Ask HN: I'm writing a book about white-collar drug use, including tech sector

542 points by Eilene ↗ HN
Hi HN. I’m a journalist who wrote ‘The Lawyer, The Addict’, a story that ran in the New York Times in July. The story was about my ex-husband, Peter, who was a high-flying powerful partner in Wilson Sonsini (the prestigious, Palo Alto-based law firm) and who died in July 2015, a drug addict. Almost everyone in his life missed the signs. The story wound up with enormous traction and was the 55th most read story in the entire paper in 2017. It also generated several threads of commentary on HN, including https://news.ycombinator.com/item?id=14776864, https://news.ycombinator.com/item?id=14931209 and https://news.ycombinator.com/item?id=14777919.

I’m now writing a book based on that story for Random House. Although it is about what happened to Peter, the broader story is about the problem of substance use (and often abuse) in white-collar professions, where the users are well-off, well-educated, working long hours, often with all the outward trappings of success.

What can you tell me about drug use as a professional or in your profession?

I know there is drug use in law, finance, medicine and technology, and am hoping that some of you will be open to discussing with me what you see and what you've experienced in your profession and professional environment. I’d like to use some of your comments in the book and will not know or need to know your names, so I hope you’ll feel comfortable being as candid as possible. I’m not here to make judgements, all I’m looking for is the truth about what’s going on.

I'm interested in whatever you can tell me about drugs you are using or observe being used in your field: which drugs, what effects you see, any stories you have, any details you can share. Thanks.

641 comments

[ 3.4 ms ] story [ 341 ms ] thread
Perhaps an email to send you stories anonymously would be good.
please send to zimmermaneilene@gmail.com.
Perhaps an email to send stuff anonymously would be good.
of course. please send to zimmermaneilene@gmail.com.
This looks like it might be your personal email. Consider protecting yourself by making a temporary email for the purposes of your research such as booktitle@gmail.com.
Journalists tend to want people to be able to contact them. The spam etc. is just the cost of doing business.
Or better, consider protecting those offering their experiences as well by using an encrypted email provider like protonmail, or offering a GPG key.
I don't know what those are, I'm sorry. I'm not in the industry (software engineering/tech) so am not familiar with those (though I know they exist). Is it something I can do in the next hour?
I'd suggest going through https://www.privacytools.io/#email. These providers won't give your data to NSA or third party companies(or at least this is more likely, than with another provider like google). Given you are asking for some sensitive data, I'd suggest you use one of these, at least for this specific project if you can't make the move completely.
I appreciate the caution, thank you. That email is what gets funneled from my website, so it's fine. It's not my personal personal email. It's for the book.
Now you and Google will know!

Consider using a mail provider that is not in the business of selling personal information.

Adderall and Cocaine.

I remember a CEO of one of my early startups would give me 5mg addies to help me get more done. I appreciated it because it was great to get the added boost to focus.

I eventually worked my way up to taking 30mg of XR daily (legally, doctor prescribed) and it was the most productive I have ever been in my life. I worked 24x7. I was working a normal consulting job while also working on a startup/app in my spare time. I did ui/ux/frontend/backend/api development and sent cash overseas for an iOS developer that I managed. None of this would have been possible without stimulants.

It's only way to do some of the things that the really successful engineers are doing. You forgo eating, exercise, etc... and spend 110% of your time on working and chasing the high of getting shit done.

It's not sustainable though. I eventually went cold turkey. I do NOT recommend that as it will completely ruin your life for 6 months to a year. I was not productive, I gained tons of weight, my self-confidence went to shit. My life really went into a downward spiral.

Now I am 100% drug-free and am not at the same level I was back then, but I am very productive and focused. I would not go back to where I was, even for the productivity gains. I eat clean (low-carb, ketogenic), weightlift in my basement, row 5k/10k every few days for cardio. My only vice is really coffee and the low-carb cocktails on weekends. Best of all, I do not wake up in the morning needing a tiny pill full of amphetamine salts.

Any chance you can explain why? Not enough hours in the day kind of thing? Is the only route to success in software engineering to work 24/7?
I think a human being is really only capable of like 6 hours of solid mental work throughout the day. And even that is tough, with all the distractions of modern life. When you take something like Adderall, that doubles to, say 12 hours and enables you to get hyper-focused on the task at hand. Sure, you can still get hyper-focused on the wrong thing, but if you can reign that in you're golden.

Not only that, the amount of things you accomplish in that time span is far greater. So it really does turn you into a 10x engineer. If you're already very strong, experienced, pragmatic, etc.. then the stimulants will truly make you feel invincible.

So if you see a software engineer at a big company who is making 200k a year while simultaneously putting out dozens of open source projects a year, maintaining them, speaking at conferences, managing complex hobbies, etc... chances are that is due to a stimulant drug. I know very few people who are capable of that naturally.

Out of curiosity, did the stuff you learned during that time also increase 10x? Did it all stick with you, or did it just temporarily increase your ability to hold it all in your head?
Yes, absolutely. It's still here, thankfully :)
It's great for long-term memory, but short-term memory loss is a side effect of amphetamines. You can read a textbook and retain all of it, but you may not remember where you put it when you finished.
Very insightful, I think, about the exec at a big company. A therapist who treats tech people in Sil Val said she has been told there is coke being done openly at some exec committee/board meetings, etc. and pressure to do it. Like Wall Street in the 1980s. Do you think there's any validity to this?
I'm not so sure about that (never seen it myself)... but cocaine is a LOT more prevalent than people realize.

There is a funny meme I saw recently that rings true:

    Two biggest shocks of adult life. 

    1. everyone does cocaine

    2. cheese is fucking expensive
Man, I really wouldn't. My understanding is that of the people who present to the emergency department with chest pain, something like a third of them have been using cocaine. It causes Real Problems.

https://www.drugabuse.gov/publications/drugfacts/drug-relate...

thanks for the link. I need to find updated stats on that. I wonder if the number of those in the ER because of cocaine has risen....
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This is a little disingenuous, without further elucidation. As far as the statistic you have quoted is concerned, it tells us nothing about how dangerous cocaine is. We need to know how many out of the total population of cocaine users experience chest pain, how many of them go to an ER, and then how many of those (who in total make up 1/3 of ER presentations with chest pain) are further diagnosed with some actual serious problem...

if we don't know what the outcome of these ER visits are, then it could well be that for some tiny percentage of cocaine users there is a side effect that causes the perception of chest pain, which disappears with no ill effects after a few hours. or, maybe, this represents almost all cocaine users - 90% of them experience severe enough chest pain to warrant an ER visit, all of whom are pronounced dead withing minutes of arrival.

annoyingly, the website you linked to which details this singular datum, does nothing to clarify as to what the truth of the matter is. it certainly doesn't appear to be "advancing addiction science" in any useful way...

That could also mean a third of the population uses cocaine.
While I'd give you the point, my personal experience is that its only prevalent in certain circles, and in those circles its EXTREMELY prevalent.
I don't think this is actually true. I've certainly been in places where there have been people on cocaine (and sneaking off the bathroom to "top up" mid-party), but in my experience that's rare, and even rarer for it to be an in-your-face, obvious thing. There are certain social/professional groups where it _is_ the norm, but more so in the sense of being a "vocal minority".
As someone who has been on stimulants since they were thirteen, you still only have 6 hours of productive time. You just also have 6 hours of flailing about like a headless chicken. Sure it'll help you with mundane and routine tasks, but not with stuff that requires a ton of brain power.

Edit: What I see a lot of is people who think they are super productive while churning out lines and lines of garbage.

If it feels more like flailing now than super productivity, have you stopped taking stimulants (or do you have to because of an attention issue)?
I have to. For me stimulants help me put my six hours of productivity to work. I have pretty severe ADHD.
This is very true. I didn’t realize I had ADHD until after a year of college, but basically the first few days of taking stims are basically borderline hypo manic - you havw (seemingly) limitless enrgy, enthusiasm, confidence, drive. Work is intrinsically fun (although it’s actually extrinsic since it’s drug induced).

Then tolerance rears its head and it becomes exactly like you said. For me it takes till I get close to t_max (peak blood concentration) that my day really starts, which is from 1-3 hrs after dosing (closer to 3 for the drugs I take)

(comment deleted)
That's the perception, and you're likely to find that perception in this thread, but I don't believe it.

Work smart or go home.

(comment deleted)
This is an addict's (unreliable) perception, not reality. In reality, software engineers are so valuable and highly sought after that you can have basically any lifestyle you want and still be successful.
What made you decide to go cold turkey? (which sounds almost not-doable it's so tough). Did you hit some kind of wall? And would you mind commenting on what you think happens to engineers who don't use some kind of stimulant?
I went cold turkey because I did not like the fact that I needed the drug to go about my day. I also started to get into crossfit/fitness and the really high dose stimulants made intense exercise feel like it was taxing my body way more than it should have.

I wanted to achieve everything naturally. I knew going off the drug would slow me down, but I was willing to trade general health and well-being for a drop in productivity.

Do you ever feel like everyone around you is doing some substance to make them work faster or better, and that you'll somehow fall behind or be at a professional disadvantage if yo don't?
I felt that sense while I was down in the dumps after going cold turkey ... but now that I have more of a grasp on my life (married, dog, money in savings, living a healthy lifestyle, etc...) I no longer feel that way.

I don't live in Silicon Valley any longer though... so that might be part of the reason I don't feel the pressure.

Right now I might call myself a big fish in a little pond (not really, I am more humble than that) but compared to SF where you are a small fish in a big pond ... there is a lot more pressure to stand-out and be excellent.

Good point. And I'm interested in knowing how being in SV, as opposed to outside that particular fish bowl, affects drug use
My anecdote: In undergraduate engineering, a lot of the people around me were on ritalin. I never felt disadvantaged because I felt it didn't give anyone a clear advantage in the hardest subjects like mathematics or nonlinear control. From what I saw, it didn't seem to improve intelligence that much; rather it helped the distractable people to not get distracted from studying for example.
Suddenly ceasing stimulants does not involve nearly as acute or prolonged a withdrawal as opiates. There's no risk of seizures like there is with benzos. Your dopamine receptors will reset their tolerance much quicker than the 6 months I see cited throughout this thread. I have stopped stimulants many times with no more than a 1 week (maybe 10 day max) period of physical dependence symptoms.

When people experienced prolonged withdrawal symptoms from ceasing stimulants, I think it is usually due to being forced to confront life conditions that were being avoided.

I'm wondering if it's life conditions in many cases that is part of the reason for using in the first place? Yes, needing to work long hours is very real, but maybe the drugs also help to avoid life conditions that we don't want to deal with...
I see "helps me work" used pretty often as a rationalization for drug use that's actually a coping mechanism.
> I think it is usually due to being forced to confront life conditions that were being avoided.

This certainly may be part of it.

However, there are long-term changes in the brain that occur with chronic stimulant use/abuse. I'm looking for the correct number, but I believe it takes about 24 months for the brain to revert to its normal state after stimulant cessation.

Source? (not nitpicking, genuinely curious)
I'm pretty busy so I can only do a cursory search. I cannot find the source I originally read this on, however I will try to find it when I am at home.

Here's what I could find via a preliminary Google search on my phone:

From drugabuse.gov [0]:

> In the aforementioned study, abstinence from methamphetamine resulted in less excess microglial activation over time, and abusers who had remained methamphetamine-free for 2 years exhibited microglial activation levels similar to the study’s control subjects. Another neuroimaging study showed neuronal recovery in some brain regions following prolonged abstinence (14 but not 6 months). This recovery was associated with improved performance on motor and verbal memory tests. But function in other brain regions did not recover even after 14 months of abstinence, indicating that some methamphetamine induced changes are very long lasting.

Here's a graphic they included [1].

This is another source [2]:

> Stopping drug use doesn’t immediately return the brain to normal. Some drugs have toxic effects that can kill neurons—and most of these cells will not be replaced. And while changes to connections between neurons in the brain may not be permanent, some last for months. Some research suggests the changes may even last for years.

I cannot find the studies these articles cite, but I'll try to find them later.

This is related, but is not specific to stimulant or methamphetamine use:

Delta-FosB, an enzyme that is critical to achieve an addiction state in the brain, has a half-life of ~208hr [3]. Multiply that by the standard 7 half-lives to estimate significant elimination, and that alone yields a maximum of 60 days until it is cleared. This enzyme is key in drug and behavioural addictions.

This paper [4] speculates about changes in the brain that last longer than the time it takes to eliminate elevated Delta-FosB levels in the brain.

[0] https://www.drugabuse.gov/publications/research-reports/meth...

[1] https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/met...

[2] http://learn.genetics.utah.edu/content/addiction/brainchange...

[3] http://www.jneurosci.org/content/jneuro/17/13/4933.full.pdf

[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC58680/#__sec5ti...

"changes in the brain" is too vague to be useful.

Post Acute Withdrawal Syndrome (PAWS) is supposedly a thing that can last months, but it's just an observation of a collection of symptoms - no analysis of a specific mechanism causing it that I have seen.

> "changes in the brain" is too vague to be useful.

I would hope that someone trying to do something useful concerning addiction and the brain wouldn't go by a comment on Hacker News that was posted via a cell phone.

Anyway, please see my comment here: https://news.ycombinator.com/item?id=16477351

Seeing a manager go this path, and seeing his productivity plummet, I'm pretty sure the productivity boost is merely perceived.

There was a story on HN with people trying to microdose on LSD, and the alleged benefits - long story short, when they asked peers about their performance, they noticed they're more distracted and not more productive, while those doing the microdosing thought they're on a super productive trip.

We notice this manager is in a constant state of "brain fog" to a point where his speech changed (like he's drunk), while I'm pretty sure he thinks he's a 10x machine and wouldn't be able to pull all of his workload off without drugs.

You get more sick days, you need more time to recharge, while thinking you're on your absolute productivity peak. And when you crash, you're basically unemployable / unproductive for 6 months to 1 year.

Not worth it IMHO.

Is this manager still going this route? And do you think any of the microdosing (or other drug use) goes beyond the 10x productivity stuff? Could it be some of the tedium of programming work? Does it relieve any of that? I'm trying to determine too if all of the drug use in tech is really aimed at enhancing performance/productivity or if it's also used to stave off depression, anxiety or just that feeling so many of us have and have had that we're not doing anything particularly meaningful in our professional work. Peter was very depressed, so I understand why he did opioids, for sure. And he had an immense workload, so the amphetamines also make sense.
> I'm trying to determine too if all of the drug use in tech is really aimed at enhancing performance/productivity or if it's also used to stave off depression, anxiety or just that feeling so many of us have and have had that we're not doing anything particularly meaningful in our professional work.

This is a fascinating possibility, and apparently there's at least one researcher working on exactly that. [1][2]

On a much lesser level, I know this is a common reason for the divide between focus tips ("listen to white noise, silence, or wordless music to avoid distraction") and people's self-report techniques ("listening to intense EDM helps me code"). The goal isn't to avoid distraction, it's to break through tedium and help code longer without losing focus. I'd hardly be surprised if more intense things like LSD microdosing had similar effects.

Anecdotally, I know at least one very skilled programmer who insisted she couldn't work without marijuana. She didn't think THC did anything to raise her core abilities, but rather said that it stopped her from getting impatient or bored and let her work more methodically for longer.

[1] https://www.scientificamerican.com/article/the-problem-with-...

[2] http://www.tandfonline.com/doi/abs/10.1080/21507740.2014.990...

The emotional blocks to productivity are a very real phenomenon. I've only ever done this once, but I pushed through a really annoying emberjs refactor through Ballmer Peaking overnight.
I completely agree. When I'm unhappy with my productivity, part of my self-assessment involves taking a careful look at my emotional state and seeing if there's anything there that isn't compatible with the calm/attentive/enthusiastic/alert combination where I do my best work. And if I turn something up, I either switch tasks, take some time off, or try to resolve the impediment one way or another.
Thanks for the links.
Ha! I was just noticing this recently, smoking a joint early in the day makes it easier for me to focus and way more productive.
Microdosing LSD and taking adderall are going to have completely different effects. That’s a pretty apples to oranges comparison. I can’t imagine how any dose of LSD would ever increase productivity, but adderalls benefits as a stimulant are pretty well documented - you will be able to stay up and focused longer, although as you noted you may end up paying for it in other ways.
As someone who has both microdosed LSD and taken smal amts (<5 mg) of d-methamphetamine, LSD can certainly increase productivity. It’s a similar energy boost as any of the ‘phetamines, but without the classic linearity.

Note: to have an effective microdose you have to take a small amount. <=5ug. I tried 25ug and it was basically a super light trip (distinctive lsd body high and everything).

Anyway, for 98% of people microdosing won’t help productivity in the long run.

Edit: just to preempt the obvious questions, I’m talking about oral methamphetamine, I’ve never smoked it. Orally, d-meth is just objectively better than amphetamine (okay, that’s subjective, but the peripheral stimulation of, say, l-amphetamine is a huge negative)

I think this kind of goes with the idea that if you want to do something then you will do it. Drugs are not as simple as "If I take this pill it will make me do my homework I don't want to do.", but it makes you focus on whatever is really on your mind. I hear stories from people all the time that they will do whatever drug to help them get something done, but instead end up cleaning there house and such. If you really want to be working on what you are then the drugs will help you not to care about anything but that.
Stimulants are not free energy, that’s for sure - my impression is you get more done for 2 days, nothing done for 1 and less done for 2 days, making it a net loss of productivity. So they’re ultimately only useful in short spurts where haste is needed.
as somebody diagnosed with adhd at older age and that is taking ritalin (legally) i would say it helps a lot. but im taking less then prescribed because i dont want to be dependent on it. i always wondered it the effect is stronger for somebody without adhd.
> i always wondered it the effect is stronger for somebody without adhd

i've wondered this myself. i often hear people say stuff like "people with real adhd can't get high from stims", but i suspect that some of this is just that people want to distance their legitimate use from those tweakers over there.

if there's any truth to it, i'd bet it comes down to the way the drug is used. when you take an extended release formulation (or instant release every n hours) regularly, you tend to have relatively stable blood concentrations of the drug (ie, you don't get "high"). recreational users, and also probably people who self medicate, will end up with peakier blood levels, which results in the perception of being "high". the concentration level over time can be an extremely important factor in how the drug ultimately affects you.

> "people with real adhd can't get high from stims", but i suspect that some of this is just that people want to distance their legitimate use from those tweakers over there.

I don't know if "High" is the right word. I've accidentally taken too much, and it makes me super impatient, which makes me kind of an asshole. I've also taken WAY too much on accident, and it just made me paranoid and think my heart was beating out of my chest.

I will say, being on a normal amount is kind of the best kind of high. Living with ADHD is like drowning, like you have these short moments of coming up for air and being productive, but quickly become distracted for everything else.

Being on the right amount, is like someone finally shut all the extra TVs off in the back of my brain. Like there's no challenge in determining the priority of what needs to be done. I feel human, not anxious, not depressed by my inability to remember where I put my keys 30 seconds ago. and thus, more productive.

Now I don't claim that my experience with ADHD is like another's, but this is my experience.

Thanks for the explanation, really good imagery. I hope you took some acidic vitamin C when you overdosed to kill the metabolism of amps.
I was prescribed too high of a dose of Adderall for ADHD once, and I had what could be described as a manic episode, with some mild hallucinogenic effects. I was awake for 36 hours straight without any fatigue, and my resting heart-rate was elevated by almost 20bpm.

It was terrifying enough that I don't think I'll ever abuse the stuff, but I can definitely believe that some people would like the feeling.

On the other hand, correctly dosed Focalin significantly reduces my symptoms (as in I go from being unable to complete a simple 5 sentence e-mail to being able to be mostly on-task). Avoiding all simple-carbs before noon significantly improves the efficacy of it as well for me (a traditional sugar/starch american breakfast would make me hypoglycemic around the middle of the day).

I think it’s the same for any drug that has the potential for abuse but is medicinal, such as opiates or cannabis.

When you have to take it day in, day out just to feel more normal, the dosage is either too low for pleasurable effects or tolerance negates them, and the side effects start to wear on you. Since it’s something you’re legitimately doing just to feel normal, but you inadvertently suffer from some of the drawbacks of drug addiction, ultimately you'd rather not be doing it.

they're more like an energy loan, and you better believe there's interest.
I came to the same conclusion after taking modafinil daily for 5 months. I quit because I was getting completely drained by 7pm. I had to hit the bed as soon as I got home, and then slept for 10-12 hours straight. I did the arithmetic and it wasn't worth it. Supposedly, there isn't such thing as a "modafinil withdrawal," but I was nonfunctional for about 6 weeks after I left it cold turkey. Not only that, but because I wasn't aware there was a withdrawal phase, I thought my symptoms (not being able to wake up, narcolepsy, nausea) were an ominous sign of an underlying disease.
Yikes, are the effects still lingering? Have you returned to baseline energy/focus?
That was four years ago, and I was back to my baseline self in about two months.

A month ago I was diagnosed with severe apnea, and since starting treatment I feel like a different person. I wonder whether the apnea was worsened by modafinil four years ago, and that was the reason for my constant wearing down. Maybe I'll do an experiment just to see, but I don't need stimulants anymore to be productive, not even coffee.

Isn't modafinil/stims a treatment for apnea?
I believe you're thinking of narcolepsy
Taking modafinil daily, especially for that amount of time was not a wise move. It's a uniquely "safe" substance but even the most avowed users stress not to take it daily even if for nothing more to preserve perceived effectiveness.
Every study I've seen of Adderall (and amphetamine analogues like bupropion) says that it really does improve focus and productivity, even in non-ADHD users.

There are two big hurdles, granted (apart from side effects). One is how long-term toleration works - users report continued efficacy, while objective tests seem to suggest decreased sensitivity. Two is how amphetamines mix with intelligence; normal-IQ users appear to have unchanged or worsened performance on intelligence tests despite 'feeling smarter'. (The same goes for Modafinil.)

But neither of those things really challenge the core observation: in the short term, Adderall and similar substances improve attentiveness, focus/willpower, and probably memory.

They often aren't worth it, and non-medicinal use is often unsustainable. But if someone is showing up with "brain fog" and underperforming while feeling skilled, that really sounds like something else is up. Either a paradoxical reaction to the drug, or some substance other than core focus/'smart' drugs.

edit: I just looked, and paradoxical drowsiness is a known response some people have to amphetamines. I'd bet that the person you're describing has an atypical response to amphetamines.

IME the paradoxical response has more to do with tolerance. I’ve never met someone who sidn’t get stimmed out from amphetamines when they didn’t have a tolerance.

But if tou take them wirh a tolerance and your underlying physical body is fatigued, it becomes very, very easy to fall asleep (or worse, to be too stimmed to sleep but too tired to be productive)

> But if someone is showing up with "brain fog" and underperforming while feeling skilled, that really sounds like something else is up.

One of the things that sustained stimulant abuse contributes to is sleep deprivation and the disturbance of sleep patterns. "Brain fog" - confusion, problems concentrating, memory problems, are all symptoms of sleep deprivation. Sleep deprivation experiments have also consistently produced psychotic symptoms (hallucinations, paranoia, disturbed/unusual thinking - the person undergoing the psychosis of course thinks they are doing fine) - the earliest experiment I am aware of being Randy Gardner's[1] in 1964. "Stimulant psychosis" is supposed to be one of the effects of amphetamine abuse; I think the psychosis is likely due to the sleep deprivation involved in multi-day binges.

[1] https://en.wikipedia.org/wiki/Randy_Gardner_(record_holder)

Wow never made this connection, very insightful observation.
> There was a story on HN with people trying to microdose on LSD, and the alleged benefits - long story short, when they asked peers about their performance, they noticed they're more distracted and not more productive, while those doing the microdosing thought they're on a super productive trip.

This aligns with my experience. Microdosing is good when you have physical tasks to do (i.e. running around town all day, reorganizing / cleaning your house), but focusing on creative tasks is harder.

Tbh, the only thing I'd recommend it for is for people struggling with chronic depression or anxiety - for these two, it can be a life-changingly effective "aspirin" (i.e. not a cure, you still need to fix the underlying causes) without the significant side-effects of traditional medication, and any lack of focus is massively offset by relieving the brain fog of depression/anxiety.

There was a book about systematic drug use in Nazi Germany called “Blitzed” that is worth reading.

Meth was extensively used in the German military and probably contributed to the victory over France. Basically to can stay awake and endure, but cognitive ability is impaired in some ways.

This sounds kind of in line with the theory that drugs are kind of a zero-sum game. You got a lot of speed earlier on and achieved a ton, but then paid for it later on. Kind of like a, "no such thing as a free lunch" economic theory, but for drugs! Not to knock you or your methods, just an observation.
I look at it as a loan. You're borrowing a little of tomorrow's (good mood, productivity, energy, etc. etc. depending on which drug it is) to use today, but you'll eventually have to pay it back with interest.
> a no such thing as a free lunch theory, but for drugs

There's some reason to believe this is literally true - and true in the same sense as the economic rule! In this context, it's been nicknamed the Algernon argument. Gwern (of course) has the canonical writeup.[1]

The short version is: "if some chemical change could make us smarter, why wouldn't it already been in place?" Or, framed differently, "why would the brain evolve to benefit from a chemical it doesn't normally have?" This argument doesn't say cognitive performance enhancement is impossible, only that there has to be some tradeoff for it or we would have evolved it already. If we're going to get rewarding "brain boosts", we need to find tradeoffs that are more appealing than they were historically.

One simple possibility is this one: we can find chemical supplements that let us rearrange when we're performing well, without net gain. Caffeine is an obvious example: it doesn't actually diminish the value of sleep, but postpones the feeling and helps us manipulate our schedules. Amphetamines might be a more extreme case of the same, 'borrowing' energy more generally and paying for it later.

The other dodges are less relevant here, but a fascinating read if you check the article.

[2] https://www.gwern.net/Drug-heuristics

One of the obvious ones is consuming excessive amounts of nutrients scarce in the ancestral environment. Like, you evolved in a place where you can't just buy Choline supplements, so "you're smarter but run out of Choline" isn't a thing that comes about.
Yeah, certainly true. I wish I had summarized more of Gwern's take, because he goes into piracetam + choline as a specific example. His take is that it doesn't violate the rule, but provides a case of a changing environment - burning choline for minor cognitive improvements is a vastly better deal than it was in a choline-scarce environment.
This is a fallacy. There are many things we can accomplish through medicine, or technology more generally, that evolution never could. There are reasons other than it being a net disadvantage that evolution may not have produced something; for example, a particular chemical may not have an easy and cost-effective way to be created in the body (particularly when food was much harder to come by), but be easy enough for us now to synthesise.
Your argument doesn't make sense to me. If the chemical is harder to synthesize, then the receptors could be more sensitive, or bind longer. Why would our bodies evolve to use a messenger molecule that was so prohibitively expensive to make that we couldn't make enough of it?

These drugs are just changing the balances of existing pathways in our brains. They aren't creating new pathways. Either they are causing a substance that your body naturally limits to exist in higher quantities or lower quantities, keeping a messenger molecule from being removed as fast as it would be normally, or removed faster than normal.

So I agree with the parent, it is likely we can choose the tradeoffs, maybe needing to avoid predators and scavenge for food is not our priority anymore and we can turn off some of that so we can think more deeply. But chemically I doubt we can improve ourselves without any drawbacks.

But yes, technology in general, physical things, can have a more pure benefit, and we are already reaping the rewards of those benefits. A new macbook pro is likely to make me more productive while not interfering with my sleep :)

A net benefit is when we can synthesize drugs to allow us to adapt to externalities, which produce fewer side effects than benefits. Vaccines are a net positive in the presence of Polio. It could be argued that stimulants are a net positive in the presence of having to stare at a glowing rectangle and think in abstractions all day.
The Algernon argument is concerned with our inability to make simple, tradeoff free improvements to performance. It says that if you find an improvement, you should be able to explain why it isn't a free lunch. None of those examples make it a fallacy - there's a reason I ended with "The other dodges are less relevant here, but a fascinating read if you check the article."

Gwern outlines three general ways to work around the Algernon rule:

1. We can live under different conditions than evolution prepared us for

2. We can optimize for different goals than evolution rewarded

3. We can make major/multifactor changes unavailable to an local-maximization algorithm.

Condition two is easiest: caffeine is a sensible response to electric lighting, while staying awake long after dark was largely unhelpful in our evolutionary past.

Condition one is sometimes rewarding: piracetam shows efficacy with choline supplements, because we can massively overload a relatively scarce chemical. Other kludges may exist, like boosting immune response by simulating a summer day/night cycle to signal "safe conditions, energy is cheap now".

Condition three is incredibly hard wrt to the brain. It's obvious for the body - eye surgery can improve on 20/20 vision - but I don't know of any drastic better-than-well interventions for the mind.

Could it be that one reason we use chemicals to "enhance" our brains is because we are living in ways we aren't intended to live? Human beings aren't made to sit in front of a screen for 16 hours a day. We probably shouldn't be as isolated as we can get, we shouldn't be living the way we live (in crowded cities, say, disconnected from family or community, doing one thing--coding, for example--for 10 hours at a time, etc.)Does that makes sense to anyone?
I instinctively like these arguments but I think we should be careful about indulging them. A big part of the human animals biological advantage is just how damn versatile it is. The range of diets, climates, and lifestyles which we tolerate is vast, compared to other animals. Different permutations may produce different outcomes in terms of happiness, health/longevity, and so on, but I doubt that you could find some particular permutation that is "the right one."

There is one version of this idea that I like though, which is that I doubt that we're built for 8+ hours a day of intense abstract reasoning, which seems to be what the modern information economy demands of those aspiring to a middle class or better existence. The vast bulk of humanity did not earn their daily bread this way for most of human history, so I don't think our brains are adapted for "abstract reasoning above all else."

Nor for non-movement and staring at a glowing rectangle all day while doing the intense abstract reasoning. We have all sorts of natural mechanisms in our bodies to produce reward chemicals that are not used at all in our lifestyles.
That's what I'm thinking (as I stare at a computer screen for 8 hours...)
I don't think this type of thinking is very productive - it's a romanticization of an ancestral past. The ancestral environment is useful for context for why things are the way they are, but it tells us nothing about the future. We can point back to the habits and lifestyles of the past and imagine cargo-culting their behavior will grant us the outcomes we prefer, but there's no understanding in it. Various communities even implement this, with varying success - see the Amish or Mormons.

As an aside, drug use was extremely common among indigenous peoples all across the world. I don't even think this naturalism fallacy supports these particular claims.

I think it depends on exactly how the question is framed, yes.

It's very useful to recognize when we aren't 'made' for something, because it implies we can get benefits from either avoiding it or supplementing our performance at the task. When we are "made for" a task, like walking for long periods or throwing objects with good aim, it's tough to improve on human baseline. (At least, not without serious side effects. There's a reason drugs to boost strength and physical endurance tend to be risky.)

But that distinction has to be kept separate from a values judgement. As I mentioned in another comment, "reading a good book" is something I'm not evolved to do. That might mean I should be prepared for challenges with the task (e.g. back pain if I sit for too long), but it's unrelated to whether I want to keep doing it.

The 'ancestral environment' stuff is likely to be easy or optimized-for, but that's not the same as being a better way to live.

Yes - this is one of Gwern's big points.

There shouldn't be any easy way to improve on what evolution tried to do, because evolution would have done it. But there can certainly be ways to optimize for things evolution didn't try to do, like preparing us to do symbolic logic for 40 hours a week or stay up well past dark. And there can be ways to optimize for goals evolution didn't/couldn't reward, like "never having kids and staying healthy until age 90".

I do think there's risk in blurring the moral point with the practical one, though. I'm not particularly evolved for reading books, but it's something I enjoy and I want 'hacks' to do it better - whether that's reading glasses or a cup of coffee. I don't like commuting while tired or being stationary for hours on end, and if I had free choice I'd stop doing those things instead of hacking myself to be better at them.

But in "enhancement" terms, they both count as "doing a thing I wasn't made to do" regardless of whether I want to keep doing them.

> why would the brain evolve to benefit from a chemical it doesn't normally have?

You could apply the same logic to Aspirin or any medicine - if reducing swelling was beneficial, why doesn't our body do it for us?

That seems like a misunderstanding of evolution. It's not a master plan driving toward perfection. Our biology is a bag of traits, some of which were useful and some of which just haven't been selected out yet.

I think it applies to aspirin too. You thin your blood, reduce some swelling. You feel better. But maybe you don't heal as quickly. Instead of being immobile and allowing resources to gather at the wound we get back to our work. But our work is leisurely these days and we probably don't need to heal quickly.

Perhaps if you are a runner and you take these seemingly benign medicines to reduce pain and swelling, you end up causing more permanent damage by continuing to run when you should not (I have experienced this).

I think a lot of medicines work by turning off or on processes that are important but inconvenient at the time. Painkillers are probably the best example. We shouldn't take them when we are healthy, it would be dangerous. Other medicines, such as antibiotics, work by killing pathogens directly and don't affect our bodies like the drugs in this discussion.

Yes, thanks for this.

It's I suppose possible to hit a simple optimization evolution hasn't found yet, but that's rarer than people seem to think. The major examples we have are either things which evolution lacks the tools for (e.g. mechanical prosthetics) or major biological leaps (e.g. your antibiotic example).

The things that look quick and easy like "eat some willow bark extract" have tradeoffs, even when they aren't obvious. Taking 'painkillers' to the extreme - morphine - makes it especially obvious. It's generally a terrible idea unless you've recognized that there's a problem and gotten someone else to take care of keeping you healthy while you're out of commission.

> "why would the brain evolve to benefit from a chemical it doesn't normally have?"

That's the thing, that's not how it works

The brain didn't evolve to be affected by substances unknown to it, it's plants that evolved substances that have CNS effects. (Though the body did evolve to depend on a lot of external substances - be that calorie and protein sources or vitamins)

Nicotine is literally a pesticide (and yes, people do use it as such in some occasions). Not sure how other substances evolved though (I think caffeine made the coffee seeds travel further)

Our brains exist as an adaption to allow us to survive long enough to procreate. We did not evolve a brain to work harder, smarter or faster. The fitness function for evolution is not intelligence, it is survival and procreation.

It does not follow that evolution would maximize intelligence or performance.

Human intelligence exists as a by-product of many cumulative adaptions for survival.

Caffeine certainly is a good, tame example. It's chemical effect is basically to block your brain from fatigue signals, perhaps analogous to anesthetic that blocks pain signals. It doesn't actually prevent fatigue, just as anesthetic doesn't actually prevent injury or damage. You are still burning through energy and accumulating sleep debt like anyone else.
The analogy I like to use is "buying on credit" - you can choose the time and place of your enhanced productivity, but you pay for it later, with interest. You're not actually creating any new productivity, just shifting it around.
I think it is more a sprint vs a marathon. Many people don't ease into drug usage nor do they try and follow any way to actually tell if they are getting any gains from it. We see this in all aspects of life specially in sports where athletes might actually hurt their performance because they start doing something like some oddball workout that is suppose to improve you or by working out more to try and get gains. Without data, numbers, and a third party watching you then you have no sure fire way to tell if you gaining anything from drugs. People abuse them hard starting out thinking they are a silver bullet, then burn out fast.
> I remember a CEO of one of my early startups would give me 5mg addies to help me get more done.

That person ought to be in jail. A CEO is definitely not in charge of the pharmacy, anything of this kind should be prescribed by your doctor.

Even though the entire ethos of my comment suggests that you wanna stay away from this stuff ... occasional/recreational use is not a big deal. He never pushed it on me, it was just something that I could take advantage of on occasion.

I don't look back on it and think it was predatory or a big deal or a malicious thing. I definitely don't think he deserves to be in jail or punished.

The guy is in a power relationship with his subordinates, he is definitely not the one to go and prescribe medication. The best thing he could have done is to send you to a doctor.

If a CEO here in NL suggested I take some pills in order to improve my productivity and offered to supply them my first step would be to inform the board in writing and my second would be to resign my position. This is simply not ok, and not acceptable.

>If a CEO here in NL suggested I take some pills in order to improve my productivity

I'd agree that it's not professional/ethical, but the OP didn't say the CEO suggested it.

For all we know, poster might have initially asked (Of course, agreeing to hand out arbitrary medication is of course not the right answer).

Who the hell would ask their boss for drugs?
I dunno, maybe the CEO was open about using the medication for productivity reasons and both folk had a laid back attitude to the subject?

Point is I'm trying not too read too much into their dynamics and make assumptions based on a short HN comment.

It says 'to help productivity' which to me sounds like a benefit to the employer more than to the employee, which in turn suggests which way the flow was. That could of course still be wrong.
This conversation reminds me a little of the Vernor Vinge novel A Deepness In The Sky where the antagonists subjugate their conquered/enslaved foes with chemically-induced “focus” in order to improve their productivity/output. Explored is how this arrangement is not unambiguously good for the employer nor unambiguously bad for the “employee”.
Not that it makes a difference completely but I have a feeling the employee was 22 and the CEO was 24
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These moral fiat statements are unhelpful to no one. You simply don’t know the context. In a very flat power structure or a very small company (2 to 3 employees) at the office, social dynamics change dramatically.

Never mind that caffeine is legal yet it’s the shittiest productivity drug I can imagine yet everyone is falling over themselves to serve it to you and get you one while they’re out on break. I’d much prefer people ask me if I’d like a pill of modafinil to the addictive cranky horror that is caffeine.

> These moral fiat statements are unhelpful to no one.

Nice to see we agree.

> social dynamics change dramatically.

I'm sorry, but whatever the 'social dynamics' as a person in a position of authority over another there are some lines you should never cross. Not knowing what your mandate is as a CEO is a recipe for disaster.

If an employee has a productivity issue a CEO does not have mandate to prescribe - or even suggest - medication. The fact that that needs spelling out is worrisome.

Beautiful story WhaleSalad! God bless you man.
> I remember a CEO of one of my early startups would give me 5mg addies to help me get more done.

Jesus. If that happened to me, my first stop would be to the board/investors to report it, and my second would be out the door and to a new job.

> It's only way to do some of the things that the really successful engineers are doing. You forgo eating, exercise, etc... and spend 110% of your time on working and chasing the high of getting shit done.

I suspect your belief of the effectiveness here is quite a large exaggeration. You might have tunnel-vision focus and the ability to stay awake for long stretches and work, but the quality of that work just cannot be top notch. If you don't eat, exercise, or sleep much, your brain is not getting the fuel it needs to work properly, and no drug can replace or mimic that. Over the (very) short term you'll see a benefit, but after that it's just vapor.

I won't advocate the abuse of any particular drug, but I will say it's not as simple as trading quality for focus. There is a margin of overhead that comes with poor focus, so sharpening can lead to improved productivity without loss of quality. To a point, after which your comment applies.

I'm saying this not to say "Actually..." but so that no one discounts your valid point just because they have some anecdote where it didn't apply. There is a point where you pay (or at least stop winning), and our understanding of where that point is and how stable it is is very lacking. Likewise, our judgement under the influence of something should not be considered 100% reliable. Neither should our judgement NOT under the influence, but people tend to become zealots when defensive, and fewer people are defensive of being "normal".

I had a friend that I was discussing nootropics with - It's a topic I'm very interested in, but I'm not interested in any notable experimentation because, well, I've only got one brain and our understanding of it is pathetic. His answer was that by experimentation you'd discover what worked. We were definitely coming at it from opposite ends despite similar interests.

Anecdotal, I know, but I've heard of this at two companies. One of which jokingly put them in Pez dispensers.
> Now I am 100% drug-free and am not at the same level I was back then

It pains me to think the abuse left permanent damage.

What kind of food do you eat on a "clean" low carb ketogenic diet?
You never had full blown ADHD so you literally were getting high off stims and pulling through insane hours. Amps make the ADHD brain feel baseline normal to that of neurotypical brains.

Congrats on kicking the pills.

I have a similar productive output currently as you described your amped up self to have and i drink 2 (sometimes 3) coffees a day. I get 1-2 hours cardio in 4 times a week and i spend time with my family. I sleep 7-8 hours a night. I take at least 1 day a weekend off completely.

Pills wouldn't help in fact they would make it more difficult. Organisation, ruthless priorization and discipline are the key. The rest is just distractions.

A lot of people experiment with various psychedelic drugs for the psychedelic purposes. Marijuana is pretty much normal. LSD is sometimes used in the form of microdosing that produces no psychedelic effects and should improve focus and creative thinking. And of course coffee and alcohol are abused hugely.
And MDMA.

I've heard a fellow engineer say, "it lets me enjoy being an extrovert."

Yeah, forgot to mention that one, very true.
Can you work better on ecstasy though? Isn't that more a recreational thing than a productivity related thing?
i find psychedelic experiences to be very beneficial to productive states if you wield them properly, and stimulants often do help with focus and efficiency when it comes to working, so, i could certainly see MDMA having some very beneficial neurological effects during the course of the experience.
I’m perfectly agree with “Neurological” effects on MDMA.
I found CandyFlipping - First LSD,4hours later Molly, is one of the best combination for coding. It gives you a very strong sense of color.
Yes, I've been reading about psychedelics. But that seems to be more to spark creativity (and there also appears to be some actual therapeutic benefits to it). Whereas opioids or stimulants seem to be used for different purposes.
Sure. LSD is very special because it actually helps to focus more as well as increases creativity (if we're talking about microdosing). Stimulants and opioids are not really that common. High quality cocaine can be seen but it's not really "normal" like the other drugs are. Meth, crack and heroin are hugely frowned upon, it's a failure to be a user of these. MDMA and LSD have very different effect based on dosage. It's entirely possible to work (better than normally) on small doses and of course it's purely recreational in bigger doses.
And the drugs that are frowned upon... that's (as far as your experience goes) in the tech industry? I know lawyers that had meth addictions. Peter used coke, adderall and meth. It sounds like cocaine is more widely accepted (and perhaps legal stimulants like adderall, ritalin, concerta, etc.?)
Yes, in the tech industry, and all of it is of course only my personal experience. It's seen as a failure to get addicted, so these highly addictive substances are out completely. They also don't really give you anything apart from problems (compared to other drugs). Cocaine is seen as somewhat OK but uncommon because it's hard to find cocaine that is of OK quality for an OK price (you definitely can't buy that on the street) - and again, addiction is a failure. Some people fear legal stimulants more than they fear LSD; but they're definitely pretty common (especially within student groups) and not frowned upon at all, I've seen people have (not prescribed) Adderall placed visibly on their desks.

Being visibly influenced by a drug is a huge failure as well. It's OK if you take and it's not visible but once you act differently (e.g. talking too fast, slightly jumping around while standing etc.), people will think badly of you and you will be a target of jokes. Having a different behaviour even if you haven't taken the drug (e.g. if you get cravings for it) is seen as bad too.

Modafinil is a hot topic these days
Peter said he thought he needed modafinil. Why is it a hot topic now? His thought way back was that it was everything he needed at the time--mood regular, stimulant.
It said to have characteristics of a holy grail stimulant: increased performance without the crash or heavy tolerance build.
That’s an odd assertion to make when the full pharmacodynamics and mechanism of action are unknown. Modafinil doesn’t increase your cognitive performance in the way that a substituted phenethylamine would. Focus and attention are certainly related to wakefulness, but wakefulness in and of itself doesn’t increase cognitive performance.
Can you tell me what substituted phenethylamine is?
Substituted phenethylamines[1] are derivative compounds of phenethylamine. Many substituted phenethylamines are stimulants, while some are psychedelic too. Dopamine, epinephrine, amphetamine, pseudoephedrine, MDMA, and many others are considered to be substitued phenethylamines.

[1] https://en.wikipedia.org/wiki/Substituted_phenethylamine

it's heavily dependent on the right genetic makeup from what i know.

for some it provides clarity, for others, fog. the dopamine transporters are very mysterious to me.

No crash might be the problem with it: you try to go to sleep and end up just kind of laying there half the night.
Modafinil interferes with sleeping less than other drugs - it's only a problem if you rely on the "crash" of running out of energy over the day to fall asleep.
Yup. I used adrafinil(prodrug of modafinil) regularly during university and found it particularly useful in my programming classes. It helped me get "in the zone" while avoiding the euphoria, BP issues, and recovery periods/withdrawals that stronger stuff does. Plus it doesn't show up in most drug tests.
Do you still use that now? or other stimulants? Or did you find you didn't need it after college?
I don't currently use it or other stimulants because I'm recently graduated, currently unemployed, and looking for work. Well I suppose I take caffeine, but I've mostly cycled off that too, and only take a single 200mg pill per day. If I get a job that requires a steady flow state or a high amount of productivity, I very likely will begin using it again.

I use it because I am not naturally suited for the work. I have a genetic variation(gs224) that makes me tired all of the time and stimulation-deprived. However in our current economy, it seems like the only career path I can take that will work with my abrasive, likely autistic personality while still providing long-term career growth opportunities.

It sounds like you would need a stimulant of some sort, just to counter the genetic issue. Thanks for your candor.
When it comes to programming, I think I've found that modafinil (and doubly so for something which must be metabolized first) is not as helpful as I used to think it was. My problem tends to be getting started; but once I'm started, continuing is relatively easy. So for my purposes, a bit of nicotine gum is just as useful: cheaper & legal, doesn't last as obnoxiously long as -afinils do, and doesn't require as big or long-lasting dose. I've often wished for a modafinil which had a half-life of half an hour or an hour...
I generally agree except that it seems to be a huge migraine trigger for me, so Ive stopped using it.
In my experience that’s dehydration. Modafinil is a diuretic, and appetite suppressant. Not only are you taking on less water because you’re probably eating less but your body is expelling water at frightening rates.
That may be true to some degree, but I have also had them happen while purposely chugging water. My migraines are kind of cyclical as well. Could be coincidence.
It's that or I think a lack of choline can also cause it. Cheapest and easiest solution is to eat some eggs.
i may have a somewhat atypical story and experience to share with you as i was certainly a heavy user of mind altering substances during the period of the past where I was a white collar software engineer. ive sent you an email about it, hopefully we can discuss it there. but all that aside I am madly interested in the potential output of this project as it has strong relevance to my individual life path.
I will be checking that email too, later today, and will respond. Thank you.
A lot of weed and alcohol. People more curious than that will try LSD, schrooms, DMT, cocaine, Exctacy and MDMA. And pretty much any other drug they come across, at least once, except opiates. Never met anyone in IT doing opiates as far as I know (could be wrong). That is my experience amongst colleagues under 40 in the IT industry. Doesn't differ much from the other industry I've been in. None of these people have been effected by their weekend sins much besides hungovers and a thinner wallet.
Glad you're looking into this.

As a counterpoint: I've been a developer 10 years. I've worked at a few established businesses, two startups (one U.S. based and one German), and two consultancies. I worked in-person in Charlotte, N.C. and remotely since then. I've never worked in Silicon Valley.

One employer had a "play hard" culture, encouraging alcohol (ab)use outside of work. I didn't stay there long.

Perhaps I've self-selected based on my values (I don't work overtime), but I've never heard drug use condoned in any of those places, or at conferences I've attended. And I've often heard overwork spoken of as counter-productive and exploitative, as a thing that wise coders avoid.

I was not aware that "drug use as a programming aid" existed in the industry, though, human nature being what it is, I'm not shocked.

Just a caution that this shouldn't be portrayed as if it's ubiquitous without statistical evidence of that.

Yes absolutely understand that. And I'm coming at this as someone trying to learn what the situation is--I don't have a preconceived notion of stimulant or amphetamine use as being pervasive. That's why I'm here--to learn. Thanks.
I'd like to echo nathan_long's sentiments.

I worked for a small startup in Atlanta from 97-2000, then another startup in Silicon Valley from 2000-2004 (yay dotcom boom -- I slept under my desk more than once). I relocated to NC in 2004 and continued to work for that company (from its newly acquired NC office) till it was acquired by HP. I remained at HP a couple years. In 2009, I joined another SV startup (my third I guess) and worked from home for that startup till it was acquired by Yahoo in 2013. I've been at Yahoo, now Oath/Verizon since.

In all that time post-college, I've never used any form of drugs (besides occasional alcohol either outside of work or at a company party, beer bash Friday, etc), never felt any pressure to do so, and I've not been aware of drug use by colleagues with the exception of one person, but even that was hearsay to me.

Some of the stories I read about SV, I wonder how I could be missing so much (see for example, "The Nudist on the Late Shift").

That said, I tend to keep to myself. For me, work is work, and play is play, and I'd rather not cross the lines.

46 y/o, highly compensated software developer, married, father of two, used marijuana recreationally in college (I have a funny federal security clearance story about that...), never used any other drugs besides one not so good evening with LSD. Long distance running is how I keep my head straight, besides getting enough sleep and a relatively good diet.

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a problem for me, as a reporter, is the lack of statistical evidence of any kind for this. It's very difficult to get an accurate portrayal of the problem based on surveys that would require self-reports. That's why forums like these are helpful in informing my reporting.
Yep, I understand you can't easily get stats on this. I just didn't want you to hear exclusively from one side.
There are reports of cocaine being detected in waste water (1). You could approach water companies to see how granular their data is. Perhaps you can see that there are peaks of coke in the sewers near Wall Street or Madison Avenue.

[1] http://www.independent.co.uk/news/uk/home-news/cocaine-use-i...

You'd probably just get a heatmap where there is little use of water. i.e. a single individual doing cocaine in a suburb would show far greater concentrations than 100 people doing cocaine at a rave at some farm that's irrigated on a daily basis, or 100 people doing cocaine at a wall street office party above a bunch of laundromat companies.
I definitely fall on this side of the scale. I've certainly heard of people using "performance enhancers" in a programming context, and have seen hard drug use at parties (very infrequently), but it was never my thing (hell, I don't even drink coffee), and none of the people I know well and consider solid developers have a drug habit.

I think -- and this cuts both ways -- people into the drug scene naturally gravitate toward others that are also into it, to the point where they think "everyone" does it. I suspect tech's drug problem isn't markedly larger than society's drug problem as a whole; it's perhaps smaller considering knowledge workers get paid based on how well their brains work, and long-term most drugs seem to mess that up.

I'd love to see a concerted effort to study the prevalence of this sort of thing. It's frustrating that I can't validate my expectations here.

I would love to see a study too.
Working in the valley for the past 10+ years, I've pretty much had the same experience as you. I'm sure in some circles overwork and drug use on the job are the norm, but certainly not everywhere.
I know lots of people do pot.

Don't forget the alcohol!

What about other kinds off addictions like porn?

I wanted to mention this as well. Porn is the one that mostly gets away in these discussions. It kills motivation, enhances anxiety and depression over the long term. And these are just first order effects. It can easily affect your relationships, work and personal, and make you numb. It's something with limited upside, that feeling of ecstasy when orgasming which has been reported similar to that of heroine. But that is short lived. Other than that there are only downsides.

OP If you're interested in the topic, I'm happy to go deeper into the subject.

Scott Alexander has written, in the past [1], about acting as a gatekeeper for people who want Adderall. Could be worth interviewing him?

Gwern Branwen is also quite open to talking publicly [2] about his experiences ordering things like modafinil without a prescription.

[1] http://slatestarcodex.com/2017/12/28/adderall-risks-much-mor... discussed https://news.ycombinator.com/item?id=16033574

[2] https://www.gwern.net/Modafinil

appreciate this, thanks.
I am open to discussing this in raw detail - contact in my profile.

Most programmers, scientists, people in finance and startups I know take a lot of stimulants. I take a lot of stimulants.

[Edit - as others have pointed out, there's a strong selection bias going on here. I actively seek out people who I know take stimulants, and we naturally congregate socially based on a bunch of subtle and explicit cues that signal we are safe to talk to about this kind of thing. My experience is not a random sample - I'm just responding to the request in the OP]

I have pretty severe ADD, so I take ritalin. Initially it was on prescription, but then I realised it was actually easier and cheaper to just get it from other sources.

I was pretty productive before because I developed a bunch of working practices that mostly contained the ADD, but with ritalin... I feel superhuman. And to be honest I can output an order of magnitude more and better than most people when I'm up. I recently moved to Berlin, where everyone is up all the time. Like, I know people who founded or are working for hundreds of businesses. Everyone, every single person, is up all the time. Adderall, dexedrine, ritalin, plain old speed paste, cocaine, kratom, modafinil. LSD or MDMA microdosing. Everyone works best when they are up. Then on the flip side, xanax, zopiclone, diazepam help control the wiredness and allow you to sleep when you want. Everyone is doing this. I know it's the same in London and New York.

If I have a good week, I generally will take perhaps 30mg Adderall IR a day, or 50mg Ritalin IR. If I need to brainstorm or deliver something with someone we order whatever (stimulants are delivered within 15-30 min by taxi here) and work through the night to get stuff done. This is normal. It's strange to me to see this being described as a problem because... it's not a problem. It is fairly low risk (compared to e.g. binge drinking) and it completely transforms your ability to work. It's so normal to me that I don't hide it from anyone and nobody ever complained. I meet random people, like undergraduate students from the USA who are visiting, and they are in exactly the same routine. Everyone works best with stimulants.

I'll contact you directly, and appreciate your candor. Do you think it's a European vs. American thing? That we tend to demonize in some ways the need for substances to help us in some way, whereas in Berlin, for example, no one cares? And they've schooled themselves so that they know how to use it 'safely'--whatever that means? surely taking this stuff in the long term has some effect on the body (not sure if the effect is necessarily degrading in some way, but it must have an effect, at least on the liver...no?)
My understanding from my American friends and partner is that it's exactly the same in the USA. Students, software developers, people in finance - for all of them stimulants are normal. I think most people aren't really concerned about being safe - the assumption is that because everyone else is doing it and nobody is getting hurt, it's safe. Which is mostly true (the jury is still out on the long term effects, but for pharmaceuticals the risk is miniscule with normal dosages).

Edit - I will say though that Adderall and coke are by far the most common for people from the USA. For whatever reason those are definitely the North American drugs of choice in my sample.

seems to be what I'm finding too, thank you.
Addy / Vyvanse seem to be the doctor's choice (as well as college kids') so it is generally just more available and seen as safer than straight street speed. Similarly, coke is also much cheaper / readily available in the US compared to Europe. I don't / have never opened up to coworkers about drug use/abuse but among my high earning friends, I'd say its a small group that uses it frequently and a large group that uses stimulants recreationally or when there is a big deadline coming up. I fall into that second category - if I have a ton of work and access to addy I'm going to be using it (I can't ever concentrate on work on coke - tons of energy and concentration, just no interest in doing work). However, if we're talking weed it's well over half of my friends that use it daily usually in the morning while answering emails / prior to work and immediately after / while working late. Granted, those same friends that smoke daily have been doing so since college
Why weed? It would seem that would make you want to hang out all day and snack, or just sleep or watch television?
We just love weed? For me putting a little tincture in my coffee in the morning is the perfect combo. The weed takes the slight edge off my massive mug of coffee so I get the energy but not the cracked out feeling that lots of caffeine can give you. Plus, answering emails is boring as fuck, I'd rather have a little buzz when I do it. Also, some of my best code was written while high at midnight the night before a deadline.
> My understanding from my American friends and partner is that it's exactly the same in the USA. Students, software developers, people in finance - for all of them stimulants are normal.

This is patently false, and I think your assumed universality of drug use is based in no small part on your use, and the crowds that you've associated with because of that drug use.

I certainly know some people who've used stimulants from time to time (SF bay area), but that's the rare exception, not the rule. I know some people who have used MDMA, cocaine, etc. at parties, but it's not many. And, being in SF, I of course know a ton of people who use marijuana regularly.

I'll accept that drug use is probably higher than what I see (I have the opposite problem with perspective: as a non-user, I tend to associate with non-users), but suggesting it's the norm and is "everywhere" is an excessive exaggeration.

I'm not sure what you think I was saying, but I was saying exactly what I said. My friends and partner report that it's normal - obviously in their social circles. I'm not making any claim about wider society. You quoted the word "everywhere" but I didn't use that word.
You said:

> Students, software developers, people in finance - for all of them stimulants are normal.

That's absolutely untrue. For certain (very small) subsets of those people (well, software developers, at least, which is my main area of experience), it certainly happens, but it is definitely not normal.

I lived in London for a few years to work in finance (top tier banks as well as hedge funds). I haven't met a single person who takes any sort of stimulants besides coffee. I'm a software engineer myself and your world seems very different from mine despite having worked in the same city. Your normality looks completely foreign to me.
Interesting! That is... really quite surprising to me. I don't know many people anywhere in the world who don't at least recreationally take drugs. I think perhaps we just inhabit different worlds. One thing I can promise you though, is that you do know people who are taking stimulants. They just aren't telling anyone :)
I have to say I agree with 'stzup7. I work in finance in NYC; it's a high-money, high-tech, high-drinking environment. I have coworkers that work too hard. They're not taking anything more than coffee.

I know a couple of people outside of my field who are taking stimulants and talking about it. I know a couple people within my field (and outside) who take drugs solely recreationally, not as a performance booster or a way to get to sleep or anything, and certainly not on a regular let alone daily basis.

And I definitely know enough people within my field closely to know that they're not taking stimulants.

I think you just inhabit a different world, yes. (And I worry whether you inhabit a world of people who think they're productive; a sizable number of the the really productive and skilled people I know tend to be so clean that they don't even drink.)

Your last point is a particularly interesting one. A lot of the most productive and skilled people I know are also very clean. But a good number of them are also using stimulants.

I think we all inhabit a world of people who think they are productive - in the sense that many people optimise for the appearance of productivity as opposed to optimising for actual productivity or value generation. I can honestly say that stimulants make a vast, objective difference to my work output and quality (but I actually do have ADD so I'm not a good measure). I have also seen many other people produce extraordinarily good work on stimulants. At the same time some of the very best people I know don't need them and wouldn't touch them. We don't all have the natural ability or background those people have, so stimulants are a proxy. Quite probably many people are not achieving their maximum potential simply by using stimulants. Quite probably many people are decreasing the quantity or quality of their output by using stimulants. But objectively (as in, see the scientific literature) they do work. Whether people make them work for them is a different matter.

>I can honestly say that stimulants make a vast, objective difference to my work output and quality

What objective measures are you using to evaluate yourself? are you in the top 1% of earners for your experience level, position, city?

I am not comparing myself to others, but to myself without stimulants. I simply do more and better work, by very simple measures like completing tasks and delivering projects to the satisfaction (or joy) of my clients.
> One thing I can promise you though, is that you do know people who are taking stimulants. They just aren't telling anyone

Yeah, I guess so. I'm also in Berlin, and a lot of people take some kind of stimulant. As someone not taking any stimulants (not even coffee), it was quite hard to spot it in the beginning. At one point I was working with a larger group of people and only after a few months I was told that more than half of them were on some kind of stimulant almost constantly.

So how do you spot that?

The closest I came was when I had some papers on my desk that were given out for free somewhere and somebody informed me that that was used mainly for smoking pot. I had no idea.

It's almost an opposite of Hanlon's razor: "Attribute to drugs what you could attribute to lack of sleep (or similar)". That plus physical tells are the biggest indicators. In the end I wouldn't say that could give a definite evaluation if someone is using drugs or not in most cases.
drug people find other drug people because drugs
You have, they just haven't told you about it and you haven't spotted it.
I’m that squeaky clean guy in high school that (unbelievably) never even encountered anyone smoking marijuana back then. My social circle did not and still doesn’t really include much drug use. Yet I’ve directly observed Adderall abuse in Silicon Valley. That’s how prevalent it must be.
what makes you resist going that route? Do you also feel pressure in the profession to work longer, produce more, etc.?
Gray hair helps. I’ve got enough experience at this point where I can be productive without going into “production frenzy.” Lots of the younger folks don’t get that yet and think it’s all about how much code you write or how long you’re at your desk. I like to think of it as the difference between doing work vs “producing evidence of having done work.” There is a lot of pressure to do the latter I think, especially for the junior folks.
In your experience, is there more substance use (drugs, assuming alcohol is used sometimes to excess by all age groups) among the junior folks, because of the difference in the pressure they feel?
That would require more speculation than I’m willing to engage in. I can comment on the various pressures to perform that apply to older and younger tech folks, and why I personally don’t feel the need to go the Adderall route (essentially I don’t think the results of merely more output are worth it). To put the two together I’d encourage you to find people currently going down that route for their perspective. Given the discussion here it shouldn’t be hard to find a few! Good luck.
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chiming in here to corroborate that stimulant use/abuse is heavily prevalent in scientists and startup types that i know.

even the md/phd types who have been in clinical practice for 20 years do it, even after they've had kids etc. most only abuse coffee-- you can tell because the norm is to drink coffee until you're literally red in the face when there is serious work to get done. there are people who abstain, of course. they aren't looked down on, but they're probably not as productive on average.

coffee isn't bad at all. but plenty of others use/abuse prescription stimulants too, usually a bit more clandestinely in my experience. but if you know what to look for it's easy to tell when they're on them.

it makes sense. the point where people need stimulants the most is in synthesizing experimental insights into new hypotheses in light of other literature. it takes a lot of brainpower to keep trucking... you can take a crack at it without stimulants, but you'll run out of steam quickly.

as far as the downside, a handful of people binge drink to come down, but it isn't the norm, except during social events. there are a few who smoke weed / take xanax at work to calm down, but these are frowned upon somewhat.

So is it almost impossible to be a top scientist in your field if you don't get some help so that you can have those epiphany-producing insights, etc?
I... doubt that's true. I imagine there are people who think that this help will help them become top scientists (and maybe we should have a talk about the pressure to succeed etc.). But I suspect that a lot of the actual top scientists are plain good at what they do, and they neither need nor want the effects of drugs in their work.

(Which is very different from recreational use, of course, or recreational use turning into addiction.)

Part of what I'm trying to determine is if that pressure to succeed makes people believe they need something to be competitive. My daughter, for example, sometimes feels like she's at a disadvantage at college because so many of her peers are taking adderall (w/o a prescription) for tests and studying. Is it the same after college, professionally?
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I'm in my last semester of college as a Computer Science student. I know a ridiculously large number of people who use adderall or vyvanse to gain a competitive edge.
Does that make you feel you should be using something too?
No. I think that I would enjoy them too much, so I know I shouldn't participate. Also, I still do better on exams than most of the people I know who use these, so it seems unnecessary.
IME, in academic biology, the answer is generally no. Personally, I do use, but it isn't a result of competition, but rather a desire to achieve the most I can for a goal I care about. I don't feel pressured in any way to make this decision; if anything, the pressure is slightly in the other direction.

The big trouble with it is that a drug -- any drug -- will alter your perception of the world such that it is difficult to know with absolute confidence whether you are taking the drug for purely rational reasons to further your personal goals...or not.

Amphetamines at least, based on my experience and reading of the literature, improve your ability to do huge amounts of light/easy work at the expense of "deep" thinking. This means that they would be most effective for people who are knee-deep in work that is too easy for them and need to get more throughput. Undergrad is exactly this -- tons of relatively easy work. Professional life is not; quality is in the long term valued over shitty quantity.

I hope your article won't be a complete hatchet job on white-collar drug use -- the reality is very complex. Humans in general, and white-collar workers in particular, are living in environments and doing things extremely different from what humans evolved for. Thus, some of us use drugs to tweak our biology to adapt to the situation. Assuming that these do in fact improve performance -- a very disputable assumption -- this would be a success story for human intelligence and adaptability.

I don't want to do a hatchet job on white collar drug use, no. I want to learn what's actually being used, the extent of the use and then draw some meaning from that, meaning that doesn't intend to say whether the use is bad or good but just why it exists and what that might mean about work culture, society, etc. If you'd be open to talking more about this separately, pls email me at zimmermaneilene@gmail.com. Thanks.
I was at Cambridge for 4 years and I can safely say that none of the professors in my department were using stimulants other than coffee. I can clock someone who is up across a crowded room. None of them were ever up. A large number of the ambitious PhD students and postdocs were though, and a very large proportion of the undergraduates. I think it's probably a generational thing. Students sell to students. Nobody is selling to professors, and even if they tried, those people have already achieved their success in a generation of people that didn't have access to these things.

I think we will see a generation of people come into these positions (e.g. professorships) where a significant proportion of them are using pharmaceutical enhancement as one of the many tools in their box. Stimulants aren't magic, they don't make idiots clever. But if you're a clever person who is tired or stressed, they can (seem to) make a big difference.

how can you tell if someone is up? Just from years of using stimulants yourself or are there obvious, telltale signs? I missed a boatload of them with Peter.
Dilated pupils. Tense jaw. Muscles around the eyes are slightly more tense (small wrinkles temporarily disappear for example). People react faster and speak more coherently (or if they took too much, incoherently but very fast). Dry mouth (very slight lisping or tongue sticking when they talk). Straighter back, clenched fists, grasping or fidgeting hands that they don't normally have. A general appearance of alertness. Unusually impressive performance in a social situation.

Some combination of the above, but it's pretty obvious once you get used to it. At the same time, I'm pretty sure many people in my life have no idea that I take stimulants (though as I said, I don't hide it), but just see me as being at my best when I'm on them.

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(Excess) scratching, excess fidgeting. Staring off into the distance in the same direction for a while. Overconfidence and they really like to talk about stimulants ;-).
Flinches if surprised, picks at skin or scratches more than normal (there might be visible sores from this), intense preoccupation with things ordinarily beneath interest, hard to interrupt from work, drinks lots of water if responsible, particularly unconcerned with thirst if not. Particularly prone to discuss subjects at length, perhaps an unusually quiet or loud vocal tone.

There's also of course the side effect list, which usually reflects this sort of thing: https://www.drugs.com/sfx/amphetamine-side-effects.html

> Flinches if surprised, picks at skin or scratches more than normal (there might be visible sores from this), intense preoccupation with things ordinarily beneath interest, hard to interrupt from work, drinks lots of water if responsible, particularly unconcerned with thirst if not.

... is someone giving me stimulants without my knowledge? That's me at baseline.

Or should I cut out even my one cup of coffee per day?

>most only abuse coffee-- you can tell because the norm is to drink coffee until you're literally red in the face when there is serious work to get done.

That doesn't make sense. Being tweaked on caffeine doesn't make you more productive. It doesn't even make you feel more productive.

> a handful of people binge drink to come down

Biologist here, and yep, that was the only real discernible downside to me. Especially when I was new to the drug (Adderall) and didn't know how to time the doses and therefore took them too late in the day, I would get a powerful urge to drink about 3-5 hours after the last dose to come down. However, if you dose early enough in the day you will come down naturally.

Besides the desire to "drink to come down", the other problem is that Adderall will make you feel clearer and more energetic for longer while drinking, making it easier to miss the warning signs that you are approaching (or have passed) the "too much" threshold.

I am not aware of stimulant use being very common among the people I work with, and you are absolutely right that it is easy to tell the symptoms.

Relevant article: https://www.nature.com/news/2008/080409/full/452674a.html

If ~20% of biologists (broadly speaking, and higher in younger cohorts) "have used" a drug to enhance performance, then the number regularly using must be lower, unless there is selection bias in this informal poll, and if there was I would suspect the bias would be towards an overestimate of use, as people interested in the question seem more likely to respond.

Overall, then, I would guess use in these fields is "semi-rare" (maybe 5-10% of the population are regular users).

> there are a few who smoke weed / take xanax at work to calm down, but these are frowned upon somewhat.

I find that attitude hilarious. Rampant stimulant abuse is the norm and is accepted, but combining with another drug to calm down is a no-no? Amazing.

This is, subjectively, absolutely insane to me. In your experience do people have an easy time going off these substances?
Haha, well, I can only assure you that it's basically just fine. Nobody gets hurt. It's just a thing people do - like drinking coffee or energy drinks. But it works better.

In the case of amphetamine-related stimulants (ritalin, adderall, dexedrine, speed), it's easy to come off them if you aren't abusing them for pleasure as opposed to work. There's a level of use that enables effective work, and then another much higher level that makes you feel 'high' all the time. If you get high every day, you might well get addicted. But I've never seen it - I even abused my ritalin pretty heavily for pleasure for months and then stopped cold turkey (by accident), and it was just fine. I was mentally the same as I was before the ritalin, and no side effects that suggested physical addiction. I wouldn't recommend it though, it might affect different people differently.

Interesting. Do you think the drug use is due to pressure to succeed / survive, or because you get more out of your time? Having more productive time is appealing but the idea of working 24/7 makes hanging myself appealing by comparison.
You get more out of your time, but many people want that due to pressure to succeed.

A lot of people think stimulants just keep you going longer. They do that, but for a large number of people they greatly improve working memory, problem solving and systematic reasoning.

I know students that take Adderall because their lives are so complicated that they don't have space for regular studying. So they take an Adderall the day before an exam and cram the whole semester in a day. They ace the exam and don't remember much a few weeks later. Similarly I have seen programmers (and been an example) who have a project to deliver but other stuff going on and use Ritalin or Adderall to pull the whole project out of the bag to the expected standards in a tiny fraction of the time it was predicted to take. And others who use the same to just produce much much more than their peers. And then others who just take stimulants because they think they need them but don't actually produce anything worthwhile, or just end up staying awake too much and being much less productive overall because they destroy their circadian rhythm.

I'd definitely say that if you don't feel you need them, don't take them :)

Keep in mind the therapeutic dose people take to focus better is an order of magnitude lower then the dose people take for recreation.
I was diagnosed with ADD in college and put on Dexedrine. It does an incredibly good job of helping you focus and help you get things done.

I feared the drug though and never took it as much as prescribed. I phased it out completely after a few years and later realized that there are other factors that can help just as much with your attention deficit. Sleep, diet, and exercise are insanely important. I believe a lot of people on drugs for ADD could just focus on these 3 things and effectively cure their ADD. Definitely not all people, I am sure there are plenty that need help, but a lot of the time I see it overprescribed (in my non-medical opinion). Just moving to a low carb diet helps a ton. Sleep helps a ton. Exercise helps you feel good and sleep well. On the flip side, bad sleep habits (like those you develop in college) lead to bad eating habits and bad exercise habits. It's a vicious circle. Stimulants help you avoid those healthy habits with some of the same positive outcomes (at the expense of health).

I think you are crazy though if you think prolonged exposure to these drugs is fairly low risk. You build up a tolerance, you need to take more, and it does have long term effects. It seems like you are in your early 30's so you may have been doing this routine for the past 10. If so, when do you think you will stop? Never? Please talk to a professional about it.

I am in my early 30s and have been using drugs recreationally since I was 11. Thank you for caring :) I appreciate it. I am a professional though, and I am comfortable with my current use. It has been toned down massively since I was younger, and become much safer and more careful. I do agree though that people should be careful. I don't advocate for wanton drug taking.
Wow, a great view into how two people can live probably yards from each other and live in what are functionally two distinct planets.
I live and work in Berlin for years now, working in startups, and I haven't met anybody that (openly) uses anything harder than tobacco or coffee, nor I met anybody who said they knew somebody to do that.

Beer is common after work, once in a while. However, what you describe is definitively not normal. Not that I find that problem, or high-risk, or anything - it's just the fact that it would just surely catch attention if anybody from my work environment (30+ close coworkers) notice somebody like you're describing.

I really don't see any reason you would notice it if you aren't doing it yourself. I connect with people based on it, and I find it easy to spot who is doing it because I've been around it for a long time. But most people in my life have no idea that I take stimulants, even though I don't try to hide it. It's just a tablet a few times a day, nobody notices. And the visible effects at work doses are mild, it doesn't turn you into a raving crackhead.
Have you had your work evaluated by people who are not drug users, to verify if it actually is better?

And what if you're on a team with someone who doesn't wish to use drugs? Are they just cut out of the big ticket tasks?

My work is evaluated by my clients, who as far as I know are not drug users.

Taking stimulants for work isn't a social activity. We don't all get together and swallow our pills. I just take mine every day and I know a load of other people who do. I also on remote teams with people who, as far as I know, don't. It's not like I discriminate who I work with based on it, so people who don't wish to use drugs would not even be aware that I was taking them and wouldn't be excluded from anything to do with work.

with all due respect my friend, and honestly I don't mean to insult you, but what you're describing "drugs are everywhere / everyone does them / everyone works best with them / it's all prevalent and normal" is a bit of a drug addict's mentality.

I have friends who are potheads and they swear that everyone smokes weed and everyone who's ever done something meaningful in their life is because of marijuana.

Not everyone does drugs, and not everyone works best with them, it's not normal, it's not enhancement.

The way I see it there's mainly 2 types of drugs in this case: recreational and performance enhancing. For instance both cocaine and modafinil are drugs, but vastly different in terms of safety, addiction and last but not least - social stigma. If you want more information regarding performance enhancing substances, more specifically mind performance (very relevant in tech sector), I suggest you visit /r/nootropics.
Yes, realized that in the last 20 minutes, when I went to look up modafinil. Do you think that the use of performance related drugs and stimulants are far more prevalent in the under 40 set? Or under 30? than among those working in tech that are over 4o or 50?
My guess is the younger the more familiar with stuff like modafinil. There's growing outrage that at least half of Oxbridge is on it and that it provides unfair advantage against "clean" students. It's also my understanding that in the valley especially where hours are long and nights short, modafinil is the go-to.
I've picked up nootropics at 30, mostly trying to catch up with younger, more energetic developers. Part of it was also because these resources weren't around when I was in college. Part of it is because those of us who have been working several years in a soul draining job often look for other ways to enjoy life and take some risk.
I recommend examine.com for finding science-backed information about nootropics and other supplements. Great resource.
Drop me an email, you can find it in my profile.
I will do that. Forgive me, I'm new to HN. When I click on your handle, I don't see an email. Do I find it somewhere else?
edit: found email info
It's probably easier to provide your email or put it in your profile, many commenters might not want to associate their username with a public comment.
thanks. Will do that now.
The "email" field in your HN profile is not shown to other users. You need to put it in your "about" field if you want it to be public. Many people don't realise this.

(The same is true for you, Eilene - your email address is hidden. If you want people to be able to email you, click your username in the top right of the page, and add it to your "about" section.)

Didn't know it wasn't shown, I've added to the about section of my profile. Long history with dope, happy to share if it'll help you.

edit: I'm a senior software engineer

In no particular order: the use of caffeine, alcohol, cannabis, adderall, and modafinil are absolutely rife in the academic research world.

Postdocs and young faculty, in particular.

For all the same reasons it's used in tech--to enhance productivity? are junior faculty and post docs overworked or are the hours required of them kind of insane too?
Pretty much, yeah.

Postdocs and junior faculty are generally worked to the bone for little money. Postdocs need to crank out papers that benefit the lab, but also advance their own career prospects; faculty need to do the same, as well as write grant applications, serve on prestigious committees in order to look good for tenure review, etc.

There aren't enough hours in the day.

I'm a junior academic, recently a postdoc, and I saw a little bit of ADHD stimulant use among peers, and the increasing popularity of modafanil. Basically just due to publication pressure; in my field assistant professors at a top flight university have to write not one but two peer reviewed books to get tenure. Others go in an orthogonal direction and get obsessed with intense exercise routines, also with the aim of increasing those ~six hours of usable cognitive time per day.

MDMA and cannabis are both quite popular and talked about openly but I think that's more a general reflection of the culture in places like NYC and the Bay Area, where I have personal experience.

Good luck with the book by the way. One word of warning: please try very hard to avoid falling into a simplistic narrative that will contribute to drug prohibition. Criminalization of drugs has, IMO, ruined far more lives than drugs themselves. A former Columbia colleague, Carl Hart, professor in the psych department, has written a lot on this and might be worthwhile as an interview subject for your book. Personally I think he sometimes pushes too far in the opposite direction, but he is nevertheless an important public voice speaking up against decades of scaremongering.

I am not trying in anyway to contribute to prohibition (and history shows it doesn't work anyway). But I'll keep your warning in mind, sincerely. And I'll track down Carl Hart. Thanks.
Just realized I've reached out to Hart but have not heard back.
Of the developers/tech folks I know it's mostly a weed/booze crowd. A few people that do party drugs. And a few people who occasionally do psychedelics. No one I know seems to have any outwardly visible issues with it. I do know one person who I am sure has problem with painkillers, but it's that scary blurry ground between "addict" and "chronic pain sufferer". I don't think it effects her work, but I wonder about their personal life.

Also stimulants. I almost forgot to mention them because they are basically water in this industry. Almost everyone who isn't on some sort of health kick is using some combo of caffeine/amphetamine derivatives/coke/modalert/etc.

do you just steer clear of those using stimulants of some sort (when you say those you know are mostly the booze/weed crowd). Is the reason it's 'basically water' in the tech industry only because of the hours needed? What's the fear--if you don't keep up, do you lose your job? Does your career flounder?
Haven't done anything myself other than smoke weed in the evenings. However at times I've wanted to give Adderal a try to get me through challenging times. When I was in college I used relatively high doses of pseudophedrine during exam times and found it helped me focus. I used it once during finals to stay up for 3 days. I aced those exams.

Currently I am a high level IC at a major web company. The pressure and competition at this level is incredible. I only do this job and put up with the pressure because I need the money (long story) and am trying to put my family ahead. I do like what I do though but would scale myself back if I didn't need the money.

When I get stretched too thin, I have trouble focusing. Adderal would be a way for me to focus when I'm running on fumes. It's not something I'd use daily but something during crunch times for sure. I've not done it because I haven't found a non-risky way to get it. I won't buy this kind of thing on the black market because I don't trust the product or the people. I'm not going to ask my doctor for it. But if I had a reliable way to get it, I'd have it.

Not necessarily endorsing stimulants but here is a good analysis of Modafinil suppliers: http://www.gwern.net/Modafinil#suppliers-prices. It's worth reading the whole page from the start though if you're interested. Includes some comparison with Adderall too.
Also consider Adrafinil. It metabolizes into Modafinil, but Adrafinil can be purchased legally from just about anywhere (Amazon has a few listings).
Adrafinil has side effects on one's liver. It would be wise to do at least some cursory reading on it before taking this advice.
LSD, Ritalin (Daytrana is the best man), Terestrone...
Do you use all of these? And why do you like Daytrana?
Wow, this discussion is mindblowing. Working in software dev for 20 years, in Germany, and I have never seen any developer taking any stimulants. But maybe this is because only my first job was at a young startup, and I quickly learned that working 24/7 just isn't for me and I need a more stable environment.

Today, the way whalesalad and others describe the effect of Adderall sounds interesting to me, but I would never take the risk. I want to see my kids grow up, and I certainly wouldn't give this up just to be able to work more hours...

I feel completely the same! I have been working in electrical engineering in Zurich, and I've never seen or heard anyone use anything other than caffeine during and alcohol after work. Now I wonder whether I'm just naive or there is a massive cultural divide between Silicon Valley and Central Europe w.r.t. stimulants.
Meanwhile cocaine usage in Zürich is one of the highest in Europe ( https://www.swissinfo.ch/eng/drug-capitals_zurich-is-europe-... ) which boggles my mind - I assume this is the finance industry
Not only that but Zurich has been a drug hotspot in the 80s; we had cocaine, heroine, and, we believe, we found out how to fight it: https://www.pri.org/stories/2016-02-12/us-can-learn-lot-zuri...

Now it changed for the better but still the drug scene is relatively big and cocaine is used a lot both by youngsters 18-25 yrs olds and probably also by bankers.

I agree. You really feel how people in Zurich (in social settings) are more tolerant towards drugs than in most other European cities. It's almost like Amsterdam.
I agree. You really feel how people in Zurich (in social settings) are more tolerant towards drugs than in most other European cities. It's almost like Amsterdam.
You really feel how people in Zurich (in social settings) are more tolerant towards drugs than in most other European cities. It's almost like Amsterdam.
I would apply a grain of salt to the claims of people who are avid drug users, as to the popularity of drugs. There is an incredibly strong “birds of a feather flock together,” effect at play. The social circles of people who think they need drugs to do their job are going to only minimally overlap with people who find that notion crazy and dangerous.
So it's two separate cultures at work in the same industry--people who pretty much have no experience or want of drugs and a culture of using drugs, trying lots of things to get a productivity and efficiency boost?
It’s not just in the industry, it’s probably from high school or uni, but yeah you have the idea.
As one of those people, I completely agree. My entire social circle uses drugs in some way. But that means I don't see outside it. And I very often connect with people, adding them to my circle, because we subtly realise we both share that experience. So definitely don't assume my experiences are a random sample of the population :)
> There is an incredibly strong “birds of a feather flock together,” effect at play

Agreed.

As an engineer who doesn't take any stimulants, what does it look like when another person is on Adderall? Maybe I'd notice a person snorting cocaine at work, but if I saw someone taking a pill? I'd figure it's probably just a painkiller, or a multi-vitamin, or for some health condition. Never would I suspect Adderall or some other stimulant. I basically presume that nobody at my office takes Adderall because I would never take it myself.

I can add one anecdatum, I'm from the Netherlands and don't know of drug abuse in the two businesses I interned at. I do know that some friends of mine, who are devs/engineers, occasionally use various drugs recreationally, but never for work.

The only drug use I know of is ritalin or other legal stimulants for those diagnosed with ADD/ADHD, and of course coffee/tea/alcohol.

as someone in his late twenties from the netherlands, i roughly have the same experience. The recreational drug use has more to do with age in my experience then workfields. Most people i know who did softdrugs casually stopped doing so once they either settled down or got kids.

It might just be my enviroment, but alcohol use is rampant and also heavily culturally ingrained in my area. (i live in the southern part of the netherlands. Drinking during dinner is not uncommon for example, even on weekdays.

Same here. I have worked in Germany, Spain and London and never seen any drug use. I would have shocked me for sure. I don't see the point or need.
You need to reply to the comment by Blahah who thinks literally every developer in Germany is high all the time.

I think people who do drugs just gravitate to other people that do drugs.

For me, the limiting factor on my productivity is not how god-like my mental state is, it's whether I can get the info I need from that guy on the other team or when the project manager will sign off on a needed change :)

I live in Germany and can confirm that almost every German acquaintance I have who are in my age(27 have been here since 22) and work in tech has smoked or actively smokes marijuana. According to them it is "no big deal". Both men and women. I worked at an employer in the Cybersecurity industry, many potheads as well, openly so. At that employer there were around 60 people counting the secretaries. I know, for a fact, that at least 10(one woman, a couple of the men with anxiety issues and depression) smoked marijuana, at least one did coke and all had the typical "drink booze till you pass out" German attitude.

Take my anectdata with a grain of salt.

I think in the US people are starting to classify marijuana with alcohol and tobacco. It's not illegal in a lot of states, where I live (in the US) it is legal for recreational use. My understanding was this discussion was about more illicit drug use.
Probably not what you're looking for, but I've cut out anything remotely addicting in my life, including sugar and caffeine. I feel a lot of people in the software industry have the luxury of developing and improving themselves. Most people I work with exercise regularly. Alcohol can be regular in some offices, and people smoke weed, but I don't know anyone who I would consider an addict.
I pass no judgement and just wanted to remind people reading through this that not all techies are doing drugs.
The #1 and #2 drugs consumed by far in Silicon Valley are simply processed/refined sugars and caffeine. The former via foods of all kinds and sodas, snacks, and the later via coffee and sodas.

These are far more dangerous drugs in this sense... even a small child can tell you cocaine is bad for you or that LSD is a “drug”, but no one considers soda and coffee to be drug laced.

These are the real gateway drugs, by far.

If Silicon Valley had decent espresso, no joke, there would be no demand for any of these stupid drugs people are messing with. But the espresso tastes like absolute poop. In the bay area you can market and sell poop drinks as artisinal or small batch or whatever. Its essentially poop. E.g. if you think blue bottle tastes good, I could sell you a cup of poop for $10 easy because you have been fooled.

Back to seriousness, the real problem in all of this is failure to understand the real impacts of seamingly harmless things (processed sugars and caffeine) NOT obviously harmful substances. There must be a progression from the former to the latter. Who the fuck wakes up one morning and says: “shit, works been hard lately, id like to try a line of cocaine, i heard its really great for relaxation”. Wake up, it doesnt happen like that.

Yes, i have conveniently left alcohol out of this ranking, but its #3. If you dont know how bad alcohol is for your brain and body... heh...

The real story is the engineer drinking 8+ cups of black coffee or 10 sodas per day... not the coo ceo or vp doing marijuana or cocaine before work. The latter knows what theyre doing, they may be depressed but they know whats up. The former, probably not. And those seemingly safe substances kick off the dangerous ones.

> The real story is the engineer drinking 8+ cups of black coffee or 10 sodas per day...

Very much agree. Compulsive consumption of sugary/caffeinated beverages is very much an eating disorder. People engage in this at work as a means of coping with stress. There are very harmful side-effects to this behavior: https://www.hsph.harvard.edu/nutritionsource/healthy-drinks/...

I had a bunch of bay area tech friends all become meth addicts while I was out of the country (2001-2008?). It was self-reinforcing. I think a few people on the periphery died, and then eventually it stopped, although I'd drifted away by then. It was just weird seeing people who had used lots of other drugs without becoming addicts become addicts en-masse.
Stimulunts such as speed or ice, are not so good for me, It’s not for creative work also comedown is so hard.

Acid and Molly are best.

I'm a New York-based finance professional (former investment banker turned private equity investor) with a background using a wide variety of drugs, but mostly heroin. Besides heavy drinking and rare cocaine use among younger peers (analysts), I didn't see a lot of substance abuse. I often felt quite alone, especially in using my drugs of choice.

I started using heroin right after I graduated high school, and used it throughout undergrad, as it honestly helped me get better grades by quieting the turmoil in my mind. I experimented with suboxone and methadone after graduation, and was using a mix of methadone, Provigil (a stimulant, to counteract the drowsiness from the methadone), and alprazolam (to take the edge off the Provigil) when I started my first banking job in NY. I was let go for nodding off at work.

At my next job, I started using heroin again after a brief period being drug-free, and started injecting. I had a short-lived job at another investment bank, where I injected heroin, cocaine, or a mix of both pretty much all day at work, even setting up a way to do it at my desk discreetly to avoid having to get up and go to the restroom so often. That job obviously did not last long.

I used like that for a few months, got another job at a bank, and stopped those drugs, but continued to seek prescription painkillers sporadically, and drink to take the edge off. I managed to keep it together for that job, but my overall demeanor made it tough to really succeed. Before starting in private equity, I got sober (no controlled substances or alcohol anymore), and have been sober since mid-2012. It's been the biggest and best decision of my life.

I used to think I was perhaps one of just a handful of finance professionals with as intense background in hard drugs, but I'm coming to see there are too many of us out there.

wow, what an intense journey.
Serious question, how did you obtain a series of banking jobs after previous employers noticed (fired you for?) your drug use? Do prospective employers overlook these things, or never check references?
A lot of times, previous employers won't actually say anything during a reference-check other than to confirm dates of employment.

However asinine, they risk a lawsuit if they say something negative and the candidate doesn't get hired, and there's no benefit to themselves being forthcoming.

Off-topic & realize it's a throwaway account, but would be interested in discussing the career-switch with you.
The only drugs I have observed personally are caffeine, nicotine, refined sugar, and ethanol. The only other drugs I have heard about or suspected are prescription drugs for diagnosed medical conditions, such as hypertension, pre-diabetes, and high cholesterol.

But people around here would tend to keep even the legal drugs out of public knowledge, as that sort of thing may affect background checks and security clearances. Everyone in my workplace is very square. My office-neighbor uses a nicotine vape and prescription mood-stabilizing drugs, and doesn't have a clearance explicitly because of the latter.

It would be nice to be able to get drunk or high a few times a year, but the career risk isn't worth it. I have worked exclusively in the Midwest and South. In general, people of those regions collectively have a rather low opinion of people who use drugs of any kind, legal or illegal, although the Southerners are a bit more hypocritical about it.

Does anyone else want to weigh in about geographical differences in the use of drugs or the perception of those who do? It's very interesting to me how different your experience is from those, say, in the Bay Area or in big coastal cities.
As a Midwesterner, I can echo the sentiment that those who use illegal drugs are generally considered to be lowlifes or otherwise looked down upon by older folks, and some younger ones. Cannabis use is something of an exception - it's seen as acceptable by most of the younger crowd and more of the older folks are being convinced it's not dangerous as well. Legal drugs are a-ok.

For tech specifically, in my experience there seems to be a higher-than-average number of smokers. Coffee and soda are drank as if they were water. That's about it.