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I'm curious if we know of anything that can work prophylactically to alter neurochemistry and render someone resistant to psychological stress and burnout. For example, could that be done with an SSRI (even for someone…

Several large entities like Netflix, Spotify, Epic Games, and Tinder seem to be successfully avoiding the “App Store Tax” (30% on all purchases) seemingly on account of their size and clout. The Financial Times (much…

I’m having trouble finding a good vim solution for jumping to definitions and renaming that also supports pipenv. So far I’ve tried ctags (which sucks) and am now giving python language server a try but it’s proving to…

I know some people working in this capacity at VC firms. They’re sometimes domain experts. And their purpose is to sit in on relevant pitches. But their purpose there is to be benched until they arrive at a fundable…

I want to structure contracts to represent: Bitcoin to <$1000 within 5 years. Is anyone making a market to support that kind of bet?

Looking for a recommendation on resources aimed improving the invite rate on a social app. I’ve scoured the more generic and obvious sources like Hooked, Influence, and related works on behavioral psychology. Wondering…

There's been a lot of exploration on the subject of UBI lately and there seems to be steadily increasing agreement that it's the only viable approach in the long run. But there are something like 3B+ people in the world…

It seems (in the US) landing in the upper middle class means that you might face an unusually bad crunch in finances and lifestyle, despite making a salary at or above 95th %: (1) There's a gray zone in financial aid,…

Could be a book, YouTube channel, TV show, movie, video game, blog, etc.

Context: have seen PCP, multiple specialists, taken a lot of blood tests, and have done considerable research, without receiving a concrete diagnosis (in the US). Chances are I'm experiencing some undetectable…

I'm scoping out solutions and debating between using Twilio/Plivo or an open source solution like https://github.com/coturn/coturn. Does anyone have experience with the cost dynamics of one vs the other? I imagine it…

I’ve recently become very interested in lasting behavioral modification after enduring too many failed efforts and regressions over time. Looking for any good resources on the subject as well as personal anecdata.

I'm really interested in improving dev agility by making better choices up and down the stack. I want to get better/faster at shipping MVPs and early stage products. Currently use things like: React, React Native, Flow,…

I was just hooking my account up to Abacus and the connection option for Chase takes you to a form at plaid.com to input Chase login credentials. How is this even remotely acceptable?

I’m curious if anyone has ever dealt with a medical issue that doctors couldn’t adequately diagnose and then proceeded to conduct independent research. It seems to me like the medical system is grossly inefficient if…

Does anyone know of a good checklist of healthy habits (e.g. stand more, floss, multivitamin daily, SPF moisturizer, meditate, etc). I'm looking for something as comprehensive as possible. Thanks!

Many people never try to build a company or never come across a problem they think is worth solving. But I'm curious about those who have (or have considered it) and then, for whatever reason, opted out of the path.…

I'm finding it difficult to locate good Node project examples on Github (particularly using ES6). It's hard in general to get a sense of best practices around architecting a Node app and writing 'proper' Node code, so…

I'm noticing that it seems to be a serious competitive disadvantage to have children if you're in tech. You get more locked in to your path, can't take as many risks, and may have a lot less free time to experiment and…