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Old Vice documentary about it. This is where I had first heard about it. Used to be really hard to find the honey online, like only one or 2 places that sold it

https://youtu.be/wDOvmhqvIA8

Thank you! I couldn't make myself read this entire LLM-generated article.
What makes you say it's LLM?

> Every article you read here is written by university scholars and researchers with deep expertise in their subjects, sharing their knowledge in their own words. We don’t oversimplify complicated issues, but we do explain and clarify. We believe bringing the voices of experts into the public discourse is good for democracy.

Such assurances mean almost nothing these days. But to be frank this specific article doesn't seem particularly AI to me.
Dunno about AI, but I was turned away by the sheer amount of ad spam on the site
> What makes you say it's LLM?

Probably the usual "big words hard" mindset of people who aren't used to reading well-written prose.

Quite the opposite. It's the completely devoid of creativity section titles, the use of triades, and the general rhythm of the text. All of this garnered with the general sense of filler content...
I imagine the native also built up tolerance over generations, not just knowledge as the article contends . Dying from a specific action is quite the evolutionary motivator
> Dying from a specific action is quite the evolutionary motivator

Only if it is before you breed, or you kill your own kids.

A lot of things sold online can stop your heart.
They mention the toxin comes from the rhododendron flower. I remember camping in North Carolina once and one of the people I was with warned against burning anything from the rhododendron in the area, as supposedly the smoke would give you the runs.

I mostly thought they were joking, and I have no idea what specific type of rhododendron would be there (if any), but maybe there’s a glimmer of merit to it? Or maybe they were thinking of a different plant?

This was somewhere in the Blue Ridge Mountains, if I remember correctly.

i believe ingestion is the primary concern, but the smoke can also lead to symptoms, yes.
That makes sense. We definitely weren’t going to eat random plants, but we could have easily accidentally grabbed some for firewood or kindling.
You also don't want to burn poison ivy because the oil (urushiol) is not something you want in your lungs if you are reactive to it.
I was wondering if someone would mention this. I grew up in the Blue Ridge Mountains of NC and heard this all my life. Once had a camp councilor who would inspect every twig to make sure there was none burned.

I also burned Rhododendron wood in campfires and brush fires more times than I can count without any adverse effects that I know of.

If you buy psychoactive honey/drugs online, it is on you to find out what it is and what kind of dosage you should take.
It's on you to figure out the dosage you can take, and it should be on the producer to label the dosage they're selling.
> The problem is that the gap between a medicinal dose and a toxic dose is very small

What's this claim based on? I don't think it's the rat study linked nearby. I looked through it and they didn't really compare doses.

If it's a linear effect on dropping blood pressure, that seems like an overblown way to talk about it. If it's something else, I'd love to hear more.

I also wondered why, if it has this effect, it has not been purified to a standard concentration (or synthesized) and used to treat high blood pressure. Possibly because accidental overdose can be fatal?
Grayanotoxin is a neurotoxin with a lot of unpleasant side effects. It would make a terrible drug for high blood pressure.
There could be a case for doing it for people that will refuse anything but natural and it doesn't have other problem, assuming not synthesized, but there's a problem of funding the safety studies and standardization process if a patent is unlikely to result.
If you maintain the pairing with the statement about the concentration in the honey varying, it's somewhat harder to argue that it is overblown.

The concentration varies considerably due to bees harvesting pollen from different flowers and from some batches of honey being mixed and some not.

>Eat a teaspoonful, and you might feel pleasantly warm and slightly lightheaded. Eat more than a few tablespoons, and your heart rate can drop to life-threatening levels.

Reminds me of the Futurama episode with the space bee honey. Wonder if the writers got the inspiration from this.

You’ve got to wake up.
I have a genuine fear that someone will stop me in the street one day, grab me by the shoulders and say

> You have to wake up. Please wake up. We're all here at your bedside waiting for you to wake up. Just wake up. We love you. Please.

And I'm convinced it's because of that episode.

My genuine fear is that you’ll just brush me off with a sensible chuckle and keep sleepwalking on down the street.

But seriously, I find that the one recurring theme in nightmares I have is that people simply won’t believe me.

Wait till you're 65. It's more than disbelief, people start to actively moronify you. I'm not that age yet, but I've see it happening to purple my parent's age
Or women of any age in certain contexts, like buying a car, or explaining to a doctor that some abdominal pain is not imaginary or temporary.
I don't think that that issue is inherent to women. I think it's inherent to everyone and we get affected on different levels in different contexts.

Any man who's been told to "man up" (most) has experienced the same.

We have to find you first. The 4D labyrinth you're in is almost impossible to navigate.
Off topic, but I totally recommend you check out Total Recall (1990)

"Wake up, Mr. Quaid!"

Even further off-topic, but I recommend you and the parent poster watch the Buffy episode Normal Again, and the 116 episodes before it. Not waking up, but also an example of the "none of this is real" idea.

I'm not sure if I'm entirely joking with this recommendation. For those who haven't watched - even for a show about a vampire slayer, it gets decreasingly plausible as the series go on (as do many long running shows). I remember being hit pretty hard when this episode suddenly offered a sensible explanation for everything, but a stone-cold path to get there.

Should I feel compelled to not offer spoilers on what is probably a joke recommendation anyway (117 episodes of a decades old TV show)?

I write this message on thrift store kids doodle tablets regularly.
I can imagining that being scary two different ways. I would not want to wake up because whatever this thing is, I love it. I'm having an amazing time, dream or not.
I have a genuine fear that someone will stop me in the street one day, grab me by the shoulders and say

Kenneth! What's the frequency? What's the frequency, Kenneth!

I know of rhododendron honey from killing Pompey’s army in around 60bc.
Let me get this straight: you feel lightheaded because your heart function is compromised? Sign me up!
This is the original article and has better images IMHO.

https://theconversation.com/mad-honey-that-can-stop-your-hea...

The posted one also removes a link to the original author's Google scholar page.
And can actually be read, the other is so as-ridden that I just gave up (I know I should probably install some blocker in my phone, but I'm lazy).
But the risk is actually more broad than the article points out. Any honey where enough of the nectar comes from rhododendrons could be dangerous.

Grayanotoxin containing Rhododendron occur not just in Nepal, but in Turkey, North America, and Europe.

I think there are other plants that the bees concentrate the toxins of.

I know that West Virginia has entire Rhododendron forests. They are pretty awesome.
And yet we are only hearing of this now, whereas botulism risk for example is a widely known reason to avoid honey for infants.

It must end up being rare for some other reason.

Another is Kalmia latifolia, the mountain laurel, the state flower of Pennsylvania. According to records at the Carnegie Museum of Natural History [1], "Benjamin Smith Barton (an American botanist in the late 1700s) wrote that in the autumn and winter of the year 1790, many people died in Pennsylvania from the effects of wild honey, collected from Kalmia plants."

[1] https://carnegiemnh.org/collected-day-1959/

If anyone's interested there's also this recently released documentary in french by Hit the Road, where they show the process of collecting the honey and also the ritual side of it.

https://youtu.be/r-jZyTP4K4g

that reminds me to buy some, anyone tried it already?
Just like many of the novel synthetiser drugs, unknown substances are very dangerous. The culprit here seems to be the victim thought he was consuming regular honey.
In a linked article it said something like 77% of cases were deliberate consumption of mad honey for thereputic qualities.
I took a novel synthesizer drug in the 1980s. They called it a Moog Stabilizer.
Just use ghost pipes for your grayanotoxin.
Had to look that up and stumbled across this:

> The information about ghost pipe containing grayanotoxin is based on a single source from 1889. (Yes 1889, not 1989!)

https://unrulygardening.com/ghost-pipe-faqs/

They are also listed as endangered in several states. I see them with some regularity in Wisconsin, even had one in my yard a few years back.

This article seems rather reckless. They admit that there is insufficient evidence to secure the safety of consuming ghost pipe, and go on to talk about creating an ethanol extraction (intended for consumption), without really explaining why one would extract with ethanol. I’m all for wild medicinal remedies but in 2026 we could take a slightly more scientific approach than a paper from 1889. Funny though, it grows in my back yard, perhaps I could find I way to study the full chemical composition. I do certainly lack the equipment however.
I’m surprised it’s even legit. I’ve heard of aphrodisiac honey that’s just been laced with viagra.
Some people survive by sheer luck.
When did HN become such dweebs?

Tattletaling losers that can’t appreciate anything novel or innovative.

'Natural' is either the bees knee’s, or a death trap. Take your pick.

edit:typo

saw a video on youtube the other week, some guys made mead out of this stuff. Claimed the effects were still present. I wonder what the concentration of the psychedelic comounds ends up being vs raw honey.
You could always this stuff online.