mojo. It’s still pre-1.0 and missing a few…

  2. Preprint can be found here: https://www.biorxiv.org/content/10.1101/2025.06.04.657890v1 Code can be found here: https://github.com/BioRadOpenSource/ish

  3. Learning about FNV Hash (ducktape.blot.im)
  4. I remember a while back there was a paper showing that depending on the length of your username, you might have different program performance, and the directory that you ran from also had an effect. What was that paper?

  5. If you could try to sell some of the old languages today (Ada, Fortran, Pascal, etc), what would be their elevator pitch? Are there one or two tools that could bring them back into relevance?

  6. I would classify Microsoft Access, Excel, etc in those. Software that allows a power user to adapt to changing requirements and constraints over time.

  7. At $work we have an opportunity to potentially open source a lot of our code, but it will take a huge paradigm shift within the company. It would make a lot of sense from a technical perspective to open up the repos and…

  8. LuaVela – A LuaJit Fork (eliasdaler.github.io)
  9. Is it even possible? How do you as a developer, not become a lifetime maintaimer?

  10. I have a project that I've worked on in my free time that is in the same field as what I do at work. I'm not sure how or if I can open source it without potential issues. Has anyone else delt with this before? There is…

  11. What happened?

  12. Does anyone have any recent experience benchmarks different workloads with or without hyperthreading? Are there general characteristics that would indicate better runtime without hyperthreading? All the resources I've…

  13. Twitter and HN have become my go to's for content. But HN has high number of off topic posts for my interests (which has the upside of exposure and cross pollination). Twitter is good, but has a lot of rambling,…