> ...Here we investigate the geographic clustering of common genetic variants that influence complex traits in a sample of ~450,000 individuals from Great Britain.... The level of geographic clustering is correlated with genetic associations between complex traits and regional measures of SES, health and cultural outcomes. Our results are consistent with the hypothesis that social stratification leaves visible marks in geographic arrangements of common allele frequencies and gene–environment correlations.
This study analyzed genetic data from ~450,000 British individuals and found that genetic variants associated with traits like educational attainment, personality, and health are geographically clustered across Great Britain, with the strongest clustering seen for education-related genes. The researchers discovered that people with genetic predispositions for higher educational attainment tend to migrate away from economically disadvantaged areas (like former coal mining regions), while those with lower genetic predispositions are more likely to remain in or move to these areas. This migration pattern based on socioeconomic factors has created visible geographic clustering of trait-associated genes that correlates with regional differences in education, health, income, and even political voting patterns - essentially showing how social stratification leaves genetic "footprints" on the geographic landscape.
It would be interesting to compare this to former communist countries. Personally I live in a modernized “commie block” style building in one such country (as a foreigner) and I very much appreciate the fact that residents come from a wide variety of social classes. There is certainly still a class system here, but it definitely is orders of magnitude less embedded than in Britain.
Migration and reassortment events in the US would include depopulation of Appalachian coal fields, the migration of farm kids from rural counties as farm size increased, and core city to suburban movement in rust belt cities as manufacturing decreased.
Most of my high school mates from a rural county who went to college never returned to a rural area. Those who stayed behind were disproportionately from the lower half of the class.
"The book follows relatively successful and unsuccessful extended families through the centuries in England, the United States, Sweden, India, China, Taiwan, Japan, Korea, and Chile. Clark uses an innovative technique of following families by seeing whether or not rare surnames kept turning up in university enrollment records, registers of physicians, lists of members of parliament, and other similar contemporary historical registers. Clark finds that the persistence of high or low social status is greater than would be expected from the generally accepted correlations of income between parents and children, conflicting with virtually all measures of social mobility previously developed by other researchers, which Clark claims are flawed. According to Clark, social mobility proceeds at a similar rate in all of the societies and in all the periods of history studied – with the exceptions of social groups with higher endogamy (tendency to marry within the same group), who experience higher social persistence and therefore even lower social mobility.[1][2]"
Having quickly scanned the paper.... it does not appear to have studied social class, but educational attainment and geographic mobility. Further, for the genetic correlation with educational attainment r^2=0.06 (Fig. 2) which is perhaps not exactly a high correlation?
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[ 3.3 ms ] story [ 32.7 ms ] thread> ...Here we investigate the geographic clustering of common genetic variants that influence complex traits in a sample of ~450,000 individuals from Great Britain.... The level of geographic clustering is correlated with genetic associations between complex traits and regional measures of SES, health and cultural outcomes. Our results are consistent with the hypothesis that social stratification leaves visible marks in geographic arrangements of common allele frequencies and gene–environment correlations.
This study analyzed genetic data from ~450,000 British individuals and found that genetic variants associated with traits like educational attainment, personality, and health are geographically clustered across Great Britain, with the strongest clustering seen for education-related genes. The researchers discovered that people with genetic predispositions for higher educational attainment tend to migrate away from economically disadvantaged areas (like former coal mining regions), while those with lower genetic predispositions are more likely to remain in or move to these areas. This migration pattern based on socioeconomic factors has created visible geographic clustering of trait-associated genes that correlates with regional differences in education, health, income, and even political voting patterns - essentially showing how social stratification leaves genetic "footprints" on the geographic landscape.
Before DNA analysis, anthropologists used language patterns as a signal of genetic relatedness.
Most of my high school mates from a rural county who went to college never returned to a rural area. Those who stayed behind were disproportionately from the lower half of the class.
https://en.wikipedia.org/wiki/The_Son_Also_Rises_(book)
"The book follows relatively successful and unsuccessful extended families through the centuries in England, the United States, Sweden, India, China, Taiwan, Japan, Korea, and Chile. Clark uses an innovative technique of following families by seeing whether or not rare surnames kept turning up in university enrollment records, registers of physicians, lists of members of parliament, and other similar contemporary historical registers. Clark finds that the persistence of high or low social status is greater than would be expected from the generally accepted correlations of income between parents and children, conflicting with virtually all measures of social mobility previously developed by other researchers, which Clark claims are flawed. According to Clark, social mobility proceeds at a similar rate in all of the societies and in all the periods of history studied – with the exceptions of social groups with higher endogamy (tendency to marry within the same group), who experience higher social persistence and therefore even lower social mobility.[1][2]"