Scientists reverse brain aging, with a nasal spray (stories.tamu.edu)

That PR piece was brutal to navigate. Undoubtedly punched up by AI, it took far too long to even understand what the treatment entailed.

The link to the actual paper was appreciated. The context of whether findings will generalize outside of mouse models can depend a lot on specifics of the problem.

Then they get murdered...

That's a surprisingly underused plot for a sci Fi horror film.

Considering the grand total of experiments we've ran on the little guys, I'm kinda surprised we haven't bred Mousezilla yet

You joke, but rodents make great pets, because they are very social and have a range of personalities, but most only live a few years. I knew someone with a pet retired lab rat, and it lived much longer than the average fancy rat, but even then, it didn't even live half as long as the average cat or dog.

If we could breed or treat rodents to live longer, we could keep low-resource pets without as much loss.

Damn, that’s one hell of a way to say “is this any good though?”. Too many words for such a simple question.

This short story was scarier to me as a kid than anything else I read at the time.

The article is also heavily ai generated, I call bs on every single bit

Tell that to Bryan Johnson.

This is the current big grift in anti-aging science:

1 - Find a marker correlated with aging across a large sample

2 - Find a medication or supplement that also alters that marker

3 - Do some before and after measurements of the marker with the supplement or medication, and claim that you have reversed aging. Rely on the fact that enough readers won’t look closely enough to wonder if the marker is a true independent variable that represents aging.

There is a pop theory that aging is just scurvy in slow motion and Vitamin C hypersupplementation actually goes a long way in staving it off.

Asking this honestly...if certain kinds of inflammation tend to accelerate aging, and those inflammations can be controlled or decreased, does that, in effect, at least slow (if not actually reverse) aging? Granted that the headline is sensationalized, it seems like there may still be a point being made that is valid.

I knew cocaine had to have an upside.

And OCD symptoms, and many also benefit from better impulse control. Its more effective than SSRIs for some.

NAC is one of the only known treatments for trichotillomania, a under discussed but common condition that causes people to uncontrollably pull their hair out.

NAC has also been studied to reduce nicotine and alchohol cravings as well.

What is your dosage?

The failure scenarios are fun to imagine, like uncontrollable brain growth or waking nightmares as weird side effect of centuries-old brain.