One interesting aspect of Vitamin D that is not regularly discussed is the photo-isomerization of Vitamin D into inactive isomers in the skin. I think of it similarly to Beta-Carotene, in that consuming the "natural…
When I did my master's thesis on Vitamin D supplementation the conclusion was that vitamin D testing is wildly inaccurate, and we needed to have studies based on a target level - ideally one based around sub-saharan…
You may have a point about processing, but I think by talking about "most people" you have invalidated any future points you may be trying to make. For example: "single natural ingredient" not every cow is only fed with…
I've stopped using photos entirely due to import bugs. So much wasted time, now I just use image capture to import and organize directly. Still get errors from time to time. Apple needs to hire more quality control,…
The hypothesis was: is it beneficial to supplement vitamin D to reach the maximum levels achieved through sun exposure year-round? Conclusion: these types of studies did not exist at the time, but the risks of doing…
Thank you for replying!
Curious. Could you please share your physical activity level around the time of supplementation? One of the most interesting studies I found in my research of vitamin D was a study in an elder care center where the…
Other than the value you are aiming for (I personally aim for the upper edge of the normal range), I agree with the immense variability in dosage, and also would like to mention imprecision in vitamin D bloodwork tests…
Adding on this point, in my research I found blood serum testing to be wildly imprecise. The conclusion of my study was that we should do more studies where we take regular blood level samples and adjust dosage to…
Did a masters on Vit D. Multiple overdoses of over 1 million IU have been recovered from without obvious long-term damage present in near term follow up. Out of vitamin D’s many potentially clinically positive effects…
testing lying down as we speak. Much more comfortable. The killer market for this device is business airline travel.
15 minutes of full-body UV exposure from the sun is estimated to provide the equivalent of 20-30,000 IU Vitamin D3. There is a definite need for studies that better determine the effective dose for D3. My research led…
Makes sense that we have been cooking for a long time. Our intestines look as though they have evolved around an environment of cooked food, and that takes many many thousands of years
Distributed ledgers are not a scam, and our true best hope for anti-corruption. I would like every elected official to have all their income and spending listed on a public ledger. True accountability of representatives…
Chiming in to thank you. The access to quality information on the web, specifically Ebooks, is what gives me hope for the future.
I tried the exact setup of this 1000+ hours person, having been excited by the concept of a monitor-less office for years. My current setup is multiple 4k monitors in pixel-doubled resolution. It is relatively easy on…
Welcome! I highly recommend the study - even though the numbers are low, the data is very interesting.
I didn't mention K2 because I didn't study it. I make no claim to expertise, only familiarity. Personally, I eat dark green leafy vegetables every day - one serving of kale contains 443% daily value of vitamin K and I…
It depends - ancient ancestors had a lot of different lifestyles. For example, Soranus of Ephesus reported deformations in the bones of children as early as the 100 CE. However, this is I think what you are trying to…
My thesis argued that we should not be testing supplementation levels, instead we should be testing the effects of maintaining people at various serum levels of vitamin D year-round.
In acute hypervitaminosis D, there can be organ calcification that has to be treated. These cases are rarely reported - one case occurred when the patient ingested crystalline vitamin D - dosing themselves in the range…
There are many cases of kidney disorders causing issues in vitamin D metabolism - the majority of literature examples I read involved genetic kidney disorders which would not be be caused by increased calcium…
I noted the levels needed to maximize intestinal calcium absorption because this is the best studied aspect of Vitamin D. Rickets was the main reason Vitamin D was discovered and supplemented. Vitamin D level blood…
I personally aim for 10,000 IU D3 daily from either sun or supplement. In normal times, living in New York, I would supplement 10,000 IU D3 from November through March, and then I would make sure to be outside 1 hour a…
Yes, this was overly brief and a tilde is not enough to qualify this statement, and I should have said noon equatorial sun. My point here was meant to be about how this is essentially the daily maximum dose from UV…
One interesting aspect of Vitamin D that is not regularly discussed is the photo-isomerization of Vitamin D into inactive isomers in the skin. I think of it similarly to Beta-Carotene, in that consuming the "natural…
When I did my master's thesis on Vitamin D supplementation the conclusion was that vitamin D testing is wildly inaccurate, and we needed to have studies based on a target level - ideally one based around sub-saharan…
You may have a point about processing, but I think by talking about "most people" you have invalidated any future points you may be trying to make. For example: "single natural ingredient" not every cow is only fed with…
I've stopped using photos entirely due to import bugs. So much wasted time, now I just use image capture to import and organize directly. Still get errors from time to time. Apple needs to hire more quality control,…
The hypothesis was: is it beneficial to supplement vitamin D to reach the maximum levels achieved through sun exposure year-round? Conclusion: these types of studies did not exist at the time, but the risks of doing…
Thank you for replying!
Curious. Could you please share your physical activity level around the time of supplementation? One of the most interesting studies I found in my research of vitamin D was a study in an elder care center where the…
Other than the value you are aiming for (I personally aim for the upper edge of the normal range), I agree with the immense variability in dosage, and also would like to mention imprecision in vitamin D bloodwork tests…
Adding on this point, in my research I found blood serum testing to be wildly imprecise. The conclusion of my study was that we should do more studies where we take regular blood level samples and adjust dosage to…
Did a masters on Vit D. Multiple overdoses of over 1 million IU have been recovered from without obvious long-term damage present in near term follow up. Out of vitamin D’s many potentially clinically positive effects…
testing lying down as we speak. Much more comfortable. The killer market for this device is business airline travel.
15 minutes of full-body UV exposure from the sun is estimated to provide the equivalent of 20-30,000 IU Vitamin D3. There is a definite need for studies that better determine the effective dose for D3. My research led…
Makes sense that we have been cooking for a long time. Our intestines look as though they have evolved around an environment of cooked food, and that takes many many thousands of years
Distributed ledgers are not a scam, and our true best hope for anti-corruption. I would like every elected official to have all their income and spending listed on a public ledger. True accountability of representatives…
Chiming in to thank you. The access to quality information on the web, specifically Ebooks, is what gives me hope for the future.
I tried the exact setup of this 1000+ hours person, having been excited by the concept of a monitor-less office for years. My current setup is multiple 4k monitors in pixel-doubled resolution. It is relatively easy on…
Welcome! I highly recommend the study - even though the numbers are low, the data is very interesting.
I didn't mention K2 because I didn't study it. I make no claim to expertise, only familiarity. Personally, I eat dark green leafy vegetables every day - one serving of kale contains 443% daily value of vitamin K and I…
It depends - ancient ancestors had a lot of different lifestyles. For example, Soranus of Ephesus reported deformations in the bones of children as early as the 100 CE. However, this is I think what you are trying to…
My thesis argued that we should not be testing supplementation levels, instead we should be testing the effects of maintaining people at various serum levels of vitamin D year-round.
In acute hypervitaminosis D, there can be organ calcification that has to be treated. These cases are rarely reported - one case occurred when the patient ingested crystalline vitamin D - dosing themselves in the range…
There are many cases of kidney disorders causing issues in vitamin D metabolism - the majority of literature examples I read involved genetic kidney disorders which would not be be caused by increased calcium…
I noted the levels needed to maximize intestinal calcium absorption because this is the best studied aspect of Vitamin D. Rickets was the main reason Vitamin D was discovered and supplemented. Vitamin D level blood…
I personally aim for 10,000 IU D3 daily from either sun or supplement. In normal times, living in New York, I would supplement 10,000 IU D3 from November through March, and then I would make sure to be outside 1 hour a…
Yes, this was overly brief and a tilde is not enough to qualify this statement, and I should have said noon equatorial sun. My point here was meant to be about how this is essentially the daily maximum dose from UV…