I am getting the exact opposite experience. But it is probably because I am in a domain where code/software is a tool, not the product. I find myself learning exponentially faster and more. For example, I am working…
I don't disagree with Bambu from an operational standpoint, but disagree with their handling of this. They are offering a cloud infrastructure that allows users to remote control the printer via their software. If they…
I have a data science/engineering background. From my perspective, using AI is like mining the solution space for optimality. The solution space is the combinatorics of the billions of parameters and their…
I AI coded an entire platform for my work. It works great for me. I also recognize that this is not something I want to make into a commercial product because it was so easy that there's just no value. I think this…
Yeah this is the simpler and also effective strategy. A lot of people are building sophisticated AST RAG models. But you really just need to ask Claude to generally build a semantic index for each large-ish piece of…
Just write a Claude OS already.
I did this in the beginning and realized I never went back to it. I think we have to learn to embrace the chaos. We can try to place a couple of anchors in the search space by having Claude summarize the code base every…
Were there any discussion from either company about giving government access to consumer data from the the consumer product?
It's a different skillset and way of thinking. Engineers tend to think vertically deep on technical problems. With AI, you have to think horizontally broad and vertically up on the architectural problem. The trick is to…
Pretty cool technique using complementary overhangs and toehold sequences to generate a 3-way heteroduplex, ligate knick, and then remove barcode duplex. They don't give much details on how the barcode duplex is removed…
I am unsure of the impact of this to the regular consumer as this seems like a pretty niche area. But it's kinda shitty that interpersonal relationships of two companies are impacting their customers negatively. The…
It reeks a bit of tech self importance. From an overall business context, you balance time/effort vs short/long term reward and design or fix things when you need to. There are many dials to manipulate in a business to…
So the queen can lay 3 types: hybrid female, Ibiricus male, structor male. Did they do karyotyping? Is it actually that the queen somehow removed its own genetic material from the nuclei or does it somehow get silenced…
The haplotype phasing strategy is the key method here. The phasing method is described in a previous paper: https://www.nature.com/articles/s10038-022-01049-6
I think this sentiment has probably been echoed through the ages. It feels like there's an assumption that we've reached some kind of a complexity ceiling and compressing complexity below us will just make us dumb? What…
It might not be the mainstream on HN, but most popular polls I've seen show similar trends of a lesser proportion of people wanting to live longer, citing the same societal collapse concerns. In any case, whether…
This isn't an unpopular opinion. I would argue this is the mainstream argument. I think all medical advances benefit the wealthy first and then becomes more affordable over time. The term "aging" seems to trigger a lot…
At a higher level, MCP seems wants to enforce a standard where no standard exists. I get that the low level technical implementation allows AI to utilize these tools. But there doesn't seem to be any standardization or…
Learning biology is a great insight to how humans think about complex systems. We tend to utilize a reductionist and engineering approach to figure out how things work. This is a perfectly valid approach when building…
I don’t think we are going to agree on this. At the end of the day we are really just disagreeing on how seriously we should take AI-ification of software engineering. I take a lighter stance that it’s mostly harmless…
Sure. But it's not really about you. I wouldn't break into someone's house and tell them they painted their house an uninformed color. If something sucks or won't scale, it will sort itself out in the market.
[flagged]
I think this is just subject to normal market forces and very product dependent? If you have engineering skills that are not easily found, then you can ask for more. If the founders don't give it to you, then they might…
TXTL systems already works. And there are antibodies (not many) that can only be produced cell free. The problem is really scale.
Cell-free synthesis is the next step. Theres slow progress, but very interesting operational models if it works.
I am getting the exact opposite experience. But it is probably because I am in a domain where code/software is a tool, not the product. I find myself learning exponentially faster and more. For example, I am working…
I don't disagree with Bambu from an operational standpoint, but disagree with their handling of this. They are offering a cloud infrastructure that allows users to remote control the printer via their software. If they…
I have a data science/engineering background. From my perspective, using AI is like mining the solution space for optimality. The solution space is the combinatorics of the billions of parameters and their…
I AI coded an entire platform for my work. It works great for me. I also recognize that this is not something I want to make into a commercial product because it was so easy that there's just no value. I think this…
Yeah this is the simpler and also effective strategy. A lot of people are building sophisticated AST RAG models. But you really just need to ask Claude to generally build a semantic index for each large-ish piece of…
Just write a Claude OS already.
I did this in the beginning and realized I never went back to it. I think we have to learn to embrace the chaos. We can try to place a couple of anchors in the search space by having Claude summarize the code base every…
Were there any discussion from either company about giving government access to consumer data from the the consumer product?
It's a different skillset and way of thinking. Engineers tend to think vertically deep on technical problems. With AI, you have to think horizontally broad and vertically up on the architectural problem. The trick is to…
Pretty cool technique using complementary overhangs and toehold sequences to generate a 3-way heteroduplex, ligate knick, and then remove barcode duplex. They don't give much details on how the barcode duplex is removed…
I am unsure of the impact of this to the regular consumer as this seems like a pretty niche area. But it's kinda shitty that interpersonal relationships of two companies are impacting their customers negatively. The…
It reeks a bit of tech self importance. From an overall business context, you balance time/effort vs short/long term reward and design or fix things when you need to. There are many dials to manipulate in a business to…
So the queen can lay 3 types: hybrid female, Ibiricus male, structor male. Did they do karyotyping? Is it actually that the queen somehow removed its own genetic material from the nuclei or does it somehow get silenced…
The haplotype phasing strategy is the key method here. The phasing method is described in a previous paper: https://www.nature.com/articles/s10038-022-01049-6
I think this sentiment has probably been echoed through the ages. It feels like there's an assumption that we've reached some kind of a complexity ceiling and compressing complexity below us will just make us dumb? What…
It might not be the mainstream on HN, but most popular polls I've seen show similar trends of a lesser proportion of people wanting to live longer, citing the same societal collapse concerns. In any case, whether…
This isn't an unpopular opinion. I would argue this is the mainstream argument. I think all medical advances benefit the wealthy first and then becomes more affordable over time. The term "aging" seems to trigger a lot…
At a higher level, MCP seems wants to enforce a standard where no standard exists. I get that the low level technical implementation allows AI to utilize these tools. But there doesn't seem to be any standardization or…
Learning biology is a great insight to how humans think about complex systems. We tend to utilize a reductionist and engineering approach to figure out how things work. This is a perfectly valid approach when building…
I don’t think we are going to agree on this. At the end of the day we are really just disagreeing on how seriously we should take AI-ification of software engineering. I take a lighter stance that it’s mostly harmless…
Sure. But it's not really about you. I wouldn't break into someone's house and tell them they painted their house an uninformed color. If something sucks or won't scale, it will sort itself out in the market.
[flagged]
I think this is just subject to normal market forces and very product dependent? If you have engineering skills that are not easily found, then you can ask for more. If the founders don't give it to you, then they might…
TXTL systems already works. And there are antibodies (not many) that can only be produced cell free. The problem is really scale.
Cell-free synthesis is the next step. Theres slow progress, but very interesting operational models if it works.