Ask HN: Is UK government insane or genius?

524 points by TheAlchemist ↗ HN
While virtually all countries adopt the lockdown strategy to eliminate the virus spread, UK is apparently going on with 'herd immunity' strategy. It's pretty well explained in this tweet: https://twitter.com/iandonald_psych/status/12385183716516495...

Basically, the idea is to get the young infected, as the virus seems to be relatively inoffensive for young people, and thus becoming immune. Once the country reach a threshold percentage of immune population, the virus cannot spread effectively anymore, hence protecting the vulnerable ones.

My gut feeling is that this is the rational thing to do, however only in theory. In practice, people won't be disciplined about isolating vulnerable ones in the first phase, thus leading to disaster.

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This might work. But how many people will die in the process? There are many cases of young people, with seemingly no prior health issues, dying after getting severe issues as a result of the virus.

On top of that, you can't guarantee that young people will only get it. With no travel restrictions, it can easily spread to the elderly.

It kills maybe 1% to 2% of people under 50 with no comorbitities.

If we assume everyone in the UK is under 50 and there are 60m people and we want to infect 60% of them that's 36m people infected, and 1% of that is 360,000 dead.

That's ignoring all the people who do have comorbitieis (diabetes, high blood pressure, etc), and all the people over 50.

It's also ignoring all the people who eg get into road traffic accidents and need an ICU bed, which won't be available if we cram hospitals full of covid-19 patients.

The reported numbers in published papers are more like 0.4% under the age of 50 and 0.2% under 40 and probably lower as there could be a large portion of mild unreported cases.

https://www.worldometers.info/coronavirus/coronavirus-age-se...

>> Death Rate = (number of deaths / number of cases) = probability of dying if infected by the virus (%)

That's not a great way of measuring the death rate during an on-going epidemic. They should be measuring the number of people who died today / number of cases a week ago.

Why a week ago? If it takes longer than a week for victims to die, in a situation with rapidly increasing infections that will give a very distorted number.
The best source I found on the subject -- a disease modeler with CDC who was giving an interview -- said that their current estimates used 5-day doubling, 15-day median time to death, and 1% CFR to do their estimates.

For the modeler, the purpose was estimating the true number of cases (which they estimate as current_deaths * 800 for a first-order approximation) -- but similarly, you could use that to estimate CFR by taking (num_cases / 8) as the denominator. Except, of course, that you can't realistically estimate num_cases. With the exception of Diamond Princess and possibly South Korea, everybody's numbers tell you more about the number of tests they run than the number of infected that exist.

One doctor from John Hopkins, for example, estimated that there are between 50k and 500k cases in the US as of 3 days ago -- and my own admittedly-amateur estimations using CDC numbers for deaths from influenza and all-cause pneumonia could only set an upper bound of ~400k cases as of March 1st

Sure, maybe just one week is too short and it needs to be longer. But that just makes my point stronger, doesn't it?

Using the total number of people infected today means they're including a bunch of people who may go on to die, but they're not including those deaths yet. So they're making the death rate look smaller than it is.

unless the world plans to stay isolated until there is a cure this may be the alternative that doesnt also bankrupt a lot of businesses and put people out of work.
There will be pockets that will see this carry on for years globally. Currently it is mostly prevalent in climates in their winter phase months, and UK just entered spring.

Then there is this virus mutating, could it mutate into something less harmful, or something more harmful.

Past pandemic the spanish flu saw the initial infection decline in the summer and in the winter saw a higher wave of infections and deaths - which would be at a time when health services with climate phases tend to be less able to handle extra volume.

Policy seems to be around accepting people will die, no escaping that or dressing that up and to manage infected and control the spread and managing response/restrictions accordingly. So by managing the effected numbers needing medical intervention and dragging out the first seasonal phase so that the summer months lul can be used to level out the impact down the line.

It is very much more likely that, as it mutates, it will be to a less-deadly virus.

Evolutionary pressure works that way -- as a less-deadly version will spread faster and outcompete a more-deadly version (because it won't kill as many hosts -- dead hosts cease spreading -- and because less-ill hosts are less likely to stay in bed until better, thus encountering more people and thus more spread)

This is why, broadly, endemic diseases like influenza become less lethal over time

It's why severe influenzas are usually those that just mutated to cross over to humans from some other animal -- like swine flu from last decade, which was not that deadly to swine, but remarkably so to humans those first seasons, or avian flus which also have appeared occasionally.

The Spanish Flu was one of those -- an Avian flu that had newly mutated to infect humans.

Spanish Flu mutated into a far deadlier version over time because it spread faster in hospitals and troop transports than on the streets. We may see a similar situation with corona virus if the quarantines and social distancing are too effective. Ideally, we want most cases to be transmitted from the weak cold-like corona virus cases, not the lung-infesting killer cases.

https://en.wikipedia.org/wiki/Spanish_flu#Deadly_second_wave

To quote that article:

In civilian life, natural selection favors a mild strain. Those who get very ill stay home, and those mildly ill continue with their lives, preferentially spreading the mild strain. In the trenches, natural selection was reversed. Soldiers with a mild strain stayed where they were, while the severely ill were sent on crowded trains to crowded field hospitals, spreading the deadlier virus.

Given that, the UK policy seems to make more sense now, thank you.
The problem is that nobody knows whether this virus will behave like that. Flu does, as did SARS. But MERS has no issues with killing people in Saudi Arabia in 50 degrees Celsius.

That this virus is prevalent during winter time is simply a coincidence - it has started in November and most countries affected happen to be in the northern hemisphere where we are coming into spring only now. However, there are documented cases in Australia and New Zealand too - which have late summer now.

Once testing procedures are prevalent, and the curve has been bent, there is no reason why you cannot continue largely as usual well before a cure or vaccine exists.
and causing the deaths of >80 year olds, thus reducing the costs of dependency on the health system? #consipracy :)
However this age group is also predominantly conservative voting so they would not want to off their core support base.
On the other hand the next election is nearly five years away, by then most of them will have fallen off their perch anyway.
This in a nutshell. The tory party hate spongers.
There are already some reports of re-infection. It may be that immunity isn't so easy to build for this virus. Not enough is known about it yet. This is a huge gamble.
What reputable officials are on record regarding re-infection, please?
I don't think there is any evidence of reinfection. What seems to have happened in some cases is that a person's symptoms have dissipated but resurfaced a bit later. In other words, the patient thought they had recovered when they hadn't.

That said, the chief scientific officer has stated that this is likely to be an annual virus: https://www.telegraph.co.uk/news/2020/03/13/coronavirus-outb...

I had the same discussion a few days ago and someone posted https://www.businessinsider.com/wuhan-coronavirus-risk-of-re... [It has a link to a video, but the caption of the video is wrong. The recommendation to the cured patients is not to increasing their physical activity but to enhance their own health safeguards.]

I found two other articles about the same case https://globalnews.ca/news/6623287/coronavirus-multiple-infe... and https://www.reuters.com/article/us-china-health-japan/japane... . t's not 100% clear, but it looks like a continuation of the first infection after a few week of no symptoms. It makes more sense than no immunity (at least at the short time), and a second independent infection.

There are a few suspicious cases but given how human immunity system works, it is very very unlikely that it is due to reinfection (i.e. a cured patient getting infected again).

A far more likely explanation is either poor testing that gave a false "all clear" while the patient was still sick. The tests are not 100%, that you don't detect the virus in the sample doesn't mean that the patient is not infected - it only means your sample didn't contain the virus. Which could happen for all sorts of reasons. That's why multiple tests are usually required - commonly two, in some cases up to eight consecutive tests had to be clean before the patient was discharged.

Or the patient has not been completely treated and the virus became dormant for a while, reappearing again later. This is known to happen with other diseases as well - e.g. ebola virus could stay dormant for weeks in the eyes and cause the disease to return again.

Important to remember that this person doesn't know what the policy is. They're just tweeting their opinion.
The UK government announced the policy in a press conference with the Prime Minister and the chief scientific advisor.

Here is an interesting follow up interview with the chief scientific advisor: https://www.youtube.com/watch?v=2XRc389TvG8

My personal opinion, after watching the interview, is that the UK government is not doing anything that radical. They will follow the reactions of other countries but want to time the reaction so that it is most effective.

They didn't word it like the OP. The OP got that from the Twitter account extrapolating the contents of the press conference. The press conference mentions herd immunity but it didn't (like the twitter thread) state that keeping schools open was to ensure young people get infected.
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So let's assume that building immunity is even a possibility even though there is no evidence to support this while there exists substantial evidence to the contrary (people getting reinfected)?

Not happy to be living in the UK if that's really the plan.

> while there exists substantial evidence to the contrary (people getting reinfected)?

No. There are instances of people testing negative and then testing positive again, but the strong consensus is that this probably results from faulty testing and/or changes in how viral material manifests at different stages in a person's infection. The chance is very small that people are truly getting re-infected.

>No. There are instances of people testing negative and then testing positive again, but the strong consensus is that this probably results from faulty testing and/or changes in how viral material manifests at different stages in a person's infection. The chance is very small that people are truly getting re-infected.

This is also why testing everyone and anyone is a bad idea. Half or more of positive tests of people without symptoms being tested because they are in close contact with infected seem to be false positives. https://www.ncbi.nlm.nih.gov/pubmed/32133832 I've seen something else I can't find at the moment that says that only about 10% of those with both potential COVID19 symptoms and a contact history indicative of possible contact are positive. It's both pointless and dangerous to have someone get a false positive reading, perhaps do self-quarantine for 14 days, then go out and promptly get (not re)infected.

The US government (and I think UK too) is getting a lot of criticism for restricting testing to those who meet the requirements of symptoms and contact history, but it's almost certainly because the CDC is aware of this. The Canadian government, too; Prime Minister Trudeau is not being tested, although his wife is positive, because he is asymptomatic. https://www.usatoday.com/story/news/world/2020/03/12/sophie-...

https://twitter.com/AdamJKucharski/status/123882151552689766... appears to give a better explanation from the modellers.

The aim is to flatten the curve, any herd immunity is a by-product but not the aim.

I think herd immunity is an integral part of the strategy. If a population never gets herd immunity, it will keep on getting infection breakouts and keep on having to impose lockdowns. The only way to stop doing lockdowns is either to prevent the ingress of the virus, ever, or eventually reach herd immunity.

The virus is everywhere now, it’s part of the landscape, so preventing breakouts is just flat out not possible, at least for large countries with lots of travel and especially with large rural hinterlands like the UK. In this view the only strategies are long term strategies.

There is a way to get herd immunity without an epidemic, and that’s inoculations. However we do not have a vaccine yet and have no idea if or when we might ever get one. So you can bet everything on red 13 and cross your fingers for a vaccine in 6 months, or pick which longer term strategy works best for your country, with its particular demographics and geography.

> However we do not have a vaccine yet and have no idea if or when we might ever get one.

https://www.jpost.com/HEALTH-SCIENCE/Israeli-scientists-In-t...

If I had a dollar for every COVID-19 vaccine that will be ready "soon", I'd have quite a few dollars.
> so preventing breakouts is just flat out not possible

Why not?

Because it isn’t possible to screen every single person entering a country like the UK, which means it is inevitable the virus will get in again and you’ll have another outbreak.

However that’s assuming you can eradicate it. That might be possible in an isolated population centre like Singapore, but the UK has an extensive rural area where the virus can hide out, slowly propagating through many different sparse populations until it gets back into an urban centre. It can survive outside the body on some surfaces for 9 days according to recent studies so it can infect someone who has light symptoms, they put it on a new surface, then when they recover up to 9 days later it can up again in someone else. This can go on for months. You might track down some of these smouldering brush fires, but not all. That’s how flu keeps coming back every winter.

> Because it isn’t possible to screen every single person entering a country like the UK

Why not? Personally, if I were put before the choice of not having more people enter my country than I can screen or killing off 1M+ of my electorate, I'd at least seriously consider the first option. Meanwhile the UK government clearly thought that even stopping the flow of people from an epi-center, fleeing quarantine (or at least tracking them) would be a grave over-reaction.

> You might track down some of these smouldering brush fires, but not all

I don't see why you can't keep it reasonably contained even with occasional flare ups. I'm not saying you are wrong, but it is certainly not self evident. Since the Chinese were willing to kiss good bye to something in the vicinity of $1T, presumably they think they can. If you keep perfecting testing and procedures and hold out till you've got a vaccine, I don't see that would not be a winning strategy.

> That’s how flu keeps coming back every winter.

Well, this is way worse than the flu and may get worse still, so we should be very motivated to kill it whilst we can. Also, looks like there'll be more where this one came from. Just taking a big hit to global life expectancy every few years will probably start to add up over the long run.

>> Because it isn’t possible to screen every single person entering a country like the UK

>Why not?

In addition to major airports we also have many minor ones and private airfields. There are 120 commercial ports, and many, many more smaller docks, quays and marinas. We have many islands and remote coastal communities that rely on these for essential supplies and no systematic way to monitor them all. Even then, sealing ourselves completely would have to include stopping goods because goods are carried by people.

Also we now know the virus can survive on cardboard for up to 9 days. We don't have 9 days worth of supplies of everything in the country and don'y have a tracking system for every shipment in or out. We know from the Brexit analysis that we can't track goods enough to tax them, so clearly we can't do the same for medical reasons.

Finally, even if such a lockdown were practically feasible and we developed the logistical and administrative capacity to do it overnight, which we can't, it would destroy our economy. That would inflict massive hardship, particularly on the old and vulnerable, exactly the people we most need to protect. Hardship and poverty kills people, and shutting down all trade and commerce until we have a vaccine, which could be several years or even indefinitely, would take us back to the stone age. It would be far, far worse even than during World War 2, and that's how severe it would have to be to prevent the virus getting in, not just for months but probably for one or more years.

Anyway thats a fantasy, we just don't have the logistical or administrative apparatus to do it fast enough for it to matter.

The government isn't going with a herd immunity strategy. It's waiting for the most impactful time to lockdown.
The primary reason why other countries go into a lockdown is to prevent their strained healthcare systems from collapsing.

It's not just sick people who can't get a hospital bed. It's everyone else too. People who get heart attacks, strokes, accidents, other illnesses,...

A lock down is NOT meant to stop the virus in its tracks. It's meant to slow the infection rate and avoid hospitals and health care centers from getting swamped.

Any chart about China and Italy published thus far shows how the infection rate thus far grows exponentially. As such, the most impactful time to perform a lock down isn't next week or in 10 days. It is NOW.

The "herd immunity" strategy isn't a strategy. By the time this is over, the population will have achieved "herd immunity" regardless of how this will have played out. What matters is where we would like society to end up 6 months down the line: a relatively preserved, functional society with low mortality; or a dysfunctional one where likely anyone of this forum will have lost loved ones.

This is not updated for March, but here's a chart that disagrees. China's new cases started dropping after the lockdown: https://miro.medium.com/max/9350/1*r-ddYhoUtP_se6x-NOEinA.pn...

From https://medium.com/@tomaspueyo/coronavirus-act-today-or-peop...

That was also around the time that -- according to credible sources -- doctors in China were given a quota of cases that they were allowed to report each day.

I guess we'll see what happens with other countries, and then that can give us a sense of how many patients went unreported in China. Perhaps it was a lot, perhaps it was only a few.

I think the core message of Tomas Pueyo's blog post is sound, but he undermines it completely with the number juggling.

He's not a specialist. He's not an expert. This is an entrepreneur who knows how to create viral content. His previous blogpost was "How to deliver a funny speech".

So, I wouldn't accept the details, the number or the graphs he has cobbled together at face value. This is true for pretty much anything that is published on medium.com and doesn't come from a sources verified by experts or officials.

While people are slightly optimistic about China and South-Korea, I think it's far too soon to try and make any detailed forecasts on how the next few weeks will pan out. We simply don't know enough yet. All we know is that this is an infectious disease spreading at a lightning speed. Stay home, and adhere to WHO and health administration protocols. That's all there is to do right now. Anything else is conjecture until this has played out completely in a few weeks time.

I wonder how much of it is just playing the odds. Shutting everything down will very likely have a large, but fixed consequence on the economy, which has huge cost, including in lives and health. Whereas biding your time increases the relatively small risk of catastrophic consequences from coronavirus, but avoids the economic consequences. So it comes down to a choice between accepting a known downside, or taking a gamble on a path with the possibility of very little downside, but also much larger worst-case downside. Leaving the expected values of the choices aside, maybe Boris just likes to roll the dice?

There are other considerations, like how well the president/prime minister’s incentives are aligned with the countries. Donald Trump, through very little fault of his own[1], faces the possibility of a failed presidency due to the economic consequences of shutdown. If possible, a president might think it worth swinging for the fences, if he is down a couple of runs in the ninth? If he strikes out, he is no worse than before, although the country is. And Boris has kinda made himself out to be a guy who tries for home runs, at least in his public persona.

There is also the game theoretic considerations on the country level. If all the other countries are doing everything to stop the spread and paying the economic cost, than U.K. can take the benefit of that sacrifice, and not crash it’s own economy.

[1] of course he is doing his best to compound the external factors.

All of this ignores the moral aspect of sacrificing human lives at the feet of the economy. And, to be fair, it's totally plausible that said leaders are themselves ignoring the moral aspect. But it does matter when we judge them on the actions they decided to take (or not take).
> through very little fault of his own

https://www.snopes.com/fact-check/trump-fire-pandemic-team/

Get out of here with this. We had expert teams and processes in place to combat the possibility of this exact thing and his administration fired them without any replacement.

The virus existing is not his fault, but nearly all of the national consequences rest directly at his feet.

I worded it that way because I think that even if he had done everything right, his re-election would still be in trouble because of factors outside of his control.
The job is literally to be prepared for the future on behalf of the country. If you take active steps that make us less prepared for something and we therefore suffer greater consequences when it happens, I have a really hard time describing that as being something outside of your control.

Under normal circumstances, an exigent crisis such as war would make a President significantly more likely to be re-elected. He tried to start a war with Iran not long ago for this very reason.

If you want to argue about Trump, please find someone else to do it with (or somewhere else to do it).

My comment was not about Trump's response, and I regret even including mention of him, since that one offhand comment has generated uninteresting political arguments, without anybody engaging with what I was actually writing about.

Snopes stopped being a reliable source a long time ago, if they ever were. They give one-sided versions for obviously political reasons.
>Get out of here with this. We had expert teams and processes in place to combat the possibility of this exact thing and his administration fired them without any replacement.

Ah yes, yet another person who looked at the Snopes piece's headline and nothing else. One would think reading only that, or the Twitter thread (!) the piece is based on, that to save money (or because the Trump administration hates science, or something) the entire "US Pandemic Response Team" agency was eliminated and everyone in a large DC office building was fired.

Actually reading the contemporary NBC News https://www.nbcnews.com/politics/politics-news/tom-bossert-t... and Washington Post https://www.washingtonpost.com/news/to-your-health/wp/2018/0... articles the Snopes piece cites in the body, they seem to have been a handful of people in one team in the National Security Council hierarchy, that the new National Security Advisor reassigned to related agencies, as part of a desire to have his own hierarchical structure. Ziemer resigned because he wanted to keep his team the way it was.

COVID19 was not a surprise; that is, it was known to exist in China some time before the first cases appeared in the US. It is not unreasonable for a government to assemble a team to respond to something like a pandemic as needed, as opposed to having people dedicated solely to the purpose and nothing else. And that's exactly what the US did, implementing the ban on non-American travelers who'd been to China in late January, among other things.

You may or may not agree with this. But please don't claim that this is somehow prima facie proof of the Trump administration's malfeasance/evilness.

PS - No, Trump did not "cut the CDC budget" either. https://apnews.com/d36d6c4de29f4d04beda3db00cb46104

No, Trump did not "cut the CDC budget" either.

No, he only proposed cutting the CDC budget. Luckily, saner minds prevailed.

>No, he only proposed cutting the CDC budget. Luckily, saner minds prevailed.

Presidents do not pass the budget; Congress does, under the Constitution. The annual President-proposed budget is just that, a starting point from which to negotiate from. Both the House (currently controlled by Democrats) and Senate (Republicans) have to pass it.

If you criticize the president for starting out with a proposal for cutting the CDC budget (and for most other agencies), why not also praise him for signing the final budget that raised its budget?

I don’t find anything praiseworthy in his actions re this crisis, he has and will continue to handle it really badly IMO.
From a PR point of view this is not a clever move. The very phrase 'herd immunity' says a lot about what they think of people. It is also a highly memorable phrase, much like 'shock and awe' and sometimes you just don't need a 'marketing slogan' for something divisive.
It's a technical term.
> The very phrase 'herd immunity' says a lot about what they think of people

...You know they didn't invent the phrase, right? It's a term of art, and has been the standard term for that epidemiological concept for many decades. https://en.wikipedia.org/wiki/Herd_immunity

I did not claim that they invented the words. English is a rich language and some words resonate better. From your article:

> Herd immunity (also called herd effect, community immunity, population immunity, or social immunity).

Community immunity would rhyme and not be received as negatively by those that already hate the government as the herd word. It would also convey community, which is a caring nice word.

I'm pretty confident they'll start copying everyone else in 10-14 days.

They are ignoring any sensible model of this and they won't be able to deal with the uproar once the numbers reach a psychological threshold. Happened last Sunday in Spain BTW.

> They are ignoring any sensible model of this

Meaning what? They've explained their reasoning.

That's an aspiration more than a reasoning IMO. Meanwhile that R0=2.28 is doing its thing and it can't be good for the NHS, meaning many ugly pictures. The thing is when tabloids are going to get hysterical about this.
Doing what someone else does, but a week later doesn't necesarily mean you made a mistake, or that you are a week late in making a decision.
I think it does, you don't wait a week to put out a fire, it gets worse. China has essentially contained it already. Maybe alternating lockdowns and releases we might be able to keep it manageable until there's a vaccine.

This is not hard to model once there are a few cases in a population, again IMO.

> you don't wait a week to put out a fire, it gets worse

I don't think putting out a fire has any major adverse effects, so perhaps not the best comparison.

There's always side effects to everything you do, but if we're being picky about the fire analogy (maybe I'd rather go to the beach than putting out a fire right now), I'd agree I should have used a gangrene one.
How much does every day in lockdown hurt the economy?

Flattening out the infection curve too much means increasing the economic harm by a much larger degree.

Calling a lockdown a week too early, means continuing it a week extra on the other end or you risk a sudden, unmanageable peak.

I don't envy any politician the decision, but pandering to panic and locking down too soon will cause a lot of harm too.

At a larger level, "hurting the economy" may be the best thing to happen in a long time for (1) the environment, e.g. clean air, (2) family time, (3) cutting out some useless activities that go on due to sheer inertia, like formula-1, olympics, auto shows, most conventions, etc., (4) give people and societies a chance to slow down, think through things and refactor a system that was running full speed towards the wall anyway.
Doesn't seem so clear. During a recession, you might have less money for investing green technologies. No one will be able to afford an electric car. You might get more family time but the stress of the main earner being unemployed will mean it's not high quality.
I really wonder why we can't all just slow down the money circulation. There are many business and people endangered by the situation? They can't earn enough money? Well they don't have to pay the full price for basic needs, mortgages etc. People living on this stop gaining money like before? Discounts for them as well, they just keep working for the greater good because we are in a unique situation. Rinse and repeat until we go full circle.

What's the problem here?

The (totally made up number) 15-20% of greedy people who put money first no matter what.

It's really sad.

> No one will be able to afford an electric car.

I realize my opinion may not be the mainstream one, but I think the 2008 financial crisis did more good for the environment than all the "green investments" of the past few decades.

> the stress of the main earner being unemployed

That can indeed be a problem for families. I hope the crisis will bring about some reduction in consumption/travel, downshifting, rethinking of priorities, simpler living.

I'm somewhat puzzled about this doomed economy idea. Many businesses are doomed of course, but some opportunities arise: economy changes, it adapts to the environment. We've been building the perfect tool for this scenario during the last 25 years, if we manage to sustain the logistics the economy won't stop. Had this happened in the early 90s we'd have been in deep trouble.
Reduced spending on leisure, tourism, travel, etc, less decisions made because no meetings, etc., will MASSIVELY outweigh any opportunities.

Even putting aside the sick leave, which will happen either way.

If they do indeed go into lockdown it’s almost certainly a massive mistake.
I am not knowledgeable enough to endorse/criticise the plan. But watching the various statements yesterday by the government/scientists it's clear that they do plan for lockdown, just not yet. But it's fully expected in the coming weeks.
It certainly does if your inaction causes lives to be lost. A week or two here can be thousands of more deaths
Yes, they've already said that they will bring in those measures in a week or two.
I’m going to try and lay out the case in as neutral terms as I can, although to be clear I think they are probably right. They’re going to take an awful lot of stick for it though, and indeed already are.

They believe that there are basically two mitigation strategies. One is to have a very drastic early lockdown that shuts down the virus before it spreads widely. The problem with that is, once you lift the lockdown it will simply start all over again. The problem with this is lockdowns are most effective the first time you do them, and then mostly in the first few weeks of the lockdown. Do it too early, and yes it will be very effective in the short term, but later on when cases become much more prevalent the lockdowns will be less effective.

The option they are going for is to start the lockdown a little later in the cycle. The hope is this will make the lockdown more effective at a higher point in the spread. Effectively instead of a series of booms and busts, you get one longer slower initial burn and then you’re mostly done. They believe that in the long term this will make it easier to protect those most vulnerable to the virus, because you only have to do it once, at the cost of increased prevalence among people least vulnerable to it. So they see it as a better longer term strategy.

But there's a third strategy that works better than either: don't lockdown, but do effective testing, case tracking, and treatment, well enough so that exponential growth can't happen in the first place. That's the policy of Hong Kong, Taiwan, and Singapore, who are doing great.
That’s a very good point, you’re quite right. However all three of those are relatively very small population centres with very easily controlled borders. Britain does have the advantage of being an island, but it has a large rural hinterland that the virus can ‘hide out’ in, and many dense population centres without borders, so it’s a completely different environment.

Take London. We could introduce a system of tracking and isolation within the M25, and that might work to lock down community transmission within the London population, but millions of people flow into and out of London each week so it would be completely pointless and ineffective. Meanwhile that level of tracking and isolation simply can’t work across the whole British isles. It’s administratively and logistically impractical.

> millions of people flow into and out of London each week so it would be completely pointless and ineffective

Was curious about this point in particular - checked the numbers, and Heathrow has essentially equivalent traffic as Hong Kong International.

There are 5 other international airports that call themselves "London", not just Heathrow. And of course London also has road and train connections.
I was mainly thinking about road and rail traffic into and out of the city, including daily commuters.
The equivalent of the entire population of Glasgow passes through Kings Cross station in the morning rush hour. There are 4 other stations with similar flows. Over 20 million people live within an hour or 30 miles of Piccadilly Circus.
That level of population flow and population density are not as special as you are making them out to be. The transfer station nearest Seoul's most recent cluster (discovered 7 days ago) gets about 25% more annual traffic than King's Cross, according to Wikipedia (125,000 per day at Sindorim Station vs. 34 million at King's Cross annually). Despite the cluster having developed at the beginning of March, Seoul is finding fewer than 100 new patients per day. With masks, reduction in ridership, cancellation of meetings, extensive WFH, extensive testing and isolation measures, this epidemic is not as hopeless as the UK seems to be making it out to be.
I completely agree. I was shocked to hear that only people that present with symptoms that require hospital treatment are now being tested.
That's the policy of Hong Kong, Taiwan, and Singapore, who are doing great.

All of which have tiny populations compared to the UK.

For larger nations, there simply aren't enough tests available, nor enough treatment facilities for those who are likely to become very sick if the virus spreads rapidly through the population.

> For larger nations, there simply aren't enough tests available

Why? If your nation is twice as big, then all else equal, your government has twice as much money, twice as many resources, and hence twice as many tests. China now has more tests than they need and they're the 2nd most populous nation in the world.

No amount of money helps if there aren't enough tests available to buy. What is missing are manufacturing and distribution facilities, which of course are calibrated to the normal levels of work and not to a relatively sudden pandemic outbreak of one particular virus.

China has huge resources but has managed so far to keep the infection mostly contained to one specific area. It's not clear how long they'll be able to sustain that or whether they'd have enough resources to go around if all of China were the same as Hubei.

Of course all of this also assumes that tests are effective and that you can then do something useful if you confirm that a patient is indeed infected.

> All of which have tiny populations compared to the UK.

Is 66 million really that qualitatively different than 24 million?

The honest answer is that I don't know. Perhaps I generalised too readily before, given Taiwan is quite a bit closer to the UK in population than the other two.

Even so, assuming that strategies that appear to have been relatively successful in a smaller, more densely populated country will necessarily also work in a larger and less densely populated one seems to be dubious. We know that we don't have the resources we'd need to implement that strategy in the UK right now, and I haven't personally seen any experts arguing that it's a viable option for us, so I'm cautious about extrapolating too much here.

China doesn't have a small population and has it under control. I don't think it's a population size thing.
China does seem to be on of the most interesting cases so far.

The quarantine measures, once introduced, do seem to have been viewed favourably by the experts and do seem to have been remarkably effective. This assumes we trust the reported statistics, which I acknowledge as a possible risk in this instance.

On the other hand, it may be that China has been able to achieve that in part by pulling resources from all over to focus on the main region affected. That isn't necessarily an option that will be open to other nations, particularly if their outbreaks are distributed across their whole area almost immediately.

Taiwan population is smaller, but not really "tiny" compared to UK's.
and much denser populations, with a lot of international travel. which have a huge culture of eating food in hawker centres which would really seem to make a big threat to containment yet they appear to be doing well.
Taiwan is 23 million people. The UK is 67 million people. The level of confidence of your comment does not seem to be warranted by your level of knowledge.
Please don't make comments like this on HN. They lower the tone and add nothing of value to the discussion.

We have explored a little whether the population of Taiwan being somewhat closer to the UK's than the other two named countries was significant in a sibling thread.

In addition, in the UK, which is the subject of this discussion, it is certainly the case that we do not currently have sufficient resources to cope with a widespread, uncontrolled outbreak. There have been a number of further announcements today regarding how the government is hoping to acquire new space for treatments, acquire essential equipment like ventilators on a much larger scale than is currently available, and bring in more trained staff to make use of these resources to help treat coronavirus patients. Even if these plans work out as is hoped, all of them will require at least several weeks to make a large difference. This isn't my opinion, it's coming straight from senior government figures and their senior medical and scientific advisors.

I'd like to ask you to not make comments like the one you did — confident assertions about things you know nothing about, that you haven't made even the most trivial effort to verify, whether that's the population of Taiwan or the general relationship between country size and testing kits per capita. Regardless of how politely you make them, statements unconnected to any concern for truthfulness lower the signal to noise ratio, and they add nothing of value to the discussion. On the contrary, calling out such recklessly false statements does add something of value to the discussion.

Instead of criticizing my tone, which was in fact fairly restrained, you should thank me for taking the time to correct you. For instance: https://news.ycombinator.com/item?id=22580049 https://news.ycombinator.com/item?id=22569806 https://news.ycombinator.com/item?id=22529609 https://news.ycombinator.com/item?id=22505631 https://news.ycombinator.com/item?id=22504690 https://news.ycombinator.com/item?id=22370446

It is true that the UK does not have sufficient resources to cope with a widespread, uncontrolled outbreak, lacking for example one to two orders of magnitude in ventilator capacity; but, as should be obvious, this is not a result of the UK being a large country — the UK is much smaller than China, slightly smaller than Japan, the same size as South Korea, and slightly larger than Taiwan. But this conversation would be of higher quality if, instead of containing such your obviously false assertion and also fact-based rebuttals such as these, you had not posted the assertion in the first place (perhaps because you had read enough to see that it was false), so no rebuttal would be necessary.

Continuing to adopt such a hostile tone still doesn't further the discussion. I am happy to debate this subject, but I will not reply further if you continue to make unnecessary personal attacks in your comments.

Is it your contention that the countries you mentioned do have sufficient tests and treatment facilities available to successfully implement the "third strategy" advocated by knzhou in the comment I first replied to? I can see little evidence that would support such a claim so far, in this discussion or otherwise.

China's recent official statistics may not be entirely trustworthy: they showed the expected exponential growth curve earlier on, but then levelled off remarkably quickly. In any case, its strategy has so far been primarily one of containment, with resources focussed on one specific area, Hubei, where the outbreak was also concentrated at the start. It is not known whether China has an effective testing or tracking regime in operation at this point, nor whether it has sufficient resources to treat large numbers of people if they became seriously ill in the absence of that containment, as may yet happen when the heavy quarantine measures are eventually lifted.

Japan's official statistics have also attracted scepticism, with the suspicion that they aren't testing widely enough to get an accurate picture of how the virus is spreading.

South Korea has had possibly the most successful response so far in terms of credible raw numbers and as such it is certainly worth looking at, but the strategy there has also been primarily one of containment. Again, that doesn't tell us anything about whether SK has the resources to look after much higher volumes of intensive care patients than usual if those containment efforts fail, or if heavy lockdown measures were not attempted and instead that "third strategy" of test, track and treat were used.

The UK isn't just "slightly larger" than Taiwan, it has almost 3x the population and almost 7x the land area. As I already acknowledged in the other thread long before you replied to me, I may have chosen too strong a word when I described three countries including Taiwan as having populations that were tiny compared to the UK, but my fundamental point stands in that we should not assume a strategy that could work at the scale of Taiwan would necessarily also work at the scale of the UK.

You argue for fact-based rebuttals, but where is the evidence that your examples are countries that do have sufficient testing and treatment facilities available to employ that test, track and treat strategy rather than the stronger quarantine measures that most countries are attempting?

There are quite a few difference.

HK, Taiwan and Singapore all acted extremely early on, to the point where HK knew before the news broke out in China. And the culture allows you to wear mask, which seems to be something most western nation are completely against.

Most part of Europe and UK reacted very late in the cycle. Since the Virus has an extremely long stable period before any symptoms appeared or to the point where you could be infected but showing no symptoms at all. It highly likely they are already in wide spread. 500 people each inflecting two, do that 11 times and we have 1 million infected.

Then there is the death rate, at least so far it seems to be extremely mild for anyone below 50.

Not saying I totally agree with Herd Immunity, but judging from the current data and situation it is possibly the best route to go.

Isn’t that the whole point of a lockdown? After ~6-8 weeks you get the new infection rates down low enough that you basically reset the clock and have a second chance at responding like Hong Kong and keeping it in the containment phase. Then you have to keep that up for hopefully 9 months until a vaccine is available.

It’s certainly not easy, but it seems possible and it’s not clear this would be much worse on the economy in the long run. Plus it saves half a million lives, so it seems like a moral imperative to at least try.

>Isn’t that the whole point of a lockdown?

You will need a Lockdown AND Mask, or you will simply just need Mask and not even lockdown. I would argue social distancing only is not enough. But somehow even people in Italy refuse to wear mask. So I think a culture issue is also a problem there.

I don’t think masks are as effective as you think. WHO says only wear a mask:

If you are healthy, you only need to wear a mask if you are taking care of a person with suspected 2019-nCoV infection. Wear a mask if you are coughing or sneezing. Masks are effective only when used in combination with frequent hand-cleaning with alcohol-based hand rub or soap and water. If you wear a mask, then you must know how to use it and dispose of it properly.

https://www.who.int/emergencies/diseases/novel-coronavirus-2...

Except we have clear evidence with all the countries listed above, SK, HK, Singapore, Taiwan that wearing a mask is effective. Even in many cases without social distancing. There are little working from Home in majority of the business in those cities, They have a much higher population density that has a higher chance of being infected with coronavirus.

The mask also protects you from bad actors who are not doing any standard hygiene procedures such as washing your hands.

We don't have enough masks in Europe, and those few are needed for professionals.

Besides that, I think that especially in times like this, it is important to stick to the recommendations of experts. Here in Germany, the expert recommendation is akin to the parent comment. These recommendations are crafted by people with a lot of expertise on the subject and who care for the health of people, and I think it is not productive to fundamentally questions their advice.

>We don't have enough masks in Europe, and those few are needed for professionals.

That is the only valid argument I could possibly understand. Although I would argue we could have ramp up production line. And Medicals get priority with Mask.

>I think it is not productive to fundamentally questions their advice.

I dont know, but Japan, South Korea, Taiwan, Hong Kong, ( We exclude China for comparison ) 200M+ Population together has far fewer death than just Italy with a population of 60M. Let alone Europe. And people are dying.

But hey, I guess as long as the people in Germany and Italy and UK are happy with what is being done then that is fine.

It's not only this reason. Even N95 masks are rated only to .3 micron. COVID-19 is .1 micron. It will prevent droplets from those already infected but I don't see how it would help in the healthy much. Maybe it slows down the air breathing out? But I don't see that helping a lot.
Arh. I see it now. When ever Mask is mentioned in the context of CJK, it meant medical mask with 95% PFE, VFE and BVE mask. Stopping size of 0.1 Micron.

Sorry I wasn't being clear enough. We knew very early on N95 doesn't work.

> It’s certainly not easy, but it seems possible

If your population already has lived through similar outbreaks, sure.

But look at the US. There is a sizable portion of the population who thinks this thing is a hoax, who simply don't believe in this pandemic. How do you lock down those people? They're going to completely ignore government recommendations, and they'll scream bloody murder when government cancels events and restricts travel and assembly.

But let's say you manage to lock down the US to contain the current wave, and that you manage to ramp up testing so that you can be more sure about actual infection rates. Once it dies down in the US, then what? Ease the lock down? What about other countries where it's still rampant? What if it flares up again in the US? Go into a second lock down? You've already spent an enormous amount of political capital getting the first one through, good luck getting a second one.

> Plus it saves half a million lives

You pulled this number right out of your ass by multiplying a guesstimated death rate as measured in China, where the virus spread unchecked through an entire province, and where the medical system wasn't prepared, and you're assuming that the demographics of the people catching the virus in the UK is going to be the same.

But if your medical system is prepared, if you're quarantining vulnerable people, if you have good testing, then letting the virus roll thorough the remaining un-quarantined population won't lead to the same death rates, or the same hospitalization rates, because all the underlying factors are different.

It's far too early to say whether they're doing great. Several months too early. Their lockdowns are preventing virus spread now, but at some point, the lockdowns will end, and then there is a vulnerable population waiting to be infected by a carrier coming from abroad. Will they be able to keep carriers out? Will they be able to respond to further outbreaks with more lockdowns indefinitely? Will there be a vaccine soon enough that they can protect everyone and then end the lockdowns before it all goes wrong?

I don't know enough to say that the UK strategy is correct (i hope it is - i live here, and more importantly, so do my parents). But i think the situation isn't cut and dried.

Hopefully, we will get a lot more detail in the next few days, and then the real experts can come to a consensus.

I would rather have the spread stopped/slowed domestically with aggressive measures than to do little to nothing to stop the spread thinking it will somehow solve the problem.

The UK approach here is basically just accepting that a majority of the population is going to get infected by design. That's fine. It might even be true. (It obviously will be if you don't do anything to stop it, but even in aggressive lockdowns I mean)

But it benefits nobody to have it spread quicker. Maybe life in the UK gets back to normal a little faster for people who are not at-risk or aren't treated at risk but we live in a very global society and if everyone else is locked down then it's hard to see much benefit for the UK itself.

And your parents and the portion of the population who are most vulnerable are more at risk.

An imperfect defense is better than not even trying.

There won't ever be a consensus of experts. That whole concept is one I've really come to hate over the years. When it comes to decisions about what to do, versus the outcome of replicable experiments on nature in lab conditions, there is always disagreement and there always will be. The idea that any decision can be resolved by a bunch of scientists sitting in a committee beard stroking doesn't reflect how people really work.

Amongst other problems, the term "expert" is ill defined (see discussion above about mathematicians) and there's always value in contrarianism for people who aren't directly making decisions. If they're wrong nobody will remember and there's nearly no reputational impact. If they're right, they can win fame and glory.

Do you have sources for these claims?
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> The problem with that is, once you lift the lockdown it will simply start all over again.

Well, no, because the world at the end of the lockdown is not the same as the world before the disease started spreading. Some differences:

- People now know there is a dangerous disease and how to act and sanitize to mitigate its spread.

- Manufacturing and other logistics for medical providers have had the time of the lockdown to ramp up.

- Testing has had the time of the lockdown to ramp up.

- A vaccine is that much further along--which is the only viable long-term strategy.

- And most important, scientific understanding of the disease has had that much longer to develop.

Britain's "expose the youngsters" strategy has a terrible flaw, which is that we don't know if the disease is actually safe for young people! All we know are some basic statistics about messy data that was reported by overwhelmed medical systems with spotty testing.

There are reliable reports of a) some young people getting very sick from this disease, b) people who seem to have recovered going back into decline and in some cases death, and c) long-term lung damage among those who did not die.

The ideas that this disease is somehow safe for young people, and that contracting it once confers long-term immunity, are ideas that are yet to be scientifically proven. They are, for now, at best heuristics to aid triage.

Do you have some links with reliable reports of young people getting sick and other cases you told?
Singapore has had a handful of cases of children getting it. A six-month old caught it and took nearly three weeks to recover:

https://co.vid19.sg/cases/singapore-case-28-6-month-old-male...

A 5 year-old was in hospital for six days, but has been discharged today:

https://co.vid19.sg/cases/singapore-case-160-5-year-old-male...

A 17-year old evacuated from Wuhan tested positive, but never showed any symptoms during the 3 weeks he was quarantined despite having the virus:

https://co.vid19.sg/cases/singapore-case-23-17-year-old-male...

(There's more cases that can be explored on the Singaporean website.)

This is nothing like the parent implied.
Exactly this. I don’t have published numbers to back the following, but we expect them after the weekend. Over half of ICU admitted covid-19 patients in the Netherlands are <50 years old. I get this information from friends and colleagues working in several hospitals. If this turns out to not be a fluke, the young are much more affected by this corona virus vs normal flu.
The distribution of age of corona patients on the ICU is NOT the same as the age distribution of all corona patients vs. disease severity. It could be and quite possibly is the case that many people below the age of 50 are infected but never reach an ICU. Most get better without severe symptoms, so looking at ICU admission stats is misleading if you extrapolate the data to the whole population.

I hate that this fact is spreading in the Netherlands without a proper explanation.

It seems like trying to time the stock market. You can make an educated guess, but in the end it's still a guess.
Unless, oh I don't know, you test for the disease.
Please don't post duplicate comments to HN (https://news.ycombinator.com/item?id=22577808). It strictly lowers the signal/noise ratio and makes merging threads a nightmare.
Merging threads?
Sometimes there are two (or more) threads for what is essentially the same story. When this happens, Dan (or one of the other moderators) frequently chooses one thread to keep, and copies the comments from the thread(s) to be deleted into the thread to be kept. If commenters have already posted the same comment to both threads, this requires more manual cleanup by the moderators. There's a lot of moderation that happens behind the scenes here to keep the site as usable as it is.
Why would operating as normal and mostly ignoring the problem cause a "slower initial burn"?

It won't. This is nonsense of the most obvious kind, because we're already past the stage where the virus is spreading quickly.

In fact the reverse is likely to be true. Lockdown minimises the number with the disease, but that number is not zero.

Which means that if immunity is possible (questionable for a CV, but let's pretend), immunity will spread wider and wider in each lockdown wave - and the health system won't be swamped.

This plays for time, raising the odds that a vaccine or some other treatment will appear.

Successive lockdowns will do exactly what they're supposed to do - spread out the peaks, minimise casualties over time, and minimise health system stress. (Although it will still be very high.)

What they won't do is keep businesses afloat. Mass bankruptcies are going to be a huge problem throughout the entire global economy.

Other countries understand this, and are stepping in with financial measures to help. Presumably the UK doesn't want to do this.

The tell is the fact that the government has plans to quarantine for four months - i.e. place under house arrest - over-70s who are infected. Without access to intensive care - it won't be available if the NHS is swamped - the mortality rate in this demographic is going to be higher than that of any other developed country. It could easily be twice the nominal 15% CFR for this demo in China.

It's hard to avoid the conclusion that the real plan is to cull the old and sick while pretending that's not happening.

(comment deleted)
They're not operating as normal: they're telling anyone with a cough to self-isolate for seven days. And the plan isn't to quarantine over 70s who are infected: it's to quarantine them all, when they're not infected.
I believe the current UK Gov’s huge majority and long remaining term allow them to make decisions that many other countries would not be able to make at this time. I think they’re right, not that this makes things any easier, both my parents are in their mid 70’s and have health problems.
As far as I know, they did not communicate an overall strategy or comprehensive action plan. The basis of this thread are a series of tweets making assumptions about what the government strategy could be (given a lack of measures taken as a basis).

I do not understand how not communicating a comprehensive action plan is meant to be the harder choice ("a decision many other countries [...] not able to make") when contrasted with messures such as declaring national emergencies and widespread lockdowns of public life.

They held a press conference live streamed on YouTube where the PM and the two chief scientific advisors answered questions and explained their strategy for nearly an hour. The answer to one question alone took over ten minutes. You may not be aware of their communication about their strategy but it's on YouTube waiting for you.
That hour long press conference, that I’ve seen live, can be condensed in don’t do anything at all, let’s get 60% of the population infected so we’ll have herd immunity.
The lockdown as implemented by Italy and France aims at slowing down the spreading of the virus. It is not meant as a strategy to overcome the virus. It is meant to flatten the curve of the exponential growth of infection to minimize overloading the health system and to provide more time for preparation and for the acquisition of best practices regarding the situation. There is no disillusion that this might somehow stop the virus. The expected total infected percentage of population, with lockdowns is still in the range of 50-60%. Italy went into lockdown on March 9th when # of new cases reached 1791 and total deaths was 463. This does not seem to qualify as a very drastic early lockdown, as stated by parent.

Given everything we know regarding exponential spread, the high percentage of cases requiring icu treatment, and the mortality rate, I fail to see how the absence of any measures to mitigate the spreading of the virus makes sense.

The assumption that there are only two viable strategies, lockdown & no measures, is a plain wrong oversimplification. There is a wide range of intermediary steps that can be taken in between to attempt to slow down the virus.

Attempting to minimize the degree of overload on the health system by applying such measures in a coordinated fashion is meant to reduce casualties caused by system overload.

Those are good points. Because Italy was hit hardest first they had very little time to prepare. The UK has had about an extra month, which puts us in a different strategic position, so we might be able to afford an approach not viable for Italy.
How does the UK have an extra month, exactly ?

It did not take Italy 1 month to to go from 1,143 (today's UK number) positives to 21,157 (today's Italy number, per https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.h...), did it ?

Testing in Italy was far less, the totals for there need to be inferred from the deaths and cases and the amount of testing!
Italy had 21 deaths on the 28th feb, so 2 weeks ago.
But the response will be less pronounced here with knowledge, self isolation and a lack of kissing when greeting. A month is probably a better guess than 2 weeks, but not a single person knows is rather the point...
It takes a long time to acquire respirators and to train anesthesiologists.
One region of Italy is close to their ICU beds limit, despite a full lockdown. And they have more beds per person than the UK. Without a full lockdown, won't they run out of beds very quickly, thus increasing the death rate a lot?
Yes the model they operate on is around 40% of the population will get this. Even with a lower real death rate of say 1% that still leaves over 250k people dead.
Italy is almost a month ahead of most of the world in infections though, their first outbreaks were weeks ago and the source for infecting most of the rest of Europe.

A lot of the UK infections can be traced to Italian holidays, for example.

Even if the government does plan to lock down the UK eventually, every day must cost 10s of millions, you can understand the strategy to wait longer, and even to play it down a bit.

According to the growth rates along the exponential curve, it seems more like a week or two than a month.
The average age of a fatal case is still north on 80 years.

The UK plan is effectively to get as many people as possible that are young, and thus at a super low risk of needing hospitalization to get infected, so that they can recover and then be immune, thus making it hard for the virus to sweep through again. If 30% or more of the population were immune, it would be much harder to get a new outbreak started. With a lockdown, either the lockdown suppresses spread, in which case ending the lockdown risks re-igniting the epidemic, or it doesn't, in which case it didn't help materially anyway.

If the UK can get 10x or more of the cases with only the same hospitalization numbers, they'll be in better shape than everywhere else.

The core question ends up being whether they're able to effectively inoculate that many young people without it spreading to just everybody.

Flattening the curve preserves medical capacity somewhat, but it also prolongs the epidemic. And since the lockdowns required to do the flattening have their own cost on lives, it's unclear whether the incremental increase in the number of lives that the medical system can preserve will or will not exceed the number of other lives caught short because the disease and also the lockdowns are extended by the extra time.

You might not be saving lives, just changing which people die.

Or you might save some, or you might lose more. Counting in advance is... let's say nontrivial. Even counting afterward will be hard and full of wide error bars.

It's relatively easy to count how many died directly from an illness, difficult to count how many will die because they delayed necessary non-emergency care for 4 months (unrelated to the virus except for the need to preserve hospital capacity or avoid infection risk) instead of 2 months because the outbreak was prolonged, and virtually impossible to count how many die from things like "I lost my job and my life savings at the same time, and I never fully recovered, and now my whole family is much poorer, which gives us higher all-cause mortality"

Everybody's talking about the first group. Occasionally, I see people admit that the second might exist and be non-empty. But, I keep feeling like I'm the only person on HN (and in my regular life) reminding people that the economy actually affects real life in major ways. (I'm probably not the only one, but still...)

Are we sure that you're immune once you've been infected?
Certain? No. Nobody can realistically be certain yet.

There is only one case that I've been able to find of a person who was diagnosed twice that can't easily be explained away as having been discharged while still infected. And even that case might be one like that.

We only know that you are likely to be immune for six month. Whether you will have life time immunity is anyone’s guess.
No. There might be even opposite effect - antibodies might make subsequent reinfections easier. That happened with some previous coronavirus. As well as with some vaccinations that didn't generate sufficient amount of antibodies - some kids acquired some illness much faster than non-vaccinated ones because the vaccine wasn't strong enough.

Current coronavirus has already multiple distinct strains. Even if they don't mutate further, we would need multiple vaccines. They might also mutate to something more deadly, given the COVID-19 is a mutation of the original SARS with some characteristics of HIV and Ebola.

We are in uncharted territory.

> [...] antibodies might make subsequent reinfections easier. That happened with some previous coronavirus.

I never read about this, can you point me to a source, please?

What exactly is the risk of needing hospitalisation if you are young? Does anybody know?
It's too early to say with reliable data. We will definitely know in 2-3 weeks with data from many European countries. In Italy, it looks like the percentage of younger hospitalised people is 12%, but growing.

https://www.independent.co.uk/news/world/europe/coronavirus-...

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That is not 12% of cases. That is 12% of hospitalizations are under the age for 50.

The overall hospitalization rate is difficult to know, due to the huge inaccuracies in the case numbers.

(comment deleted)
12% of _COVID ICU patients_ in Italy are below 50 years old. Note that this doesn't let us answer the question of how common are ICU cases among young infected people.
And the question was about hospital admissions not ICU admissions anyway.
> The UK plan is effectively to get as many people as possible that are young, and thus at a super low risk of needing hospitalization to get infected

The risk is already not that low at 55-65. These are people that are working and thus very likely to catch it.

51% of patients requiring intensive care in Italy are in the 50-70 range. 12% are younger than 50.
The first ICU patient in Italy was a 38-year old man who ran two half marathons a week before hospitalization. Iranian 22-year old futsal national team member passed away as well. Many young people have damaged lugs for life after surviving on ICU. I am not sure why people downplay the potential of damage for younger and healthier people just because it predominantly targets old and sick people. The virus might also mutate to more deadly strains.
How do you target young people exclusively? You can't.

The only thing that has worked is China/South Korea style careful tracking, rapid and extensive testing and strict quarantine measures. Nothing else so far is working.

A lot of young people still need icu treatments here in italy. If you don't flatten the curve early a lot of younglings too are gonna die and fast considering the very limited number of icu beds and the very high number of early contagions the uk seems to want to reach.
Some will. Possibly more than would have if we spread the illness over time.

But that set of outcomes has risks and costs too.

But regardless, it isn't really clear that the curve-flattening efforts are even effective. Italy is clearly experiencing an utterly uncontrolled outbreak. Despite pretty much the maximum amount of lockdown possible to achieve.

Don't believe that they have only 20k cases, or only 3k new ones today -- even with their increase in testing, they are still strongly test limited; that's why the Italian mortality rate looks so absurdly high -- they still aren't detecting most of the mild cases. (Either that or somehow the Italian version of the virus is about 10x as deadly as the everywhere-else version)

It seems much more likely that the mortality rate everywhere is relatively similar and it is the detection rate that varies. (Notice how all of the places that have really thorough testing all have the lowest -- and similar -- mortality rates? And the places with really high mortality rates are those with known inadequate testing)

To clarify current national-level lockdown effects are expected to be seen starting twelve days from now.

Some or the old red zones which covered the starting point of the infection are currently with 0 new detected cases since 3 days so it seems lockdown works IF u put them in place soon enough. [ https://translate.googleusercontent.com/translate_c?depth=1&... ]

Of course, if you ever let up on the lockdown, the disease will immediately start spreading again.
Exactly, but the government hope is to manage new cases with heavy tracking and testing as south korea is doing, so to keep the future spread far more under control. That's not possible until the current situation is resolved
The kill rate from economic loss far exceeds the virus atm.

You mightn't see it yet as people stick together but a lot of small business owners will be killing themselves in a year's time. (But most of economic deaths are more subtle)

The UK is also reducing this.

They are also coming into Summer, it's crazy to not maximize during this time.

The right thing to do would be to purposely infect people with a spray and isolate.

Society won't allow this. So we have to do other methods. They have a lot of lag and are random and exponential so probably out of real control.

With the UKs plan they can't keep it to young people. That certainly won't work.

But they will save many invisible economic lives.

To be honest, I don’t think this kind of conversation is worthwhile on HN. There are very few facts here, just opinions.

I’m all for posting authoritative information, and interesting side-effects.

But just shooting around opinions is best left for Twitter, Facebook, Reddit.

The dividing line for what's on topic on HN not fact vs. opinion, it's intellectual curiosity (https://news.ycombinator.com/newsguidelines.html). That doesn't limit itself to authoritative information, by definition.

Speculation is inevitable. The question is whether it's curious (thoughtful and fresh) or uncurious (reflexive and predictable).

But ignorant speculation during a crisis can have serious consequences. Look the fools in this thread claiming that the UK government is deliberately culling the sick and elderly. The last thing we need is ideas like that getting widespread acceptance and causing civil unrest and distrust of the authorities who are essential to managing the situation.
It's true. But ignorant speculation forms a chunk of every thread. The solution isn't to try to restrict posting to authorized opinion—that would cause more harm than good and is impossible anyway. The solution—well, there's no solution, but the best we can do—is to let the community respond when it's able to function, and moderate the threads to the extent that it's not.

When I last looked in on this one, it seemed to me that the community was functioning ok—noticeably better, in fact, than in most of the coronavirus discussions, which are highly repetitive. Repetition is bad on HN, not only because it's lacking in intellectual curiosity, but because it leads to flamewars. The mind seems to resort to conflict to amuse itself when nothing new and interesting is available.

You can read some of the rationale behind the plan here:

https://assets.publishing.service.gov.uk/government/uploads/...

I'll be honest, I watched the announcement on Friday in open mouthed horror. I can't claim I have a concrete refutation for either the broad logic or the specific evidence underlying it, but even the best case scenario is a disaster of historic proportions. I wish us luck. I wish the rest of the world luck if it turns out we're right and they're wrong.

You could think of this as the advantage of a decentralized world with every country making decisions and experimenting independently. Maybe the UK's approach is the right one, maybe it isn't. If it turns out to be more effective we'll learn something useful for future pandemics. If not then only the UK goes down the drain and we'll still learn something from it. Best of luck.
Well surely the advantage here would be for us to be able to observe and exploit the hard won knowledge of countries out ahead of us, but that doesn't appear to be what we're doing.
The thing is, what the UK is doing is truely experimental compared to what China, SK, and Italy have already done. And we won't know for sure what the full effects are until the end of the current pandemic. If the UK copied the lockdown and trace playbook already implemented, once this pandemic is over we'll have no data point for the quarantine old people only strategy to plan for the next pandemic with. How can you observe whether the UK strategy will work when nobody's done it before?
Just a note that this document is from 2011. I know you did not claim otherwise, but I had assumed from your comment it was a document prepared in response to the current situation.
Indeed, although I’m not sure what the utility of a preparedness plan prepared only after an outbreak has started would be, especially one created at the speed of the Civil Service. You can read more context (including the ethical framework and the individual studies used as evidence to underlie the plan) here:

https://www.gov.uk/guidance/pandemic-flu

The other countries are going for herd immunity too. The goal of all lock-downs and red zones is just to prevent the health system from collapsing.
Merkel apparently is trying to (or tried to), but was more coy about it. But none of the technocratic Asian governments seem to.
Because herd immunity assumes a way more behaviour and process control then you would have- even in a borg like society.

Its gerontocide, nothing more, nothing less - by incompetent/corrupt governments which will be swept away by this anyway. I greatly fear for my parents, elderly coworkers and those professors at my university.

A whole generation has grown up, incapable of proper reacting to catastrophes. What we see here, is basically appeasement to a biologic disaster, in hope of saving a ailing economy.

I think it would be rational if we knew more about the virus, but we really don't know much, given how new it is. There could be long-term health effects from contracting it, but we just don't know. The UK seems to be making a lot of assumptions, which may not bear out. +1 insane.
This is the part people are missing. We don’t know enough about the virus, and due to the extreme nature of the worst case scenarios it’s probably a better bet to act as if the worst case scenarios are true.

We can recover from an economic hit. We’ve done it several times before, and there are several tools that can be used. A major pandemic with mutating viruses is not something we are as prepared for.

Here is a link to the Coronavirus Action Plan on GOV.UK: https://www.gov.uk/government/publications/coronavirus-actio...

I would suggest anyone read this and other official publications before any Twitter thread to understand the UK government's approach to the virus. Large, complex decisions are hopefully not made off of a few hundred word summary of the situation.

That document says "Published 3 March 2020" - do you know if it still reflects current government thinking?
I like tomp's comment from a few days ago, feels like the UK playing a game theory https://news.ycombinator.com/item?id=22555643

1) no pandemic, no action -> government was "right", avoided wasting money -> reelected

2) no pandemic, action -> government was "wrong", wasted a lot of money, damaged the economy, inconvenienced the lives of the population -> voted out

3) pandemic, no action -> government was "wrong", caused loss of lives and damaged the economy -> voted out

4) pandemic, action - this is the trickiest scenario, so let's consider two options:

4a) pandemic, action, it works -> government was "right", saved lives, spared the economy -> reelected

4b) pandemic, action, doesn't work -> government was "wrong", their actions failed, they're incompetent -> voted out

This clip of the political sitcom Yes Minister from the 1980s is making the rounds on our social media, as it explains that thought process succinctly, and hilariously:

https://m.youtube.com/watch?v=qNjFIwRYEIo

A better analogy might be that of Kodos the Executioner from an episode of the original Star Trek series: https://en.wikipedia.org/wiki/The_Conscience_of_the_King. Guess right and be hailed as saving as many lives as one practically could in the face of disaster; guess wrong and be remembered as a mass murderer. Never thought I'd see it happen in real life.

(For Simpsons fans, this character is the one from which Kodos of Kodos & Kang originates.)

What's the title of the show? :D
(comment deleted)
'Yes Minister'. There is also a follow up series called 'Yes Prime Minister'. Very funny stuff - especially if you have any insight into the public service bureaucracy.
If you haven't heard of them, The Thick of It is basically a modern version of this show. By Armando Ianucci, the man who went on to make Veep (with Julia Louis Dreyfuss). Both series have been praised by insiders who say "The show is just like what happens in reality!".

He's also made the movies "In The Loop", set in the run up to the Iraq War, and "The Death of Stalin".

There is already a pandemic, so it isn't a question of pandemic or no pandemic. It's a question of if the medical system gets overwhelmed. It's also hard to judge because spending lots of money and enlisting extreme measures may slow the virus so much it looks as if it wasn't that dangerous to begin with. In which case both sides would be using it as a talking point.
Since there's already a pandemic, I'll assume when you're saying "pandemic" you mean more specifically "epidemic in the UK". Even then, there's some fallacy in your list.

In the best case -- if action is taken and it contains the spread -- then there is no epidemic and it looks like overreaction. Even if it slows the spread allowing the health care system to keep up and keeps the fatality rate fairly low you'll get people claiming it wasn't as big a deal and that whatever action was taken was an overreaction.

This happened with Y2K [1], it happens with hurricane warnings when the storms fizzle out, and despite the glaring evidence of what happens with inaction (China, Italy) there should be little doubt people will be talking about 'overreactions' in any countries that do take action that turns out to be effective.

It's the same problem that nobody goes to a show and says "Wow, the sound technician did a great job, because nobody backstage had a hot mic while they were in the bathroom!"

[1] https://news.ycombinator.com/item?id=22556156

I don't think anyone will accuse any government of overreaction, given the state we're in - there's many countries, acting independently, with different outcomes / progressions of the pandemic ... it will be very easy to look back in a year or so (hopefully) and say precisely which governments did well and which did not, possibly even precisely which actions led to the outcomes
Nah, that was the thinking before the pandemic, when "action" was either close the borders and crash the economy, or not and hope that nothing happens.

Now, I think the following consequences need to be taken into account:

(1) politicians have very little skin in the game (given they have priority access to hospitals, security, flights, ...)

(2) the only skin in the game is next election, which in the UK won't happen for another 5 years, so literally who cares (a.k.a. this won't affect Johnson's decision-making)

(3) capacity - NHS in the case of the UK - of which we (the public) have very little information, and the government (Johnson) has a lot - he might think that if there's even less capacity than in Italy, it makes no sense to even try their strategy

(4) what other countries do - a disaster isn't really a disaster if it's no worse than other countries... and Italy is pretty bad already, so it makes some sense to do something else (can hardly be worse than Italy)... this is also why I think Trump won't fare that bad, as long as the US outcome is better than EU (which is might still be, it's a bigger country with literally more space for people to self-isolate, and banned flights with China a while ago - not sure if that'll have an effect at all but it might) he should be fine

(hope not a problem that I brought up your comment but I liked it much)
This doesn't make sense as the next general election here is in 2024 and however coronavirus is handled will be in the distance by then. Consider that the Labour government started a very unpopular war in 2003 and then won a landslide two years later in 2005 - and they were in the middle of fighting it.
Scientifically, yes. Politically, suicide.

Herd immunity is what you hope for once the infection has gone through the population. To the extent that they try to build it by telling people they must be infected with it (questionable, and arguably a misinterpretation of public statements) it will be perceived as an attempt to cull the lower classes for the benefit of the ruling ones.

Except it seems to predominantly affect the elderly, who skew richer and more conservative.
Scientifically, yes? First do we have conclusion that people are immune to coronavirus once infected? Isn't the disease too new to know that? Secondly have we done any experiments and have any evidence that this will work in a smaller scale? Any scale? I thought science is about evidence and repeatability. If anything this will be a large scale human experiment at best without any informed consent given.
Please read the whole comment instead of just the first couple of words.
People are gonna get infected. At least 70% of population as everyone already says.. however. to slow the total run on health services, most of the countries adopt some sort of attempt at mitigating the aforementioned health services onslaught. This does not do that. This is literally.. a giant shoulder shrug to the Populace.
I strongly disagree with the approach in the UK. We should be following the WHO guidelines and the rest of Europe

It feels like we're the big version of one of those corona-virus cruise ships